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anti-ARSD antibody :: Goat Arylsulfatase D Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421978
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Arylsulfatase D (ARSD), Polyclonal Antibody

 Also Known As   

Goat anti-Arylsulfatase D Antibody

 Product Synonym Names    arylsulfatase D; ARSD; arylsulfatase D antibody; ARSD antibody; Arylsulfatase D; Arylsulfatase D
 Product Gene Name   

anti-ARSD antibody

[Similar Products]
 Antibody/Peptide Pairs    Arylsulfatase D peptide (MBS425128) is used for blocking the activity of Arylsulfatase D antibody (MBS421978)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    DASNGYRALQ WNA
 OMIM    300002
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-DASNGYRALQWNA, from the internal region of the protein sequence according to NP_001660.2; NP_033667.2.
 Epitope    Internal region
 Note    This antibody is expected to recognise both reported isoforms (NP_001660.2; NP_033667.2)
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-ARSD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ARSD antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-ARSD antibody    Peptide ELISA: Antibody detection limit dilution 1: 16000.
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 Western Blot (WB) of anti-ARSD antibody    (0.3ug/ml) staining of A459 lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
anti-ARSD antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ARSD. It may not necessarily be applicable to this product.
 NCBI GI #    71852584
 NCBI GeneID    414
 NCBI Accession #    NP_001660.2 [Other Products]
 NCBI Related Accession #    NP_033667.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001669.3 [Other Products]
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 UniProt Secondary Accession #    Q9UHJ8 [Other Products]
 UniProt Related Accession #    P51689 [Other Products]
 Molecular Weight    54,934 Da
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 NCBI Official Full Name    arylsulfatase D isoform alpha
 NCBI Official Synonym Full Names    arylsulfatase D
 NCBI Official Symbol    ARSD [Similar Products]
 NCBI Official Synonym Symbols   
ASD
[Similar Products]
 NCBI Protein Information    arylsulfatase D
 UniProt Protein Name    Arylsulfatase D
 Protein Family    Arylsulfatase
 UniProt Gene Name    ARSD [Similar Products]
 UniProt Synonym Gene Names    ASD [Similar Products]
 UniProt Entry Name    ARSD_HUMAN
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 NCBI Summary for ARSD    The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y. [provided by RefSeq, Jul 2011]
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 UniProt Comments for ARSD    ARSD: is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y. [provided by RefSeq, Jul 2011]

Protein type: EC 3.1.6.-; Hydrolase

Chromosomal Location of Human Ortholog: Xp22.3

Cellular Component: endoplasmic reticulum lumen; lysosome

Molecular Function: arylsulfatase activity; metal ion binding

Biological Process: glycosphingolipid metabolic process; post-translational protein modification
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 Research Articles on ARSD    1. ARSD protein level and IGVH were independently associated with the need for therapy of chronic lymphocytic leukemia patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ARSD antibodyDiseases associated with anti-ARSD antibody
 Products by Pathway  Pathway Diagram
 Estrogen Metabolism Pathway antibodies  Estrogen Metabolism Pathway Diagram
 Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies  Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
 Glycosphingolipid Metabolism Pathway antibodies  Glycosphingolipid Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 The Activation Of Arylsulfatases Pathway antibodies  The Activation Of Arylsulfatases Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with ARSD and Nervous System Diseases
 Neurobehavioral Manifestations Antibodies  >7 publications with ARSD and Neurobehavioral Manifestations
 Immune System Diseases Antibodies  >2 publications with ARSD and Immune System Diseases
 Abnormalities, Multiple Antibodies  >2 publications with ARSD and Abnormalities, Multiple
 Inflammation Antibodies  >2 publications with ARSD and Inflammation
 Fibrosis Antibodies  >1 publications with ARSD and Fibrosis
 Fatty Liver Antibodies  >1 publications with ARSD and Fatty Liver
 Congenital Abnormalities Antibodies  >1 publications with ARSD and Congenital Abnormalities
Organs/Tissues associated with anti-ARSD antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >5 publications with ARSD and Bone
 Brain Antibodies  >2 publications with ARSD and Brain
 Kidney Antibodies  >2 publications with ARSD and Kidney
 Muscle Antibodies  >1 publications with ARSD and Muscle
 Liver Antibodies  >1 publications with ARSD and Liver
 Skin Antibodies  >1 publications with ARSD and Skin
 Testis Antibodies  >1 publications with ARSD and Testis
 Lung Antibodies  >1 publications with ARSD and Lung
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