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anti-BATF3 antibody :: Rabbit anti-Human BATF3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS153454
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BATF3, Polyclonal Antibody

★Popular Item★
 Also Known As   

BATF3 Antibody

 Product Synonym Names    Basic leucine zipper transcriptional factor ATF-like 3; SNFT; JDP1; JUNDM1; basic leucine zipper transcription factor, ATF-like 3
 Product Gene Name   

anti-BATF3 antibody

[Similar Products]
 Antibody/Peptide Pairs    BATF3 peptide (MBS153953) is used for blocking the activity of BATF3 antibody (MBS153454)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612470
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    BATF3 antibody is human, mouse and rat reactive. BATF3 antibody is predicted to have no cross-reactivity to other BATF family members.
 Purity/Purification    BATF3 antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    BATF3 antibody was raised against a 16 amino acid peptide near the amino terminus of human BATF3.
 Buffer    BATF3 antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    BATF3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
 Other Notes    Small volumes of anti-BATF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BATF3 antibody

   BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun (1) and can repress the transcription of IL-2 and MMP-1 (1,2). BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells (3,4).
 Applications Tested/Suitable for anti-BATF3 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-BATF3 antibody    BATF3 body can be used for detection of BATF3 by Western blot at 1 - 2 ug/ml.

Optimal dilutions for each application to be determined by the researcher.
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 Western Blot (WB) of anti-BATF3 antibody    Western blot analysis of BATF3 in 293 cell lysate with BATF3 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
anti-BATF3 antibody Western Blot (WB) (WB) image
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  of anti-BATF3 antibody    anti-BATF3 antibody  image
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NCBI/Uniprot data below describe general gene information for BATF3. It may not necessarily be applicable to this product.
 NCBI GI #    8924246
 NCBI GeneID    55509
 NCBI Accession #    NP_061134 [Other Products]
 NCBI GenBank Nucleotide #    NM_018664.2 [Other Products]
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 UniProt Related Accession #    Q9NR55 [Other Products]
 Molecular Weight    Predicted: 14 kDa

Observed: 17 kDa
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 NCBI Official Full Name    basic leucine zipper transcriptional factor ATF-like 3
 NCBI Official Synonym Full Names    basic leucine zipper transcription factor, ATF-like 3
 NCBI Official Symbol    BATF3 [Similar Products]
 NCBI Official Synonym Symbols   
JDP1; SNFT; JUNDM1
[Similar Products]
 NCBI Protein Information    basic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; Jun dimerization protein 1; Jun dimerization protein p21SNFT; 21-kD small nuclear factor isolated from T cells; 21 kDa small nuclear factor isolated from T-cells
 UniProt Protein Name    Basic leucine zipper transcriptional factor ATF-like 3
 UniProt Synonym Protein Names   
21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT
 Protein Family    Basic leucine zipper transcriptional factor
 UniProt Gene Name    BATF3 [Similar Products]
 UniProt Synonym Gene Names    SNFT; B-ATF-3 [Similar Products]
 UniProt Entry Name    BATF3_HUMAN
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 NCBI Summary for BATF3    This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
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 UniProt Comments for BATF3    BATF3: Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12- O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities. Belongs to the bZIP family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q32.3

Cellular Component: nucleus

Molecular Function: transcription corepressor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; response to virus; myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter
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 Research Articles on BATF3    1. overexpression of p21SNFT in HepG2 cells leads to repression of matrix metalloproteinase-1 by 70-80%
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BATF3 antibodyPathways associated with anti-BATF3 antibody
 Reference Product  PubMed Publications
 JUN antibody  >9 publications with BATF3 and JUN
 FOS antibody  >2 publications with BATF3 and FOS
 Products by Pathway  Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
Diseases associated with anti-BATF3 antibodyOrgans/Tissues associated with anti-BATF3 antibody
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >6 publications with BATF3 and Disease Models, Animal
 Inflammation Antibodies  >6 publications with BATF3 and Inflammation
 Nervous System Diseases Antibodies  >4 publications with BATF3 and Nervous System Diseases
 Lung Diseases Antibodies  >2 publications with BATF3 and Lung Diseases
 Liver Diseases Antibodies  >2 publications with BATF3 and Liver Diseases
 Necrosis Antibodies  >2 publications with BATF3 and Necrosis
 Pregnancy Complications Antibodies  >1 publications with BATF3 and Pregnancy Complications
 Adenocarcinoma Antibodies  >1 publications with BATF3 and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >6 publications with BATF3 and Lung
 Thymus Antibodies  >2 publications with BATF3 and Thymus
 Pancreas Antibodies  >1 publications with BATF3 and Pancreas
 Brain Antibodies  >1 publications with BATF3 and Brain
 Connective Tissue Antibodies  >1 publications with BATF3 and Connective Tissue
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