NP_037041.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
aquaporin-2
NCBI Official Synonym Full Names
aquaporin 2 (collecting duct)
NCBI Protein Information
aquaporin-2; AQP-CD; WCH-CD; aquaporin-CD; ADH water channel; collecting duct water channel protein; water channel protein for renal collecting duct
UniProt Protein Name
Aquaporin-2
UniProt Synonym Protein Names
ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct
UniProt Synonym Gene Names
UniProt Entry Name
AQP2_RAT
NCBI Summary for Aqp2
water channel protein involved in water reabsorption and vasopressin regulation in kidney collecting duct cells; mutation is linked to nephrogenic diabetes insipidous (NDI) [RGD, Feb 2006]
UniProt Comments for Aqp2
AQP2: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Expressed in renal collecting tubules. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Transporter; Channel, misc.; Membrane protein, multi-pass; Membrane protein, integral; Transporter, aquaporin family
Cellular Component: cytoplasmic vesicle membrane; protein complex; rough endoplasmic reticulum; clathrin-coated vesicle; integral to plasma membrane; basolateral plasma membrane; lysosome; early endosome; trans-Golgi network; recycling endosome; transport vesicle; membrane; apical plasma membrane; cytoplasm; plasma membrane; cytoplasmic vesicle
Molecular Function: protein binding; water transporter activity; glycerol transmembrane transporter activity; actin binding; water channel activity; PDZ domain binding; glycerol channel activity
Biological Process: actin filament depolymerization; glycerol transport; cellular water homeostasis; response to glucagon stimulus; apoptosis; water transport; response to lithium ion; response to hormone stimulus; response to lipopolysaccharide; cellular response to water deprivation; female pregnancy; response to salt stress; water homeostasis; response to starvation; hyperosmotic response; renal water transport; response to calcium ion; cell volume homeostasis; positive regulation of calcium ion transport; transmembrane transport; response to water deprivation; aging
Product References and Citations for anti-Aqp2 antibody
1. Gonen T., Walz T. (2006) Q. Rev. Biophys. 39(4): 361-
Research Articles on Aqp2
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Products associated with anti-Aqp2 antibody
Pathways associated with anti-Aqp2 antibody
Diseases associated with anti-Aqp2 antibody
Organs/Tissues associated with anti-Aqp2 antibody
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