Q6LD47
[Other Products]
UniProt Related Accession #
NCBI Official Full Name
adenosine A3 receptor
NCBI Official Synonym Full Names
adenosine A3 receptor
NCBI Official Synonym Symbols
A3AR; AD026; bA552M11.5; RP11-552M11.7 [Similar Products]
NCBI Protein Information
adenosine receptor A3; OTTHUMP00000013476; OTTHUMP00000013479; OTTHUMP00000013739; OTTHUMP00000082917
UniProt Protein Name
Adenosine A3 receptor protein
UniProt Entry Name
Q6LD47_HUMAN
NCBI Summary for ADORA3
This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
UniProt Comments for ADORA3
ADORA3: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p13.2
Cellular Component: mast cell granule; integral to plasma membrane; plasma membrane
Molecular Function: adenosine receptor activity, G-protein coupled
Biological Process: positive regulation of phosphoinositide 3-kinase cascade; histamine secretion by mast cell; positive regulation of leukocyte migration; adenylate cyclase activation; response to wounding; positive regulation of mast cell degranulation; positive regulation of calcium-mediated signaling; signal transduction; inflammatory response; adenosine receptor signaling pathway; regulation of heart contraction; positive regulation of inflammatory response
Research Articles on ADORA3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-ADORA3 antibody
Diseases associated with anti-ADORA3 antibody
Organs/Tissues associated with anti-ADORA3 antibody
|