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anti-AZGP1 antibody :: anti-Human AZGP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9126862
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AZGP1, Polyclonal Antibody

★Popular Item★
 Also Known As   

AZGP1 Polyclonal Antibody

 Product Synonym Names    ZA2G;ZAG
 Product Gene Name   

anti-AZGP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    194460
 3D Structure    ModBase 3D Structure for P25311
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 Clonality    Polyclonal
 Isotype    IgG
 Species Reactivity    Human
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 Purity/Purification    Affinity Purification
 Concentration    1mg/ml (lot specific)
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 Source    Rabbit
 Species    Human
 Immunogen    Recombinant protein of human AZGP1
 Observed MW    40kDa
 Calculated MW    34kDa
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-AZGP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-AZGP1 antibody

   Zinc-alpha-2-glycoprotein (AZGP1) is a soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).
 Product Categories/Family for anti-AZGP1 antibody    Polyclonal
 Applications Tested/Suitable for anti-AZGP1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-AZGP1 antibody    WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
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 Western Blot (WB) of anti-AZGP1 antibody    Western blot analysis of extracts of various cell lines, using AZGP1 antibody (MBS9126862) at 1:1000 dilution. Secondary antibody: HRP Goat Anti- Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (Please Inquire). Exposure time: 90s.
anti-AZGP1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry of anti-AZGP1 antibody    Immunohistochemistry of paraffinembedded human colon using AZGP1 antibody (MBS9126862) at dilution of 1:100 (40x lens).
anti-AZGP1 antibody Immunohistochemistry (IHC) image
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 Immunohistochemistry of anti-AZGP1 antibody    Immunohistochemistry of paraffinembedded human prostate using AZGP1 antibody (MBS9126862) at dilution of 1:100 (40x lens).
anti-AZGP1 antibody Immunohistochemistry (IHC) image
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 Immunohistochemistry of anti-AZGP1 antibody    Immunohistochemistry of paraffinembedded mouse lung using AZGP1 antibody (MBS9126862) at dilution of 1:100(40x lens).
anti-AZGP1 antibody Immunohistochemistry (IHC) image
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NCBI/Uniprot data below describe general gene information for AZGP1. It may not necessarily be applicable to this product.
 NCBI GI #    292495049
 NCBI GeneID    563
 NCBI Accession #    P25311.2 [Other Products]
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 UniProt Primary Accession #    P25311 [Other Products]
 UniProt Secondary Accession #    O60386; Q5XKQ4; Q8N4N0; D6W5T8 [Other Products]
 UniProt Related Accession #    P25311 [Other Products]
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 NCBI Official Full Name    Zinc-alpha-2-glycoprotein
 NCBI Official Synonym Full Names    alpha-2-glycoprotein 1, zinc-binding
 NCBI Official Symbol    AZGP1 [Similar Products]
 NCBI Official Synonym Symbols   
ZAG; ZA2G
[Similar Products]
 NCBI Protein Information    zinc-alpha-2-glycoprotein; zn-alpha-2-GP; Zn-alpha2-glycoprotein; zn-alpha-2-glycoprotein; Alpha-2-glycoprotein, zinc
 UniProt Protein Name    Zinc-alpha-2-glycoprotein
 Protein Family    Zinc-alpha-2-glycoprotein
 UniProt Gene Name    AZGP1 [Similar Products]
 UniProt Synonym Gene Names    ZAG; ZNGP1; Zn-alpha-2-GP; Zn-alpha-2-glycoprotein [Similar Products]
 UniProt Entry Name    ZA2G_HUMAN
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 UniProt Comments for AZGP1    AZGP1: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids. Belongs to the MHC class I family.

Protein type: Cell adhesion; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: extracellular space; extracellular region; plasma membrane; nucleus; MHC class I protein complex

Molecular Function: peptide antigen binding; protein transmembrane transporter activity; glycoprotein binding; antigen binding; ribonuclease activity

Biological Process: retinal homeostasis; antigen processing and presentation; negative regulation of cell proliferation; antigen processing and presentation of peptide antigen via MHC class I; positive regulation of T cell mediated cytotoxicity; immune response; detection of chemical stimulus involved in sensory perception of bitter taste; cell adhesion
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 Research Articles on AZGP1    1. thyroid hormone up-regulates the production of zinc-alpha2-glycoprotein in the liver but not in the adipose tissue.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AZGP1 antibodyDiseases associated with anti-AZGP1 antibody
 Reference Product  PubMed Publications
 PIP antibody  >11 publications with AZGP1 and PIP
 FETUB antibody  >1 publications with AZGP1 and FETUB
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >16 publications with AZGP1 and Carcinoma
 Adenocarcinoma Antibodies  >12 publications with AZGP1 and Adenocarcinoma
 Prostatic Neoplasms Antibodies  >12 publications with AZGP1 and Prostatic Neoplasms
 Breast Neoplasms Antibodies  >9 publications with AZGP1 and Breast Neoplasms
 Kidney Diseases Antibodies  >6 publications with AZGP1 and Kidney Diseases
 Weight Loss Antibodies  >4 publications with AZGP1 and Weight Loss
 Necrosis Antibodies  >4 publications with AZGP1 and Necrosis
 Immune System Diseases Antibodies  >4 publications with AZGP1 and Immune System Diseases
 Pancreatic Neoplasms Antibodies  >3 publications with AZGP1 and Pancreatic Neoplasms
 Liver Diseases Antibodies  >3 publications with AZGP1 and Liver Diseases
Organs/Tissues associated with anti-AZGP1 antibody
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >15 publications with AZGP1 and Prostate
 Connective Tissue Antibodies  >10 publications with AZGP1 and Connective Tissue
 Kidney Antibodies  >7 publications with AZGP1 and Kidney
 Liver Antibodies  >6 publications with AZGP1 and Liver
 Lung Antibodies  >4 publications with AZGP1 and Lung
 Eye Antibodies  >4 publications with AZGP1 and Eye
 Brain Antibodies  >2 publications with AZGP1 and Brain
 Muscle Antibodies  >2 publications with AZGP1 and Muscle
 Stomach Antibodies  >1 publications with AZGP1 and Stomach
 Mouth Antibodies  >1 publications with AZGP1 and Mouth
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