NP_001668.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,893 Da
NCBI Official Full Name
sodium/potassium-transporting ATPase subunit beta-1
NCBI Official Synonym Full Names
ATPase Na+/K+ transporting subunit beta 1
NCBI Official Synonym Symbols
NCBI Protein Information
sodium/potassium-transporting ATPase subunit beta-1
UniProt Protein Name
Sodium/potassium-transporting ATPase subunit beta-1
UniProt Synonym Protein Names
Sodium/potassium-dependent ATPase subunit beta-1
UniProt Synonym Gene Names
NCBI Summary for ATP1B1
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
UniProt Comments for ATP1B1
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Research Articles on ATP1B1
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Products associated with anti-ATP1B1 antibody
Pathways associated with anti-ATP1B1 antibody
Diseases associated with anti-ATP1B1 antibody
Organs/Tissues associated with anti-ATP1B1 antibody
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