NP_033792.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
77,967 Da
NCBI Official Full Name
arachidonate 5-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 5-lipoxygenase
NCBI Official Synonym Symbols
5LO; 5LX; 5-LO; 5-LOX; AI850497; F730011J02 [Similar Products]
NCBI Protein Information
arachidonate 5-lipoxygenase
UniProt Protein Name
Arachidonate 5-lipoxygenase
UniProt Synonym Gene Names
UniProt Comments for ALOX5
5-LO: arachidonate 5-lipoxygenase. Arachidonic acid promotes its phosphorylation by p38 MAPK-regulated MAPKAP kinases. Upregulated in glioblastoma multiforme and colon, pancreatic and bladder cancer.
Protein type: EC 1.13.11.34; Lipid Metabolism - arachidonic acid; Lipid Metabolism - linoleic acid; Nuclear envelope; Oxidoreductase
Chromosomal Location of Human Ortholog: 6 E3|6 53.79 cM
Cellular Component: cytoplasm; cytosol; dendrite; extracellular space; membrane; nuclear envelope; nuclear envelope lumen; nuclear matrix; nuclear membrane; nucleoplasm; nucleus; sarcolemma
Molecular Function: arachidonate 5-lipoxygenase activity; dioxygenase activity; iron ion binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding
Biological Process: acute inflammatory response; arachidonic acid metabolic process; inflammatory response; leukotriene biosynthetic process; leukotriene metabolic process; leukotriene production involved in inflammatory response; lipoxygenase pathway; positive regulation of vasoconstriction; sensory perception of pain
Research Articles on ALOX5
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Products associated with anti-ALOX5 antibody
Pathways associated with anti-ALOX5 antibody
Diseases associated with anti-ALOX5 antibody
Organs/Tissues associated with anti-ALOX5 antibody
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