NP_000697.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
vasopressin V1a receptor
NCBI Official Synonym Full Names
arginine vasopressin receptor 1A
NCBI Protein Information
vasopressin V1a receptor
UniProt Protein Name
Vasopressin V1a receptor
UniProt Synonym Protein Names
AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor
UniProt Synonym Gene Names
UniProt Entry Name
V1AR_HUMAN
NCBI Summary for AVPR1A
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
UniProt Comments for AVPR1A
AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q14-q15
Cellular Component: integral to plasma membrane; plasma membrane; cytoplasmic vesicle; endosome
Molecular Function: protein binding; protein kinase C binding; V1A vasopressin receptor binding; peptide hormone binding; peptide binding; vasopressin receptor activity
Biological Process: blood circulation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; cellular response to water deprivation; positive regulation of systemic arterial blood pressure; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; penile erection; positive regulation of prostaglandin biosynthetic process; response to corticosterone stimulus; grooming behavior; generation of precursor metabolites and energy; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; phospholipase C activation; positive regulation of vasoconstriction; sperm ejaculation
Product References and Citations for anti-AVPR1A antibody
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Yang, S.Y., et al. Neurosci. Lett. 479(3):197-200(2010) Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) : Yang, S.Y., et al. Psychiatry Res 178(1):199-201(2010) Binder, E.B., et al. Arch. Gen. Psychiatry 67(4):369-379(2010)
Research Articles on AVPR1A
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Products associated with anti-AVPR1A antibody
Pathways associated with anti-AVPR1A antibody
Diseases associated with anti-AVPR1A antibody
Organs/Tissues associated with anti-AVPR1A antibody
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