NP_001287736.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 29 kDa Predicted: 30 kDa
NCBI Official Full Name
basic leucine zipper transcriptional factor ATF-like 2 isoform 2
NCBI Official Synonym Full Names
basic leucine zipper ATF-like transcription factor 2
NCBI Official Synonym Symbols
NCBI Protein Information
basic leucine zipper transcriptional factor ATF-like 2
UniProt Protein Name
Basic leucine zipper transcriptional factor ATF-like 2
UniProt Synonym Protein Names
Suppressor of AP-1 regulated by IFN; SARI
UniProt Synonym Gene Names
UniProt Comments for BATF2
AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Research Articles on BATF2
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Products associated with anti-BATF2 antibody
Diseases associated with anti-BATF2 antibody
Organs/Tissues associated with anti-BATF2 antibody
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