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anti-APOA4 antibody :: Rabbit anti-Mouse Apolipoprotein A4 (APOA4) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2002143 (3 units are in stock [0.1 mg] for immediate shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Apolipoprotein A4 (APOA4), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Apolipoprotein A4 (APOA4)

 Product Gene Name   

anti-APOA4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P06728
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a Rabbit polyclonal antibody raised against APOA4. It has been selected for its ability to recognize APOA4 in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant APOA4 (Gln299~Ala369) expressed in E.coli
    
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2061220
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for two years.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-APOA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-APOA4 antibody   

WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM

 Application Notes for anti-APOA4 antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml

Optimal working dilutions must be determined by end user
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 Western Blot (WB) of anti-APOA4 antibody    (Western Blot; Sample: Mouse Lung lysate; Primary Ab: 1ug/ml Rabbit Anti-Mouse APOA4 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
anti-APOA4 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-APOA4 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-APOA4 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-APOA4 antibody    (Used in DAB staining on formalin fixed paraffin-embedded Bowels tissue)
anti-APOA4 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for APOA4. It may not necessarily be applicable to this product.
 NCBI GI #    110347473
 NCBI GeneID    11808
 NCBI Accession #    NP_031494.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_007468.2 [Other Products]
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 UniProt Primary Accession #    P06728 [Other Products]
 UniProt Secondary Accession #    Q91XF8 [Other Products]
 UniProt Related Accession #    P06728 [Other Products]
 Molecular Weight    45,029 Da
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 NCBI Official Full Name    apolipoprotein A-IV
 NCBI Official Synonym Full Names    apolipoprotein A-IV
 NCBI Official Symbol    Apoa4 [Similar Products]
 NCBI Official Synonym Symbols   
Apoa-4
[Similar Products]
 NCBI Protein Information    apolipoprotein A-IV
 UniProt Protein Name    Apolipoprotein A-IV
 UniProt Synonym Protein Names   
Apolipoprotein A4
 Protein Family    Apolipoprotein
 UniProt Gene Name    Apoa4 [Similar Products]
 UniProt Synonym Gene Names    Apo-AIV; ApoA-IV [Similar Products]
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 UniProt Comments for APOA4    APOA4: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Synthesized primarily in the intestine and secreted in plasma. Belongs to the apolipoprotein A1/A4/E family.

Protein type: Cell adhesion; Endoplasmic reticulum; Lipid-binding; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9 A5.2|9 25.36 cM

Cellular Component: cell surface; chylomicron; extracellular matrix; extracellular region; extracellular space

Molecular Function: antioxidant activity; cholesterol binding; cholesterol transporter activity; copper ion binding; lipid binding; phosphatidylcholine binding; protein homodimerization activity

Biological Process: cholesterol biosynthetic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; hydrogen peroxide catabolic process; innate immune response in mucosa; leukocyte adhesion; lipid homeostasis; lipid transport; lipoprotein metabolic process; multicellular organismal lipid catabolic process; neuron projection regeneration; phosphatidylcholine metabolic process; phospholipid efflux; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity; protein-lipid complex assembly; regulation of cholesterol transport; regulation of intestinal cholesterol absorption; removal of superoxide radicals; response to lipid hydroperoxide; reverse cholesterol transport; transport; triglyceride catabolic process
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 Research Articles on APOA4    1. This study uncovers an anti-sense lncRNA (APOA4-AS), which is co-expressed with APOA4, and concordantly and specifically regulates APOA4 expression both in vitro and in vivo with the involvement of HuR.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-APOA4 antibodyDiseases associated with anti-APOA4 antibody
 Products by Pathway  Pathway Diagram
 Chylomicron-mediated Lipid Transport Pathway antibodies  Chylomicron-mediated Lipid Transport Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Fat-soluble Vitamins Pathway antibodies  Metabolism Of Fat-soluble Vitamins Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Retinoid Metabolism And Transport Pathway antibodies  Retinoid Metabolism And Transport Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >28 publications with APOA4 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >16 publications with APOA4 and Atherosclerosis
 Heart Diseases Antibodies  >15 publications with APOA4 and Heart Diseases
 Dyslipidemias Antibodies  >14 publications with APOA4 and Dyslipidemias
 Hyperlipidemias Antibodies  >12 publications with APOA4 and Hyperlipidemias
 Fatty Liver Antibodies  >8 publications with APOA4 and Fatty Liver
 Inflammation Antibodies  >7 publications with APOA4 and Inflammation
 Liver Diseases Antibodies  >6 publications with APOA4 and Liver Diseases
 Immune System Diseases Antibodies  >4 publications with APOA4 and Immune System Diseases
 Brain Diseases Antibodies  >3 publications with APOA4 and Brain Diseases
Organs/Tissues associated with anti-APOA4 antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >27 publications with APOA4 and Liver
 Heart Antibodies  >16 publications with APOA4 and Heart
 Intestine Antibodies  >10 publications with APOA4 and Intestine
 Muscle Antibodies  >4 publications with APOA4 and Muscle
 Kidney Antibodies  >2 publications with APOA4 and Kidney
 Pancreas Antibodies  >2 publications with APOA4 and Pancreas
 Stomach Antibodies  >1 publications with APOA4 and Stomach
 Ovary Antibodies  >1 publications with APOA4 and Ovary
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