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anti-ARL1 antibody :: Rabbit anti-Human Aldose Reductase Like Protein 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2027869 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $245 +1 FREE 8GB USB
0.2 mg  /  $370 +1 FREE 8GB USB
1 mg  /  $880 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Aldose Reductase Like Protein 1 (ARL1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Aldose Reductase Like Protein 1 (ARL1)

 Product Gene Name   

anti-ARL1 antibody

[Similar Products]
 Matching Pairs    Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
Antigen: Aldose Reductase Like Protein 1 (MBS2029930)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
APC-CY7 Conjugated Antibody: Aldose Reductase Like Protein 1 (ARL1) (MBS2084840)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
PE Conjugated Antibody: Aldose Reductase Like Protein 1 (ARL1) (MBS2084841)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
APC-CY7 Conjugated Antibody: Aldose Reductase Like Protein 1 (ARL1) (MBS2084842)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
Cy3 Conjugated Antibody: Aldose Reductase Like Protein 1 (ARL1) (MBS2084843)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
FITC Conjugated Antibody: Aldose Reductase Like Protein 1 (ARL1) (MBS2084844)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
HRP Conjugated Antibody: Aldose Reductase Like Protein 1 (ARL1) (MBS2084845)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Aldose Reductase Like Protein 1 (MBS2027869)
Biotin Conjugated Antibody: Aldose Reductase Like Protein 1 (ARL1) (MBS2097098)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- MATFVELSTK AKMPIVGLGT WKSPLGKVKE AVKVAIDAGY RHIDCAYVYQ NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL KLSYLDVYLI HWPQGFKSGD DLFPKDDKGN AIGGKATFLD AWEAMEELVD EGLVKALGVS NFSHFQIEKL LNKPGLKYKP VTNQVECHPY LTQEKLIQYC HSKGITVTAY SPLGSPDRPW AKPEDPSLLE DPKIKEIAAK HKKTAAQVLI RFHIQRNVIV IPKSVTPARI VENIQVFDFK LSDEEMATIL SFNRNWRACN VLQSSHLEDY PFNAEY
 OMIM    U37100 mRNA
 3D Structure    ModBase 3D Structure for O60218
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against ARL1. It has beenselected for its ability to recognize ARL1 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Liquid
 Concentration    200ug/ml (lot specific)
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 Fragment    ARL1 (Met1~Tyr316)
 Organism Species    Homo sapiens (Human)
 Conjugate    No Conjugate
 Immunogen    Recombinant ARL1 (Met1~Tyr316) expressed in E Coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2084842
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-ARL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ARL1 antibody    Knock-Out Validation Antibody
 Applications Tested/Suitable for anti-ARL1 antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

 Application Notes for anti-ARL1 antibody    Western blotting: 0.5-5ug/mL
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
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 Western Blot (WB) Knockout Verification of anti-ARL1 antibody    Knockout Verification: Lane 1: Wild-type HCT116 cell lysate; Lane 2: ARL1 knockout HCT116 cell lysate; Predicted MW: 36kd Observed MW: 33kd Primary Ab: 3ug/ml Rabbit Anti-Human ARL1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-ARL1 antibody Western Blot (WB) Knockout Verification (WB) image
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 Western Blot (WB) of anti-ARL1 antibody    Western Blot; Sample: Lane1: Human HCT116 Cells; Lane2: Human A549 Cells.
anti-ARL1 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-ARL1 antibody    Western Blot; Sample: Recombinant ARL1, Human.
anti-ARL1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ARL1 antibody    DAB staining on IHC-P; Samples: Human Stomach Tissue.
anti-ARL1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ARL1 antibody    DAB staining on IHC-P; Samples: Human Kidney Tissue
anti-ARL1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ARL1 antibody    DAB staining on IHC-P; Samples: Human Lung Cancer Tissue
anti-ARL1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ARL1. It may not necessarily be applicable to this product.
 NCBI GI #    223468663
 NCBI GeneID    57016
 NCBI Accession #    NP_064695.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_020299.4 [Other Products]
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 UniProt Primary Accession #    O60218 [Other Products]
 UniProt Secondary Accession #    O75890; Q6FHF3; Q8IWZ1; A4D1P1 [Other Products]
 UniProt Related Accession #    O60218 [Other Products]
 Molecular Weight    36,020 Da
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 NCBI Official Full Name    aldo-keto reductase family 1 member B10
 NCBI Official Synonym Full Names    aldo-keto reductase family 1 member B10
 NCBI Official Symbol    AKR1B10 [Similar Products]
 NCBI Official Synonym Symbols   
HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12
[Similar Products]
 NCBI Protein Information    aldo-keto reductase family 1 member B10
 UniProt Protein Name    Aldo-keto reductase family 1 member B10
 UniProt Synonym Protein Names   
ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase
 Protein Family    ADP-ribosylation factor-like protein
 UniProt Gene Name    AKR1B10 [Similar Products]
 UniProt Synonym Gene Names    AKR1B11; ARP; hARP; SI reductase [Similar Products]
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 NCBI Summary for ARL1    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ARL1    AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family.

Protein type: Carbohydrate Metabolism - butanoate; Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.-; EC 1.1.1.21; Lipid Metabolism - linoleic acid; Oxidoreductase

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: cytosol; extracellular exosome; lysosome

Molecular Function: aldo-keto reductase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; protein binding; retinal dehydrogenase activity

Biological Process: aldehyde metabolic process; daunorubicin metabolic process; digestion; doxorubicin metabolic process; farnesol catabolic process; retinoid metabolic process; steroid metabolic process
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 Research Articles on ARL1    1. Several antioxidant response elements-like sequences in the 5'-flanking region up to -3282 bp of the AKR1B10 gene plays an important role in AKR1B10 gene regulation by various Nrf2-mediating stimuli.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ARL1 antibodyPathways associated with anti-ARL1 antibody
 Reference Product  PubMed Publications
 ALDH3A1 antibody  >5 publications with ARL1 and ALDH3A1
 GPX2 antibody  >3 publications with ARL1 and GPX2
 CBR1 antibody  >1 publications with ARL1 and CBR1
 EGF antibody  >1 publications with ARL1 and EGF
 CBR3 antibody  >1 publications with ARL1 and CBR3
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Pentose And Glucuronate Interconversions Pathway antibodies  Pentose And Glucuronate Interconversions Pathway Diagram
 Pentose And Glucuronate Interconversions Pathway antibodies  Pentose And Glucuronate Interconversions Pathway Diagram
Diseases associated with anti-ARL1 antibodyOrgans/Tissues associated with anti-ARL1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >64 publications with ARL1 and Neoplasms
 Carcinoma Antibodies  >46 publications with ARL1 and Carcinoma
 Liver Neoplasms Antibodies  >20 publications with ARL1 and Liver Neoplasms
 Lung Neoplasms Antibodies  >20 publications with ARL1 and Lung Neoplasms
 Carcinoma, Hepatocellular Antibodies  >20 publications with ARL1 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >17 publications with ARL1 and Liver Diseases
 Breast Neoplasms Antibodies  >9 publications with ARL1 and Breast Neoplasms
 Colorectal Neoplasms Antibodies  >7 publications with ARL1 and Colorectal Neoplasms
 Liver Cirrhosis Antibodies  >5 publications with ARL1 and Liver Cirrhosis
 Neoplasms, Experimental Antibodies  >5 publications with ARL1 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >36 publications with ARL1 and Lung
 Liver Antibodies  >34 publications with ARL1 and Liver
 Intestine Antibodies  >7 publications with ARL1 and Intestine
 Stomach Antibodies  >5 publications with ARL1 and Stomach
 Uterus Antibodies  >4 publications with ARL1 and Uterus
 Kidney Antibodies  >4 publications with ARL1 and Kidney
 Eye Antibodies  >3 publications with ARL1 and Eye
 Esophagus Antibodies  >2 publications with ARL1 and Esophagus
 Skin Antibodies  >2 publications with ARL1 and Skin
 Brain Antibodies  >2 publications with ARL1 and Brain
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