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anti-ATP5B antibody :: Rabbit ATP5B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS855393
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATP5B, Polyclonal Antibody

★Popular Item★
 Also Known As   

ATP5B Antibody

 Product Gene Name   

anti-ATP5B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    102910
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Form/Format    Lyophilized anti-ATP5B antibody purified by peptide affinity column containing 1% BSA and 0.02% NaN3
 Concentration    100ug/200ul (lot specific)
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 Source Note    Rabbit polyclonal ATP5B (1) antibody was raised against a 16 amino acid peptide from near the intermediate of human ATP5B protein.
 Reactivity Note    Not yet tested in other species.
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-ATP5B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ATP5B antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-ATP5B antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ATP5B antibody    Peptide ELISA titer: 1:1,000-1:10,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-1:500
Optimal dilutions/concentrations should be determined by the end user.
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 Testing Data of anti-ATP5B antibody    anti-ATP5B antibody Testing Data image
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 Testing Data #2 of anti-ATP5B antibody    anti-ATP5B antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for ATP5B. It may not necessarily be applicable to this product.
 NCBI GI #    50345985
 NCBI GeneID    506
 NCBI Accession #    NP_001677.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001686 [Other Products]
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 UniProt Secondary Accession #    Q14283; A8K4X0 [Other Products]
 UniProt Related Accession #    P06576 [Other Products]
 Molecular Weight    56,560 Da
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 NCBI Official Full Name    Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (ATP5B), mRNA
 NCBI Official Synonym Full Names    ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
 NCBI Official Symbol    ATP5B [Similar Products]
 NCBI Official Synonym Symbols   
ATPMB; ATPSB; HEL-S-271
[Similar Products]
 NCBI Protein Information    ATP synthase subunit beta, mitochondrial; epididymis secretory protein Li 271; mitochondrial ATP synthase beta subunit; mitochondrial ATP synthetase, beta subunit
 UniProt Protein Name    ATP synthase subunit beta, mitochondrial
 UniProt Gene Name    ATP5B [Similar Products]
 UniProt Synonym Gene Names    ATPMB; ATPSB [Similar Products]
 UniProt Entry Name    ATPB_HUMAN
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 NCBI Summary for ATP5B    This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ATP5B    ATP5B: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Belongs to the ATPase alpha/beta chains family.

Protein type: Energy Metabolism - oxidative phosphorylation; EC 3.6.3.14; Mitochondrial; Hydrolase

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: mitochondrial proton-transporting ATP synthase, catalytic core; cell surface; membrane; mitochondrion; mitochondrial matrix; mitochondrial membrane; plasma membrane; nucleus; mitochondrial proton-transporting ATP synthase complex

Molecular Function: protein binding; MHC class I protein binding; transporter activity; ATPase activity; hydrogen ion transporting ATP synthase activity, rotational mechanism; transmembrane transporter activity; hydrogen ion transporting ATPase activity, rotational mechanism; ATP binding

Biological Process: mitochondrion organization and biogenesis; generation of precursor metabolites and energy; substrate-bound cell migration, cell release from substrate; organelle organization and biogenesis; osteoblast differentiation; cellular metabolic process; proton transport; ATP biosynthetic process; ATP hydrolysis coupled proton transport; regulation of intracellular pH; mitochondrial ATP synthesis coupled proton transport; angiogenesis; lipid metabolic process
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 Research Articles on ATP5B    1. Mitochondrial ATPsyn-beta expression and ATP synthase activity in relapsed/refractory acute myeloid leukemia patients were downregulated. This downregulated expression exhibited a positive correlation with the response to adriamycin of primary cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ATP5B antibodyPathways associated with anti-ATP5B antibody
 Reference Product  PubMed Publications
 ATP5A1 antibody  >5 publications with ATP5B and ATP5A1
 ATP5C1 antibody  >2 publications with ATP5B and ATP5C1
 ATP5L antibody  >1 publications with ATP5B and ATP5L
 ATP5H antibody  >1 publications with ATP5B and ATP5H
 ATP5O antibody  >1 publications with ATP5B and ATP5O
 ATP5D antibody  >1 publications with ATP5B and ATP5D
 ATP5F1 antibody  >1 publications with ATP5B and ATP5F1
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 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with anti-ATP5B antibodyOrgans/Tissues associated with anti-ATP5B antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >12 publications with ATP5B and Nervous System Diseases
 Disease Models, Animal Antibodies  >9 publications with ATP5B and Disease Models, Animal
 Brain Diseases Antibodies  >9 publications with ATP5B and Brain Diseases
 Atherosclerosis Antibodies  >5 publications with ATP5B and Atherosclerosis
 Lung Diseases Antibodies  >5 publications with ATP5B and Lung Diseases
 Breast Neoplasms Antibodies  >4 publications with ATP5B and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >4 publications with ATP5B and Cardiovascular Diseases
 Necrosis Antibodies  >4 publications with ATP5B and Necrosis
 Liver Diseases Antibodies  >3 publications with ATP5B and Liver Diseases
 Inflammation Antibodies  >3 publications with ATP5B and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >19 publications with ATP5B and Blood
 Muscle Antibodies  >16 publications with ATP5B and Muscle
 Brain Antibodies  >15 publications with ATP5B and Brain
 Liver Antibodies  >14 publications with ATP5B and Liver
 Vascular Antibodies  >9 publications with ATP5B and Vascular
 Lung Antibodies  >6 publications with ATP5B and Lung
 Pancreas Antibodies  >5 publications with ATP5B and Pancreas
 Kidney Antibodies  >4 publications with ATP5B and Kidney
 Mammary Gland Antibodies  >3 publications with ATP5B and Mammary Gland
 Skin Antibodies  >3 publications with ATP5B and Skin
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