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anti-AQP1 antibody :: Rabbit Aquaporin 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8240979
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Aquaporin 1 (AQP1), Polyclonal Antibody

 Also Known As   

Anti-Aquaporin 1 Antibody

 Product Synonym Names    CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
 Product Gene Name   

anti-AQP1 antibody

[Similar Products]
 Antibody/Peptide Pairs    Aquaporin 1 peptide (MBS8230038) is used for blocking the activity of Aquaporin 1 antibody (MBS8240979)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    107776
 3D Structure    ModBase 3D Structure for P29972
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Monkey
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 Specificity    Recognizes endogenous levels of Aquaporin 1 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Aquaporin 1. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-AQP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-AQP1 antibody

   Rabbit polyclonal antibody to Aquaporin 1
 Applications Tested/Suitable for anti-AQP1 antibody   

Western Blot (WB)

 Application Notes for anti-AQP1 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-AQP1 antibody    Western blot analysis of Aquaporin 1 expression in A549 (A), mouse liver (B), rat liver (C) whole cell lysates.
anti-AQP1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for AQP1. It may not necessarily be applicable to this product.
 NCBI GI #    297307116
 NCBI GeneID    358
 NCBI Accession #    NP_001171989.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001185060.1 [Other Products]
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 UniProt Primary Accession #    P29972 [Other Products]
 UniProt Secondary Accession #    Q8TBI5; Q8TDC1; B5BU39; E7EM69; E9PC21; F5GY19 [Other Products]
 UniProt Related Accession #    P29972 [Other Products]
 Molecular Weight    16,677 Da
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 NCBI Official Full Name    aquaporin-1 isoform 2
 NCBI Official Synonym Full Names    aquaporin 1 (Colton blood group)
 NCBI Official Symbol    AQP1 [Similar Products]
 NCBI Official Synonym Symbols   
CO; CHIP28; AQP-CHIP
[Similar Products]
 NCBI Protein Information    aquaporin-1
 UniProt Protein Name    Aquaporin-1
 UniProt Synonym Protein Names   
Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
 UniProt Gene Name    AQP1 [Similar Products]
 UniProt Synonym Gene Names    CHIP28; AQP-1 [Similar Products]
 UniProt Entry Name    AQP1_HUMAN
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 NCBI Summary for AQP1    Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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 UniProt Comments for AQP1    AQP1: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, aquaporin family

Chromosomal Location of Human Ortholog: 7p14

Cellular Component: nuclear membrane; brush border membrane; integral to plasma membrane; basolateral plasma membrane; apical part of cell; apical plasma membrane; cytoplasm; basal plasma membrane; plasma membrane; nerve terminal; nucleus; sarcolemma; brush border

Molecular Function: protein binding; potassium channel activity; ephrin receptor binding; water transporter activity; ammonium transmembrane transporter activity; intracellular cGMP activated cation channel activity; potassium ion transmembrane transporter activity; glycerol transmembrane transporter activity; transmembrane transporter activity; water channel activity; nitric oxide transporter activity; glycerol channel activity

Biological Process: cGMP biosynthetic process; glycerol transport; cerebrospinal fluid secretion; wound healing; carbon dioxide transport; cellular response to stress; water transport; negative regulation of caspase activity; pancreatic juice secretion; sensory perception of pain; positive regulation of saliva secretion; odontogenesis; positive regulation of fibroblast proliferation; nitric oxide transport; hyperosmotic salinity response; bicarbonate transport; cellular homeostasis; multicellular organismal water homeostasis; transmembrane transport; potassium ion transport; lateral ventricle development; lipid digestion; response to drug; cellular water homeostasis; secretory granule organization and biogenesis; glomerular filtration; ammonium transport; positive regulation of angiogenesis; renal water transport; camera-type eye morphogenesis; response to estrogen stimulus; adrenocorticotropin hormone secretion; establishment and/or maintenance of actin cytoskeleton polarity; renal water homeostasis; cell volume homeostasis; negative regulation of apoptosis

Disease: Blood Group--colton
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 Research Articles on AQP1    1. Study found a significant correlation between AQP1, AQP3, and AQP5 overexpression and lymph node metastasis in patients with surgically resected colon cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AQP1 antibodyPathways associated with anti-AQP1 antibody
 Reference Product  PubMed Publications
 AQP2 antibody  >251 publications with AQP1 and AQP2
 AVP antibody  >19 publications with AQP1 and AVP
 TNF antibody  >14 publications with AQP1 and TNF
 UHMK1 antibody  >1 publications with AQP1 and UHMK1
 HBB antibody  >1 publications with AQP1 and HBB
 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway antibodies  Erythrocytes Take Up Carbon Dioxide And Release Oxygen Pathway Diagram
 Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway antibodies  Erythrocytes Take Up Oxygen And Release Carbon Dioxide Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 O2/CO2 Exchange In Erythrocytes Pathway antibodies  O2/CO2 Exchange In Erythrocytes Pathway Diagram
 Passive Transport By Aquaporins Pathway antibodies  Passive Transport By Aquaporins Pathway Diagram
 Proximal Tubule Bicarbonate Reclamation Pathway antibodies  Proximal Tubule Bicarbonate Reclamation Pathway Diagram
 Proximal Tubule Bicarbonate Reclamation Pathway antibodies  Proximal Tubule Bicarbonate Reclamation Pathway Diagram
Diseases associated with anti-AQP1 antibodyOrgans/Tissues associated with anti-AQP1 antibody
 Disease Name  Pubmed Publications
 Edema Antibodies  >170 publications with AQP1 and Edema
 Kidney Diseases Antibodies  >130 publications with AQP1 and Kidney Diseases
 Disease Models, Animal Antibodies  >107 publications with AQP1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >105 publications with AQP1 and Nervous System Diseases
 Lung Diseases Antibodies  >60 publications with AQP1 and Lung Diseases
 Carcinoma Antibodies  >52 publications with AQP1 and Carcinoma
 Inflammation Antibodies  >44 publications with AQP1 and Inflammation
 Fibrosis Antibodies  >40 publications with AQP1 and Fibrosis
 Hypertension Antibodies  >33 publications with AQP1 and Hypertension
 Liver Diseases Antibodies  >27 publications with AQP1 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >403 publications with AQP1 and Kidney
 Brain Antibodies  >208 publications with AQP1 and Brain
 Vascular Antibodies  >187 publications with AQP1 and Vascular
 Lung Antibodies  >157 publications with AQP1 and Lung
 Eye Antibodies  >140 publications with AQP1 and Eye
 Muscle Antibodies  >66 publications with AQP1 and Muscle
 Liver Antibodies  >61 publications with AQP1 and Liver
 Heart Antibodies  >59 publications with AQP1 and Heart
 Mouth Antibodies  >54 publications with AQP1 and Mouth
 Intestine Antibodies  >48 publications with AQP1 and Intestine
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