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anti-ATP8A1 antibody :: Rabbit ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714745 anti-ATP8A1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 (ATP8A1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 polyclonal Antibody

 Product Synonym Names    ATPase; aminophospholipid transporter (APLT); class I; type 8A; member 1; ATP8A1; ATPASEII; ATPIA; ATPP2; MGC130042; MGC130043; MGC26327
 Product Gene Name   

anti-ATP8A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609542
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human ATP8A1
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-99109
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ATP8A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ATP8A1 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ATP8A1. It may not necessarily be applicable to this product.
 NCBI GI #    119613409
 NCBI GeneID    10396
 NCBI Accession #    EAW93003.1 [Other Products]
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 UniProt Secondary Accession #    Q32M35; Q32M36; Q4W5J7; Q4W5P2 [Other Products]
 UniProt Related Accession #    Q9Y2Q0 [Other Products]
 Molecular Weight    129,723 Da [Similar Products]
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 NCBI Official Full Name    ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1, isoform CRA_a
 NCBI Official Synonym Full Names    ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
 NCBI Official Symbol    ATP8A1 [Similar Products]
 NCBI Official Synonym Symbols   
ATPIA; ATPP2; ATPASEII
[Similar Products]
 NCBI Protein Information    phospholipid-transporting ATPase IA; ATPase II; chromaffin granule ATPase II; aminophospholipid translocase; ATPase class I type 8A member 1; probable phospholipid-transporting ATPase IA; P4-ATPase flippase complex alpha subunit ATP8A1
 UniProt Protein Name    Phospholipid-transporting ATPase IA
 UniProt Synonym Protein Names   
ATPase class I type 8A member 1; Chromaffin granule ATPase II; P4-ATPase flippase complex alpha subunit ATP8A1
 Protein Family    Phospholipid-transporting ATPase
 UniProt Gene Name    ATP8A1 [Similar Products]
 UniProt Synonym Gene Names    ATPIA [Similar Products]
 UniProt Entry Name    AT8A1_HUMAN
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 NCBI Summary for ATP8A1    The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ATP8A1    ATP8A1: May play a role in the transport of aminophospholipids from the outer to the inner leaflet of various membranes and the maintenance of asymmetric distribution of phospholipids, mainly in secretory vesicles. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Transporter, ion channel; Transporter; EC 3.6.3.1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4p13

Cellular Component: Golgi apparatus; membrane; endoplasmic reticulum; integral to membrane; plasma membrane

Molecular Function: phospholipid-translocating ATPase activity; protein binding; magnesium ion binding; ATP binding; cation-transporting ATPase activity

Biological Process: phospholipid translocation; metabolic process; learning; transmembrane transport; cation transport; positive regulation of cell migration
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 Research Articles on ATP8A1    1. the phospholipid flippase complex of ATP8A1 and CDC50A proteins has a role in cell migration
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ATP8A1 antibodyDiseases associated with anti-ATP8A1 antibody
 Products by Pathway  Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ion Transport By P-type ATPases Pathway antibodies  Ion Transport By P-type ATPases Pathway Diagram
 Peptide GPCRs Pathway antibodies  Peptide GPCRs Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with ATP8A1 and Liver Diseases
Organs/Tissues associated with anti-ATP8A1 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with ATP8A1 and Liver
 Blood Antibodies  >2 publications with ATP8A1 and Blood
 Ovary Antibodies  >1 publications with ATP8A1 and Ovary
 Lung Antibodies  >1 publications with ATP8A1 and Lung
 Spleen Antibodies  >1 publications with ATP8A1 and Spleen
 Brain Antibodies  >1 publications with ATP8A1 and Brain
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