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anti-ANXA1 antibody :: Rabbit anti-Human Annexin A1 (ANXA1) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2001850 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-ANXA1 antibody
Unit / Price
0.01 mg  /  $115 +1 FREE 8GB USB
0.02 mg  /  $135 +1 FREE 8GB USB
0.05 mg  /  $190 +1 FREE 8GB USB
0.1 mg  /  $245 +1 FREE 8GB USB
0.2 mg  /  $370 +1 FREE 8GB USB
1 mg  /  $880 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Annexin A1 (ANXA1), Polyclonal Antibody

 Also Known As   

Biotin-Linked Antibody to Annexin A1 (ANXA1)

 Product Gene Name   

anti-ANXA1 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Annexin A1 (ANXA1) (MBS2003271)
Biotin Conjugated Antibody: Annexin A1 (ANXA1) (MBS2001850)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 9; NC_000009.11 (75766721..75785309). Location: 9q21.13
 OMIM    151690
 3D Structure    ModBase 3D Structure for P04083
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against ANXA1 conjugated to biotin. It has been selected for its ability to recognize ANXA1 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-ANXA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-ANXA1 antibody    Biotin Antibody
 Applications Tested/Suitable for anti-ANXA1 antibody   

Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)

 Application Notes for anti-ANXA1 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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NCBI/Uniprot data below describe general gene information for ANXA1. It may not necessarily be applicable to this product.
 NCBI GI #    4502101
 NCBI GeneID    301
 NCBI Accession #    NP_000691.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000700.1 [Other Products]
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 UniProt Primary Accession #    P04083 [Other Products]
 UniProt Related Accession #    P04083 [Other Products]
 Molecular Weight    38,714 Da
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 NCBI Official Full Name    annexin A1
 NCBI Official Synonym Full Names    annexin A1
 NCBI Official Symbol    ANXA1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    annexin A1; p35; annexin-1; calpactin-2; calpactin II; lipocortin I; chromobindin-9; annexin I (lipocortin I); phospholipase A2 inhibitory protein
 UniProt Protein Name    Annexin A1
 UniProt Synonym Protein Names   
Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35
 Protein Family    Annexin
 UniProt Gene Name    ANXA1 [Similar Products]
 UniProt Synonym Gene Names    ANX1; LPC1 [Similar Products]
 UniProt Entry Name    ANXA1_HUMAN
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 NCBI Summary for ANXA1    This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
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 UniProt Comments for ANXA1    ANXA1: a calcium/phospholipid-binding protein with which promotes membrane fusion and is involved in endocytosis. Has anti-inflammatory properties and inhibits phospholipase A2 activity. Accumulates on internalized vesicles after EGF-stimulated endocytosis, suggesting that it may be required for a late stage in inward vesiculation. Phosphorylated by PKC, EGFR and Chak1. Phosphorylation results in loss of the inhibitory activity. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding; Lipid-binding

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: extracellular space; protein complex; focal adhesion; mast cell granule; cell surface; basolateral plasma membrane; extracellular region; cornified envelope; cilium; mitochondrial membrane; cytoplasm; plasma membrane; nucleus; sarcolemma; vesicle; endosome

Molecular Function: protein binding, bridging; protein binding; protein homodimerization activity; single-stranded RNA binding; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; double-stranded DNA-dependent ATPase activity; phospholipid binding; calcium ion binding; structural molecule activity; calcium-dependent protein binding; helicase activity; single-stranded DNA binding; receptor binding

Biological Process: prostate gland development; response to drug; response to peptide hormone stimulus; positive regulation of neutrophil apoptosis; gliogenesis; positive regulation of vesicle fusion; alpha-beta T cell differentiation; signal transduction; arachidonic acid secretion; neutrophil homeostasis; endocrine pancreas development; response to estradiol stimulus; DNA duplex unwinding; regulation of cell proliferation; keratinocyte differentiation; cell surface receptor linked signal transduction; insulin secretion; DNA strand renaturation; peptide cross-linking; cell motility; inflammatory response; positive regulation of prostaglandin biosynthetic process; negative regulation of apoptosis; response to X-ray
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 Research Articles on ANXA1    1. Suggest annexin A1 may serve as a new immunohistochemical marker of cholangiocarcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ANXA1 antibodyPathways associated with anti-ANXA1 antibody
 Reference Product  PubMed Publications
 FPR2 antibody  >21 publications with ANXA1 and FPR2
 POMC antibody  >11 publications with ANXA1 and POMC
 FPR1 antibody  >10 publications with ANXA1 and FPR1
 S100A11 antibody  >5 publications with ANXA1 and S100A11
 FPR3 antibody  >2 publications with ANXA1 and FPR3
 S100A6 antibody  >2 publications with ANXA1 and S100A6
 PLA2G1B antibody  >1 publications with ANXA1 and PLA2G1B
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies  Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
Diseases associated with anti-ANXA1 antibodyOrgans/Tissues associated with anti-ANXA1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >88 publications with ANXA1 and Neoplasms
 Inflammation Antibodies  >66 publications with ANXA1 and Inflammation
 Carcinoma Antibodies  >49 publications with ANXA1 and Carcinoma
 Neoplasm Metastasis Antibodies  >16 publications with ANXA1 and Neoplasm Metastasis
 Brain Diseases Antibodies  >15 publications with ANXA1 and Brain Diseases
 Carcinoma, Squamous Cell Antibodies  >13 publications with ANXA1 and Carcinoma, Squamous Cell
 Necrosis Antibodies  >12 publications with ANXA1 and Necrosis
 Pain Antibodies  >9 publications with ANXA1 and Pain
 Fibrosis Antibodies  >8 publications with ANXA1 and Fibrosis
 Stomach Diseases Antibodies  >7 publications with ANXA1 and Stomach Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >81 publications with ANXA1 and Blood
 Brain Antibodies  >26 publications with ANXA1 and Brain
 Lung Antibodies  >21 publications with ANXA1 and Lung
 Vascular Antibodies  >19 publications with ANXA1 and Vascular
 Pituitary Gland Antibodies  >13 publications with ANXA1 and Pituitary Gland
 Liver Antibodies  >13 publications with ANXA1 and Liver
 Lymph Node Antibodies  >11 publications with ANXA1 and Lymph Node
 Muscle Antibodies  >9 publications with ANXA1 and Muscle
 Stomach Antibodies  >8 publications with ANXA1 and Stomach
 Bone Antibodies  >7 publications with ANXA1 and Bone
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