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anti-Aldh1a1 antibody :: Rabbit anti-Mouse Aldh1a1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1493348
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Aldh1a1, Polyclonal Antibody

★Popular Item★
 Also Known As   

Aldh1a1 Antibody

 Product Synonym Names    Retinal dehydrogenase 1 (EC:1.2.1.36); RALDH 1; RalDH1; Aldh1a1; Ahd-2; Ahd2; Aldh1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase; cytosolic
 Product Gene Name   

anti-Aldh1a1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P24549
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant mouse Retinal dehydrogenase 1 protein
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-Aldh1a1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Aldh1a1 antibody

   In addition to the activity on acetaldehyde and related substrates, is also involved in the oxidation of aldehydes derived from biogenic amines such as epinephrine and norepinephrine, as well as the aldehydes generated via lipid peroxidation. Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).
 Applications Tested/Suitable for anti-Aldh1a1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-Aldh1a1 antibody    Recommended dilution: WB:1:500-2000
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 Western Blot (WB) of anti-Aldh1a1 antibody    Western blot
All lanes: Aldh1a1 antibody at 8ug/ml+ Mouse eye tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa

anti-Aldh1a1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for Aldh1a1. It may not necessarily be applicable to this product.
 NCBI GI #    85861182
 NCBI GeneID    11668
 NCBI Accession #    NP_038495.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_013467.3 [Other Products]
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 UniProt Primary Accession #    P24549 [Other Products]
 UniProt Secondary Accession #    Q7TQJ0; Q811J0 [Other Products]
 UniProt Related Accession #    P24549 [Other Products]
 Molecular Weight    54,468 Da
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 NCBI Official Full Name    retinal dehydrogenase 1
 NCBI Official Synonym Full Names    aldehyde dehydrogenase family 1, subfamily A1
 NCBI Official Symbol    Aldh1a1 [Similar Products]
 NCBI Official Synonym Symbols   
E1; Ahd2; Ahd-2; Aldh1; Raldh1; Aldh1a2
[Similar Products]
 NCBI Protein Information    retinal dehydrogenase 1
 UniProt Protein Name    Retinal dehydrogenase 1
 UniProt Synonym Protein Names   
ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic
 Protein Family    Retinal dehydrogenase
 UniProt Gene Name    Aldh1a1 [Similar Products]
 UniProt Synonym Gene Names    Ahd-2; Ahd2; Aldh1; RALDH 1; RalDH1 [Similar Products]
 UniProt Entry Name    AL1A1_MOUSE
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 UniProt Comments for Aldh1a1    ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.

Protein type: Cofactor and Vitamin Metabolism - retinol; GAPs; EC 1.2.1.36; GAPs, Ras; Apoptosis; Oxidoreductase

Cellular Component: cytoplasm; nucleus

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; benzaldehyde dehydrogenase (NAD+) activity; identical protein binding; oxidoreductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; retinal dehydrogenase activity

Biological Process: 9-cis-retinoic acid biosynthetic process; 9-cis-retinoic acid metabolic process; embryonic eye morphogenesis; metabolic process; optic cup morphogenesis involved in camera-type eye development; positive regulation of apoptosis; protein homotetramerization; response to drug; response to ethanol; response to oxidative stress; retinoic acid metabolic process; retinol metabolic process
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 Research Articles on Aldh1a1    1. these experiments reveal an evolutionarily conserved GABA synthesis pathway mediated by aldehyde dehydrogenase 1a1 (ALDH1a1).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Aldh1a1 antibodyPathways associated with anti-Aldh1a1 antibody
 Reference Product  PubMed Publications
 Cyp26b1 antibody  >10 publications with Aldh1a1 and Cyp26b1
 Adh1 antibody  >10 publications with Aldh1a1 and Adh1
 Aldh1a7 antibody  >8 publications with Aldh1a1 and Aldh1a7
 Adh4 antibody  >8 publications with Aldh1a1 and Adh4
 Cyp26a1 antibody  >8 publications with Aldh1a1 and Cyp26a1
 Pitx3 antibody  >7 publications with Aldh1a1 and Pitx3
 Adh5 antibody  >4 publications with Aldh1a1 and Adh5
 Adh7 antibody  >3 publications with Aldh1a1 and Adh7
 Cyp26c1 antibody  >2 publications with Aldh1a1 and Cyp26c1
 Products by Pathway  Pathway Diagram
 Amino Acid Metabolism Pathway antibodies  Amino Acid Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Dopminergic Neurogenesis Pathway antibodies  Dopminergic Neurogenesis Pathway Diagram
 Ethanol Oxidation Pathway antibodies  Ethanol Oxidation Pathway Diagram
 Fatty Acid Omega Oxidation Pathway antibodies  Fatty Acid Omega Oxidation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Phase 1 - Functionalization Of Compounds Pathway antibodies  Phase 1 - Functionalization Of Compounds Pathway Diagram
 RA Biosynthesis Pathway antibodies  RA Biosynthesis Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
Diseases associated with anti-Aldh1a1 antibodyOrgans/Tissues associated with anti-Aldh1a1 antibody
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >33 publications with Aldh1a1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >28 publications with Aldh1a1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >25 publications with Aldh1a1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >24 publications with Aldh1a1 and Nervous System Diseases
 Brain Diseases Antibodies  >23 publications with Aldh1a1 and Brain Diseases
 Neoplasms, Experimental Antibodies  >20 publications with Aldh1a1 and Neoplasms, Experimental
 Liver Diseases Antibodies  >17 publications with Aldh1a1 and Liver Diseases
 Parkinsonian Disorders Antibodies  >14 publications with Aldh1a1 and Parkinsonian Disorders
 Liver Neoplasms Antibodies  >13 publications with Aldh1a1 and Liver Neoplasms
 Inflammation Antibodies  >11 publications with Aldh1a1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >55 publications with Aldh1a1 and Lung
 Blood Antibodies  >49 publications with Aldh1a1 and Blood
 Liver Antibodies  >48 publications with Aldh1a1 and Liver
 Brain Antibodies  >42 publications with Aldh1a1 and Brain
 Eye Antibodies  >31 publications with Aldh1a1 and Eye
 Lymph Node Antibodies  >17 publications with Aldh1a1 and Lymph Node
 Prostate Antibodies  >16 publications with Aldh1a1 and Prostate
 Muscle Antibodies  >15 publications with Aldh1a1 and Muscle
 Intestine Antibodies  >14 publications with Aldh1a1 and Intestine
 Testis Antibodies  >14 publications with Aldh1a1 and Testis
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