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anti-AFP antibody :: Rabbit Alpha 1 Fetoprotein Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS540216
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alpha 1 Fetoprotein (AFP), Polyclonal Antibody

 Also Known As   

Alpha 1 Fetoprotein Antibody

 Product Synonym Names    AFP; Alpha fetoglobulin; FETA; Hereditary persistence of alpha fetoprotein; HPAFP antibody
 Product Gene Name   

anti-AFP antibody

[Similar Products]
 Antibody/Peptide Pairs    Alpha 1 Fetoprotein peptide (MBS542339) is used for blocking the activity of Alpha 1 Fetoprotein antibody (MBS540216)
 Matching Pairs    Antibody: Alpha 1 Fetoprotein (MBS540216)
Positive Control: Alpha 1 Fetoprotein (MBS542510)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    104150
 3D Structure    ModBase 3D Structure for P02771
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Monkey, Rat
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 Form/Format    Affinity Purified
 Concentration    0.68 ug/ul in antibody stabilization buffer (lot specific)
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 Immunogen    Full length native protein (purified) corresponding to Human alpha 1 Fetoprotein. Purified human alpha 1 Fetoprotein.
 Expression    Plasma. Synthesized by fetal liver and yolk sac.
 Molecular Function    Copper, Nickel; metal-binding
 Structure    Dimeric and trimeric forms have been found in addition to the monomeric form
 Subcellular Location    Secreted
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-AFP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-AFP antibody

   Affinity Purified alpha-fetoprotein Antibody
Binds copper, nickel, fatty acids, bilirubin.
 Product Categories/Family for anti-AFP antibody    Primary Antibodies; Cardiology; Serum Proteins; Alpha 1 Fetoprotein Antibody
 Applications Tested/Suitable for anti-AFP antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

 Application Notes for anti-AFP antibody    Dot Blot: 1:10,000
ELISA: 1:10,000
Immunohistochemistry: 1:200
Immunoprecipitation: 1:200
Western Blot: 1:500
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 Western Blot (WB) of anti-AFP antibody    anti-AFP antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-AFP antibody    anti-AFP antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-AFP antibody    anti-AFP antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for AFP. It may not necessarily be applicable to this product.
 NCBI GI #    178236
 NCBI GeneID    174
 NCBI Accession #    AAB58754.1 [Other Products]
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 UniProt Primary Accession #    P02771 [Other Products]
 UniProt Secondary Accession #    B2RBU3 [Other Products]
 UniProt Related Accession #    P02771 [Other Products]
 Molecular Weight    Predicted: 69 kDa [Similar Products]
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 NCBI Official Full Name    alpha-fetoprotein
 NCBI Official Synonym Full Names    alpha fetoprotein
 NCBI Official Symbol    AFP [Similar Products]
 NCBI Official Synonym Symbols   
AFPD; FETA; HPAFP
[Similar Products]
 NCBI Protein Information    alpha-fetoprotein
 UniProt Protein Name    Alpha-fetoprotein
 UniProt Synonym Protein Names   
Alpha-1-fetoprotein; Alpha-fetoglobulin
 Protein Family    Alpha-fetoprotein
 UniProt Gene Name    AFP [Similar Products]
 UniProt Synonym Gene Names    HPAFP [Similar Products]
 UniProt Entry Name    FETA_HUMAN
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 NCBI Summary for AFP    This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AFP    AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: cytoplasm; extracellular space

Molecular Function: metal ion binding

Biological Process: liver development; organ regeneration; ovulation from ovarian follicle; pancreas development; progesterone metabolic process; response to organic substance; transport

Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of
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 Research Articles on AFP    1. AFP has a role in radiologic response to combined radiotherapy and transarterial chemoembolization for hepatocellular carcinoma with portal vein tumor thrombus
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AFP antibodyPathways associated with anti-AFP antibody
 Reference Product  PubMed Publications
 JUN antibody  >1066 publications with AFP and JUN
 MYC antibody  >58 publications with AFP and MYC
 FOXA1 antibody  >14 publications with AFP and FOXA1
 TP53 antibody  >13 publications with AFP and TP53
 CEBPA antibody  >9 publications with AFP and CEBPA
 ZFHX3 antibody  >9 publications with AFP and ZFHX3
 FOXA3 antibody  >5 publications with AFP and FOXA3
 FOXM1 antibody  >4 publications with AFP and FOXM1
 UBC antibody  >4 publications with AFP and UBC
 EFNA1 antibody  >2 publications with AFP and EFNA1
 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
Diseases associated with anti-AFP antibodyOrgans/Tissues associated with anti-AFP antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >4451 publications with AFP and Liver Diseases
 Liver Neoplasms Antibodies  >4305 publications with AFP and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4184 publications with AFP and Carcinoma, Hepatocellular
 Nervous System Diseases Antibodies  >1349 publications with AFP and Nervous System Diseases
 Liver Cirrhosis Antibodies  >1270 publications with AFP and Liver Cirrhosis
 Neoplasm Metastasis Antibodies  >596 publications with AFP and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >455 publications with AFP and Neoplasms, Experimental
 Liver Neoplasms, Experimental Antibodies  >392 publications with AFP and Liver Neoplasms, Experimental
 Lung Neoplasms Antibodies  >363 publications with AFP and Lung Neoplasms
 Stomach Neoplasms Antibodies  >350 publications with AFP and Stomach Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5460 publications with AFP and Liver
 Blood Antibodies  >4009 publications with AFP and Blood
 Vascular Antibodies  >692 publications with AFP and Vascular
 Lung Antibodies  >423 publications with AFP and Lung
 Brain Antibodies  >350 publications with AFP and Brain
 Embryonic Tissue Antibodies  >303 publications with AFP and Embryonic Tissue
 Muscle Antibodies  >231 publications with AFP and Muscle
 Kidney Antibodies  >182 publications with AFP and Kidney
 Placenta Antibodies  >174 publications with AFP and Placenta
 Heart Antibodies  >108 publications with AFP and Heart
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