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anti-ARPC3 antibody :: Rabbit anti-Human Actin-related protein 2/3 complex subunit 3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7004056
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Actin-related protein 2/3 complex subunit 3 (ARPC3), Polyclonal Antibody

 Also Known As   

Rabbit anti-human Actin-related protein 2/3 complex subunit 3 polyclonal Antibody

 Product Synonym Names    Actin-related protein 2/3 complex subunit 3 protein; Actin-related protein 2/3 complex subunit 3; Arp2/3 complex 21 kDa subunit; p21-ARC; ARPC3; ARC21;
 Product Gene Name   

anti-ARPC3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604225
 3D Structure    ModBase 3D Structure for O15145
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Actin-related protein 2/3 complex subunit 3 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68396
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ARPC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-ARPC3 antibody

   p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004).

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of This protein, the p21 subunit, has yet to be determined.
 Product Categories/Family for anti-ARPC3 antibody    Signal Transduction
 Applications Tested/Suitable for anti-ARPC3 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-ARPC3 antibody    Recommended dilution: WB:1:500-2000
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 Western Blot (WB) of anti-ARPC3 antibody    Western blot
Actin-related protein 2/3 complex subunit 3Antibody at 2ug/ml+293T whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size: 20 kDa
Observed band size: 75 kDa

anti-ARPC3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ARPC3. It may not necessarily be applicable to this product.
 NCBI GI #    514052670
 NCBI GeneID    10094
 NCBI Accession #    NP_001265485.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001278556.1 [Other Products]
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 UniProt Primary Accession #    O15145 [Other Products]
 UniProt Secondary Accession #    O00554 [Other Products]
 UniProt Related Accession #    O15145 [Other Products]
 Molecular Weight    20,547 Da
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 NCBI Official Full Name    actin-related protein 2/3 complex subunit 3 isoform 1
 NCBI Official Synonym Full Names    actin related protein 2/3 complex subunit 3
 NCBI Official Symbol    ARPC3 [Similar Products]
 NCBI Official Synonym Symbols   
ARC21; p21-Arc
[Similar Products]
 NCBI Protein Information    actin-related protein 2/3 complex subunit 3
 UniProt Protein Name    Actin-related protein 2/3 complex subunit 3
 UniProt Synonym Protein Names   
Arp2/3 complex 21 kDa subunit; p21-ARC
 Protein Family    Actin-related protein 2/3 complex
 UniProt Gene Name    ARPC3 [Similar Products]
 UniProt Synonym Gene Names    ARC21; p21-ARC [Similar Products]
 UniProt Entry Name    ARPC3_HUMAN
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 NCBI Summary for ARPC3    This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
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 UniProt Comments for ARPC3    ARPC3: one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 12q24.11

Cellular Component: actin cytoskeleton; Arp2/3 protein complex; cytosol; focal adhesion; lamellipodium; membrane

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton

Biological Process: axon guidance; cell motility; ephrin receptor signaling pathway; innate immune response; small GTPase mediated signal transduction
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 Research Articles on ARPC3    1. Endogenous Nogo-B, which may exert its effects through ARPC 2/3 and MYL-9, is necessary for the migration and contraction of airway smooth muscle cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ARPC3 antibodyPathways associated with anti-ARPC3 antibody
 Reference Product  PubMed Publications
 ARPC2 antibody  >9 publications with ARPC3 and ARPC2
 ARPC4 antibody  >6 publications with ARPC3 and ARPC4
 ARPC5 antibody  >4 publications with ARPC3 and ARPC5
 WASL antibody  >1 publications with ARPC3 and WASL
 ACTR3 antibody  >1 publications with ARPC3 and ACTR3
 ARPC1B antibody  >1 publications with ARPC3 and ARPC1B
 ACTR2 antibody  >1 publications with ARPC3 and ACTR2
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPHB-mediated Forward Signaling Pathway antibodies  EPHB-mediated Forward Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
Diseases associated with anti-ARPC3 antibodyOrgans/Tissues associated with anti-ARPC3 antibody
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >3 publications with ARPC3 and Skin Diseases
 Lung Diseases Antibodies  >1 publications with ARPC3 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with ARPC3 and Brain
 Adipose Tissue Antibodies  >2 publications with ARPC3 and Adipose Tissue
 Muscle Antibodies  >2 publications with ARPC3 and Muscle
 Skin Antibodies  >2 publications with ARPC3 and Skin
 Ovary Antibodies  >1 publications with ARPC3 and Ovary
 Blood Antibodies  >1 publications with ARPC3 and Blood
 Placenta Antibodies  >1 publications with ARPC3 and Placenta
 Intestine Antibodies  >1 publications with ARPC3 and Intestine
 Pancreas Antibodies  >1 publications with ARPC3 and Pancreas
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