CAA28583.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
apolipoprotein
NCBI Official Synonym Full Names
apolipoprotein A-II
NCBI Protein Information
apolipoprotein A-II; apolipoprotein A2; OTTHUMP00000032244
UniProt Protein Name
Apolipoprotein A-II
UniProt Synonym Protein Names
Apolipoprotein A2
UniProt Entry Name
APOA2_HUMAN
NCBI Summary for APOA2
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq]
UniProt Comments for APOA2
Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP. Ref.14 Ref.15 Ref.18
Subcellular location: Secreted.
Tissue specificity: Plasma; synthesized in the liver and intestine.
Post-translational modification: Phosphorylation sites are present in the extracelllular medium.
Sequence similarities: Belongs to the apolipoprotein A2 family.
Mass spectrometry: Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.16Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.16Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.16Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with apolipoprotein A-II(1-76). Ref.16Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.16Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.16
Research Articles on APOA2
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Products associated with anti-APOA2 antibody
Pathways associated with anti-APOA2 antibody
Diseases associated with anti-APOA2 antibody
Organs/Tissues associated with anti-APOA2 antibody
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