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anti-Atp1a1 antibody :: Rabbit anti-Human ATP1alpha1/Na+K+ ATPase1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9406602
Unit / Price
0.05 mL  /  $200 +1 FREE 8GB USB
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATP1alpha1/Na+K+ ATPase1 (Atp1a1), Polyclonal Antibody

 Also Known As   

ATP1alpha1/Na+K+ ATPase1 (Ab-23) Antibody

 Product Synonym Names    ATP1a1/Na+K+ ATPase1 (Ab-23) Antibody; A1A1; AT1A1; ATPase; Na+/K+ transporting; alpha 1 polypeptide
 Product Gene Name   

anti-Atp1a1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P06685
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody detects endogenous levels of total ATP1a1/Na+K+ ATPase1 protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1.0 mg/ml (lot specific)
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 Immunogen Type    Peptide
 Immunogen Description    Synthesized non-phosphopeptide derived from human ATP1a1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).
 Target Name    ATP1a1/Na+K+ ATPase1
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 Preparation and Storage    Store at -20 degree C
 Other Notes    Small volumes of anti-Atp1a1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-Atp1a1 antibody

   This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.Shull G.E., Biochemistry 25:8125-8132(1986).Hara Y., J. Biochem. 102:43-58(1987).Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).
 Product Categories/Family for anti-Atp1a1 antibody    Total protein Ab
 Applications Tested/Suitable for anti-Atp1a1 antibody   

Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-Atp1a1 antibody    Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
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 Immunofluorescence (IF) of anti-Atp1a1 antibody    Immunofluorescence analysis of HeLa cells, using ATP1a1/Na+K+ ATPase1 (Ab-23) antibody.
anti-Atp1a1 antibody Immunofluorescence (IF) image
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 Western Blot (WB) of anti-Atp1a1 antibody    Western blot analysis of extracts from HeLa cells, using ATP1a1/Na+K+ ATPase1 (Ab-23) antibody.
anti-Atp1a1 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-Atp1a1 antibody    Western blot analysis of extracts from K562 cells (Lane 2), using ATP1a1/Na+K+ ATPase1 (Ab-23) antiobdy. The lane on the left is treated with synthesized peptide.
anti-Atp1a1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for Atp1a1. It may not necessarily be applicable to this product.
 NCBI GI #    6978543
 NCBI GeneID    24211
 NCBI Accession #    NP_036636.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012504.1 [Other Products]
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 UniProt Primary Accession #    P06685 [Other Products]
 UniProt Secondary Accession #    Q64609 [Other Products]
 UniProt Related Accession #    P06685 [Other Products]
 Molecular Weight    113,054 Da [Similar Products]
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 NCBI Official Full Name    sodium/potassium-transporting ATPase subunit alpha-1
 NCBI Official Synonym Full Names    ATPase, Na+/K+ transporting, alpha 1 polypeptide
 NCBI Official Symbol    Atp1a1 [Similar Products]
 NCBI Official Synonym Symbols   
Nkaa1b
[Similar Products]
 NCBI Protein Information    sodium/potassium-transporting ATPase subunit alpha-1
 UniProt Protein Name    Sodium/potassium-transporting ATPase subunit alpha-1
 UniProt Synonym Protein Names   
Sodium pump subunit alpha-1
 Protein Family    Sodium/potassium-transporting ATPase
 UniProt Gene Name    Atp1a1 [Similar Products]
 UniProt Synonym Gene Names    Na(+)/K(+) ATPase alpha-1 subunit [Similar Products]
 UniProt Entry Name    AT1A1_RAT
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 NCBI Summary for Atp1a1    mediates Na+ and K+ transport; may play a role in regulation of blood pressure [RGD, Feb 2006]
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 UniProt Comments for Atp1a1    This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
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 Research Articles on Atp1a1    1. Chronic and direct silencing of basolateral Na-K-ATPase uniquely regulates brush border membrane Na absorptive pathways in intestinal epithelial cells. Specifically, SGLT1 is stimulated secondary to enhanced affinity of the cotransporter.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Atp1a1 antibodyPathways associated with anti-Atp1a1 antibody
 Reference Product  PubMed Publications
 Atp1b1 antibody  >22 publications with Atp1a1 and Atp1b1
 Atp1b3 antibody  >7 publications with Atp1a1 and Atp1b3
 Atp1b2 antibody  >5 publications with Atp1a1 and Atp1b2
 Fxyd1 antibody  >4 publications with Atp1a1 and Fxyd1
 Mapk3 antibody  >2 publications with Atp1a1 and Mapk3
 Fxyd2 antibody  >2 publications with Atp1a1 and Fxyd2
 Fxyd7 antibody  >1 publications with Atp1a1 and Fxyd7
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
Diseases associated with anti-Atp1a1 antibodyOrgans/Tissues associated with anti-Atp1a1 antibody
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >51 publications with Atp1a1 and Hypertension
 Cardiovascular Diseases Antibodies  >41 publications with Atp1a1 and Cardiovascular Diseases
 Adenoma Antibodies  >23 publications with Atp1a1 and Adenoma
 Hyperaldosteronism Antibodies  >19 publications with Atp1a1 and Hyperaldosteronism
 Kidney Diseases Antibodies  >14 publications with Atp1a1 and Kidney Diseases
 Heart Diseases Antibodies  >14 publications with Atp1a1 and Heart Diseases
 Nervous System Diseases Antibodies  >12 publications with Atp1a1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >12 publications with Atp1a1 and Disease Models, Animal
 Heart Failure Antibodies  >9 publications with Atp1a1 and Heart Failure
 Hyperplasia Antibodies  >8 publications with Atp1a1 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >51 publications with Atp1a1 and Kidney
 Adrenal Gland Antibodies  >8 publications with Atp1a1 and Adrenal Gland
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