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anti-NPR2 antibody :: Rabbit anti-Human Atrial Natriuretic Peptide, beta Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS641235 anti-NPR2 antibody
Unit / Price
0.05 mL  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Atrial Natriuretic Peptide, beta (NPR2), Polyclonal Antibody

 Also Known As   

Atrial Natriuretic Peptide, beta (ANP, Atrial Natriuretic Factor, ANF, ATFB6, CDD-ANF, Natriuretic Peptide A, NPPA, Prepronatriodilatin, PND)

 Product Synonym Names    Anti -Atrial Natriuretic Peptide, beta (ANP, Atrial Natriuretic Factor, ANF, ATFB6, CDD-ANF, Natriuretic Peptide A, NPPA, Prepronatriodilatin, PND)
 Product Gene Name   

anti-NPR2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 8; AC_000165.1 (60368097..60379016, complement). Location: chromosome: 8
 3D Structure    ModBase 3D Structure for P46197
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human beta-ANP.
 Purity/Purification    Serum
Serum
 Form/Format    Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
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 Immunogen    Synthetic peptide corresponding to human beta-ANP.
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 Preparation and Storage    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-NPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-NPR2 antibody    Antibodies; Abs to Cardiac Markers
 Applications Tested/Suitable for anti-NPR2 antibody   

Immunohistochemistry (IHC)

 Application Notes for anti-NPR2 antibody    Suitable for use in Immunohistochemistry and Immunofluorescence.
Dilution: Immunofluorescence: 1:200
Immunohistochemistry (PAP or ABC): 1:500
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NCBI/Uniprot data below describe general gene information for NPR2. It may not necessarily be applicable to this product.
 NCBI GI #    27806517
 NCBI GeneID    281357
 NCBI Accession #    NP_776551.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_174126.2 [Other Products]
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 UniProt Primary Accession #    P46197 [Other Products]
 UniProt Related Accession #    P46197 [Other Products]
 Molecular Weight    117,146 Da [Similar Products]
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 NCBI Official Full Name    atrial natriuretic peptide receptor 2
 NCBI Official Synonym Full Names    natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
 NCBI Official Symbol    NPR2 [Similar Products]
 NCBI Protein Information    atrial natriuretic peptide receptor 2; GC-B; ANP-B; ANPRB; NPR-B; ANPR-B; guanylate cyclase B; atrionatriuretic peptide receptor B; atrial natriuretic peptide receptor B; atrial natriuretic peptide B-type receptor; atrial natriuretic peptide receptor type B
 UniProt Protein Name    Atrial natriuretic peptide receptor 2
 UniProt Synonym Protein Names   
Atrial natriuretic peptide receptor type B; ANP-B; ANPR-B; NPR-B; Guanylate cyclase B
 Protein Family    Atrial natriuretic peptide receptor
 UniProt Gene Name    NPR2 [Similar Products]
 UniProt Synonym Gene Names    ANP-B; ANPR-B; NPR-B; GC-B [Similar Products]
 UniProt Entry Name    ANPRB_BOVIN
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 UniProt Comments for NPR2    Function: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth

By similarity.

Catalytic activity: GTP = 3',5'-cyclic GMP + diphosphate.

Subcellular location: Membrane; Single-pass type I membrane protein.

Post-translational modification: Phosphorylation of the protein kinase-like domain is required for full activation by CNP

By similarity.

Sequence similarities: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.Contains 1 guanylate cyclase domain.Contains 1 protein kinase domain.
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 Research Articles on NPR2    1. These data support the existence of a novel transducing cascade, involving Galpha(q16)beta gamma coupling M(3)AChR to NPR-GC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NPR2 antibodyPathways associated with anti-NPR2 antibody
 Reference Product  PubMed Publications
 NPPC antibody  >15 publications with NPR2 and NPPC
 PDE3A antibody  >1 publications with NPR2 and PDE3A
 Products by Pathway  Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Vascular Smooth Muscle Contraction Pathway antibodies  Vascular Smooth Muscle Contraction Pathway Diagram
 Vascular Smooth Muscle Contraction Pathway antibodies  Vascular Smooth Muscle Contraction Pathway Diagram
Diseases associated with anti-NPR2 antibodyOrgans/Tissues associated with anti-NPR2 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >6 publications with NPR2 and Cardiovascular Diseases
 Hypertension Antibodies  >2 publications with NPR2 and Hypertension
 Abnormalities, Multiple Antibodies  >2 publications with NPR2 and Abnormalities, Multiple
 Carcinoma Antibodies  >2 publications with NPR2 and Carcinoma
 Acromesomelic dysplasia, Maroteaux type Antibodies  >2 publications with NPR2 and Acromesomelic dysplasia, Maroteaux type
 Heart Defects, Congenital Antibodies  >1 publications with NPR2 and Heart Defects, Congenital
 Cardiomegaly Antibodies  >1 publications with NPR2 and Cardiomegaly
 Edema Antibodies  >1 publications with NPR2 and Edema
 Weight Gain Antibodies  >1 publications with NPR2 and Weight Gain
 Kidney Diseases Antibodies  >1 publications with NPR2 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with NPR2 and Brain
 Ovary Antibodies  >8 publications with NPR2 and Ovary
 Muscle Antibodies  >5 publications with NPR2 and Muscle
 Cartilage Antibodies  >4 publications with NPR2 and Cartilage
 Kidney Antibodies  >2 publications with NPR2 and Kidney
 Skin Antibodies  >1 publications with NPR2 and Skin
 Intestine Antibodies  >1 publications with NPR2 and Intestine
 Uterus Antibodies  >1 publications with NPR2 and Uterus
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