NP_001268366.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,153 Da
NCBI Official Full Name
proteasomal ubiquitin receptor ADRM1 isoform 2
NCBI Official Synonym Full Names
adhesion regulating molecule 1
NCBI Protein Information
proteasomal ubiquitin receptor ADRM1
UniProt Protein Name
Proteasomal ubiquitin receptor ADRM1
UniProt Synonym Protein Names
110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Proteasome regulatory particle non-ATPase 13; hRpn13; Rpn13 homolog
UniProt Synonym Gene Names
NCBI Summary for ADRM1
This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UniProt Comments for ADRM1
ADRM1: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family.
Protein type: Cell development/differentiation; Proteasome complex
Chromosomal Location of Human Ortholog: 20q13.33
Cellular Component: cytosol; integral component of plasma membrane; membrane; nucleoplasm; plasma membrane; proteasome complex
Molecular Function: protease binding; protein binding; ubiquitin binding
Biological Process: proteasome assembly; protein deubiquitination; transcription elongation from RNA polymerase II promoter; ubiquitin-dependent protein catabolic process
Research Articles on ADRM1
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Products associated with anti-ADRM1 antibody
Diseases associated with anti-ADRM1 antibody
Organs/Tissues associated with anti-ADRM1 antibody
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