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anti-ANGPTL8 antibody :: Rabbit anti-Mouse Angiopoietin Like Protein 8 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2027267 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $195 +1 FREE 8GB USB
0.1 mg  /  $250 +1 FREE 8GB USB
0.2 mg  /  $380 +1 FREE 8GB USB
1 mg  /  $905 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Angiopoietin Like Protein 8 (ANGPTL8), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8)

 Product Gene Name   

anti-ANGPTL8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q8R1L8
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a rabbit polyclonal antibody raised against ANGPTL8. It has beenselected for its ability to recognize ANGPTL8 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as a solution form in PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preperation
 Traits    Liquid
 Immunogen    Recombinant ANGPTL8 (Val16~Ala198) expressed in E.coli
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2085762
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 Preparation and Storage    Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
 Supply Chain Verification    Manufactured in an a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-ANGPTL8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ANGPTL8 antibody   

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM

 Application Notes for anti-ANGPTL8 antibody    Western Blotting: 0.5-2 ug/ml
Immunocytochemistry in formalin fixed cells: 5-20 ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20 ug/ml
Immunohistochemistry in paraffin section: 5-20 ug/ml
Enzyme linked Immunosorbent Assay: 0.05-2 ug/ml

Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-ANGPTL8 antibody    (Figure. Western Blot; Sample: Recombinant ANGPTL8, Mouse.)
anti-ANGPTL8 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ANGPTL8 antibody    (Used in DAB staining on formalin fixed paraffin-embedded Liver tissue)
anti-ANGPTL8 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ANGPTL8. It may not necessarily be applicable to this product.
 NCBI GI #    124301204
 NCBI GeneID    624219
 NCBI Accession #    NP_001074409.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001080940.1 [Other Products]
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 UniProt Primary Accession #    Q8R1L8 [Other Products]
 UniProt Related Accession #    Q8R1L8 [Other Products]
 Molecular Weight    22,063 Da
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 NCBI Official Full Name    angiopoietin-like protein 8
 NCBI Official Synonym Full Names    angiopoietin-like 8
 NCBI Official Symbol    Angptl8 [Similar Products]
 NCBI Official Synonym Symbols   
Rifl; Gm6484; EG624219
[Similar Products]
 NCBI Protein Information    angiopoietin-like protein 8
 UniProt Protein Name    Angiopoietin-like protein 8
 UniProt Synonym Protein Names   
Betatrophin
 Protein Family    Angiopoietin-like protein
 UniProt Gene Name    Angptl8 [Similar Products]
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 UniProt Comments for ANGPTL8    EG624219: Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. In response to food intake. Interacts with ANGPTL3

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9|9 A3

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cell maturation; cellular lipid metabolic process; fat cell differentiation; glucose metabolic process; lipid metabolic process; negative regulation of lipoprotein lipase activity; regulation of lipid metabolic process; regulation of lipoprotein metabolic process
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 Research Articles on ANGPTL8    1. knock-down of Angptl8 in adipocytes suggests that the protein acts to inhibit intracellular lipolysis, analogous to its activity in the circulation. Depletion of Angptl8 results in an altered cellular phospholipid composition. The findings identify Angptl8 as a central insulin-regulated controller of adipocyte lipid metabolism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-ANGPTL8 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with ANGPTL8 and Liver
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