NP_031523.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
29,238 Da
NCBI Official Full Name
cyclic AMP-dependent transcription factor ATF-1
NCBI Official Synonym Full Names
activating transcription factor 1
NCBI Protein Information
cyclic AMP-dependent transcription factor ATF-1
UniProt Protein Name
Cyclic AMP-dependent transcription factor ATF-1
UniProt Synonym Protein Names
Activating transcription factor 1; TCR-ATF1
UniProt Synonym Gene Names
UniProt Comments for ATF1
ATF-1: a transcription factor that is a member of the leucine zipper family. Forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. Binds the Tax-responsive element (TRE) of HTLV-I. Activated downstream of IL-1. c-Src and TRAF6 are mediators of IL-1-induced AP-1 activation. Plays an important role in the trans-activation of the MHC class II trans-activator (CIITA) promoter III in B cells.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 15|15 F1
Cellular Component: ATF1-ATF4 transcription factor complex; nucleoplasm; nucleus; transcription factor complex
Molecular Function: DNA binding; DNA binding transcription factor activity; identical protein binding; protein complex binding; protein heterodimerization activity; sequence-specific DNA binding; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Biological Process: cellular protein complex assembly; positive regulation of DNA replication; positive regulation of neuron projection development; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; transcription, DNA-dependent
Research Articles on ATF1
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Products associated with anti-ATF1 antibody
Pathways associated with anti-ATF1 antibody
Diseases associated with anti-ATF1 antibody
Organs/Tissues associated with anti-ATF1 antibody
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