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anti-a1ACT antibody :: Rabbit anti-Human Alpha-1-Antichymotrypsin (a1ACT) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2003816 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $220 +1 FREE 8GB USB
0.2 mg  /  $320 +1 FREE 8GB USB
1 mg  /  $760 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alpha-1-Antichymotrypsin (a1ACT), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Alpha-1-Antichymotrypsin (a1ACT)

 Product Gene Name   

anti-a1ACT antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below.
MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD GSTSGSGHHH HHHSAGLVPR GSTAIGMKET AAAKFERQHM DSPDLGTLEV LFQGPLGSEF -KKKWVM VPMMSLHHLT IPYFRDEELS CTVVELKYTG NASALFILPD QDKMEEVEAM LLPETLKRWR DSLEFREIGE LYLPKFSISR DYNLNDILLQ LGIEEAFTSK ADLSGITGAR NLAVSQVVHK AVLDVFEEGT EASAATAVKI TLLSALVETR TIVR
 OMIM    K01500 mRNA
 3D Structure    ModBase 3D Structure for P01011
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against a1ACT. It has been selected for its ability to recognize a1ACT in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant a1ACT (Lys235~Arg394) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2050478
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-a1ACT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-a1ACT antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-a1ACT antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-a1ACT antibody    (Figure. Western Blot; Sample: Recombinant a1ACT, Human.)
anti-a1ACT antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-a1ACT antibody    (Figure.DAB staining on IHC-P. Samples: Human Tissue)
anti-a1ACT antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for a1ACT. It may not necessarily be applicable to this product.
 NCBI GI #    50659080
 NCBI GeneID    12
 NCBI Accession #    NP_001076.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001085.4 [Other Products]
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 UniProt Primary Accession #    P01011 [Other Products]
 UniProt Secondary Accession #    Q13703; Q2TU87; Q2TU88; Q59GP9; Q6LBY8; Q6LDT7; Q6NSC9; Q8N177; Q96DW8; Q9UC47; B3KVQ7 [Other Products]
 UniProt Related Accession #    P01011 [Other Products]
 Molecular Weight    10,717 Da
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 NCBI Official Full Name    alpha-1-antichymotrypsin
 NCBI Official Synonym Full Names    serpin family A member 3
 NCBI Official Symbol    SERPINA3 [Similar Products]
 NCBI Official Synonym Symbols   
ACT; AACT; GIG24; GIG25
[Similar Products]
 NCBI Protein Information    alpha-1-antichymotrypsin
 UniProt Protein Name    Alpha-1-antichymotrypsin
 UniProt Synonym Protein Names   
Cell growth-inhibiting gene 24/25 protein; Serpin A3
 UniProt Gene Name    SERPINA3 [Similar Products]
 UniProt Synonym Gene Names    AACT; ACT [Similar Products]
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 NCBI Summary for a1ACT    The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for a1ACT    Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
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 Research Articles on a1ACT    1. evaluation of serum proteins reveals that SERPINA1, SERPINA3 and SERPINC1 could be useful to discriminate healthy from colorectal carcinoma patients with a high sensitivity and specificity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-a1ACT antibodyPathways associated with anti-a1ACT antibody
 Reference Product  PubMed Publications
 MMP1 antibody  >1 publications with a1ACT and MMP1
 APP antibody  >1 publications with a1ACT and APP
 CTSG antibody  >1 publications with a1ACT and CTSG
 Products by Pathway  Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with anti-a1ACT antibodyOrgans/Tissues associated with anti-a1ACT antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with a1ACT and Neoplasms
 Inflammation Antibodies  >13 publications with a1ACT and Inflammation
 Cardiovascular Diseases Antibodies  >12 publications with a1ACT and Cardiovascular Diseases
 Mental Disorders Antibodies  >5 publications with a1ACT and Mental Disorders
 Hypertension Antibodies  >4 publications with a1ACT and Hypertension
 Necrosis Antibodies  >4 publications with a1ACT and Necrosis
 Liver Diseases Antibodies  >4 publications with a1ACT and Liver Diseases
 Heart Diseases Antibodies  >3 publications with a1ACT and Heart Diseases
 Heart Failure Antibodies  >1 publications with a1ACT and Heart Failure
 Seizures Antibodies  >1 publications with a1ACT and Seizures
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with a1ACT and Brain
 Liver Antibodies  >7 publications with a1ACT and Liver
 Uterus Antibodies  >4 publications with a1ACT and Uterus
 Lung Antibodies  >2 publications with a1ACT and Lung
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