Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow BBOX1 rightarrow Polyclonal BBOX1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Myeloperoxidase (MPO) Antibody
 • SLC35B4 Antibody
 • Protein trunk (trk) Recombinant Protein
 • apolipoprotein M (APOM) ELISA Kit
 • CD3z Antibody
 • Fentanyl Antigen
 • ARHGEF11 Antibody
 • Gzms-B ELISA Kit
 • Ectonucleotide Pyrophosphatase, Phosphodiesterase 1 (ENPP1) Antibody
 • Telomerase (TERT) Antibody
 • Extracellular calcium-sensing receptor (CASR) ELISA Kit
 • P 38 Mitogen-Activated Protein Kinase (P38MAPK) ELISA Kit
 • Miraculin Recombinant Protein
 • Dynorphin ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-BBOX1 antibody :: Rabbit anti-Human, Mouse BBOX1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS835147
Unit / Price
0.1 mL  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BBOX1, Polyclonal Antibody

 Also Known As   

BBOX1 antibody

 Product Synonym Names    Polyclonal BBOX1; Anti-BBOX1; BBOX 1; BBOX-1; BBOX1; BBH; gamma-butyrobetaine 2-oxoglutarate dioxygenase 1; gamma-BBH; gamma-butyrobetaine hydroxylase; G-BBH; BBOX
 Product Gene Name   

anti-BBOX1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    603312
 3D Structure    ModBase 3D Structure for O75936
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    BBOX1 antibody was purified by antigen-affinity chromatography
 Form/Format    Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
 Concentration    0.76 mg/ml (lot specific)
Section Bar
 Biological Significance    This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
 Immunogen    BBOX1 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 1 and 293 of BBOX1
Section Bar
 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-BBOX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-BBOX1 antibody

   Affinity purified Rabbit polyclonal BBOX1 antibody
 Product Categories/Family for anti-BBOX1 antibody    Proteases, Inhibitors, & Enzymes; Purified Polyclonal Antibodies
 Applications Tested/Suitable for anti-BBOX1 antibody   

Western Blot (WB)

 Application Notes for anti-BBOX1 antibody    WB: 1:500-1:3000
Section Bar
 Western Blot (WB) of anti-BBOX1 antibody    Western blot analysis of 50 ug of whole cell lysate (A: mouse liver) using a 10 % SDS PAGE gel and BBOX1 antibody at a dilution of 1:500
anti-BBOX1 antibody Western Blot (WB) (WB) image
Section Bar
 Western Blot (WB) of anti-BBOX1 antibody    Western blot analysis of 30 ug of whole cell lysate (A:MOLT4) using a 7.5 % SDS PAGE gel and BBOX1 antibody at a dilution of 1:500
anti-BBOX1 antibody Western Blot (WB) (WB) image
Section Bar
 Immunofluorescence (IF) of anti-BBOX1 antibody    Immunofluorescence analysis of methanol-fixed A431, using BBOX1 antibody at 1:500 dilution.
anti-BBOX1 antibody Immunofluorescence (IF) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for BBOX1. It may not necessarily be applicable to this product.
 NCBI GI #    48145741
 NCBI GeneID    8424
 NCBI Accession #    CAG33093.1 [Other Products]
Section Bar
 UniProt Primary Accession #    O75936 [Other Products]
 UniProt Secondary Accession #    Q6IBJ2; B2R8L7; D3DQZ1 [Other Products]
 UniProt Related Accession #    O75936 [Other Products]
 Molecular Weight    45 kDa
Table BarTOPTable Bar
 NCBI Official Full Name    BBOX1
 NCBI Official Synonym Full Names    butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
 NCBI Official Symbol    BBOX1 [Similar Products]
 NCBI Official Synonym Symbols   
BBH; BBOX; G-BBH; gamma-BBH
[Similar Products]
 NCBI Protein Information    gamma-butyrobetaine dioxygenase
 UniProt Protein Name    Gamma-butyrobetaine dioxygenase
 UniProt Synonym Protein Names   
Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase
 Protein Family    Gamma-butyrobetaine dioxygenase
 UniProt Gene Name    BBOX1 [Similar Products]
 UniProt Synonym Gene Names    BBH; BBOX; Gamma-BBH [Similar Products]
 UniProt Entry Name    BODG_HUMAN
Section Bar
 NCBI Summary for BBOX1    This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for BBOX1    BBOX1: Catalyzes the formation of L-carnitine from gamma- butyrobetaine. Belongs to the gamma-BBH/TMLD family.

Protein type: EC 1.14.11.1; Amino Acid Metabolism - lysine degradation; Oxidoreductase

Chromosomal Location of Human Ortholog: 11p14.2

Cellular Component: mitochondrion; cytosol

Molecular Function: gamma-butyrobetaine dioxygenase activity; zinc ion binding; iron ion binding

Biological Process: carnitine biosynthetic process
Table BarTOPTable Bar
 Research Articles on BBOX1    1. the three-dimensional structure of recombinant human GBBH at 2.0A resolution was solved.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-BBOX1 antibodyPathways associated with anti-BBOX1 antibody
 Reference Product  PubMed Publications
 ALDH9A1 antibody  >2 publications with BBOX1 and ALDH9A1
 Products by Pathway  Pathway Diagram
 Carnitine Synthesis Pathway antibodies  Carnitine Synthesis Pathway Diagram
 L-carnitine Biosynthesis Pathway antibodies  L-carnitine Biosynthesis Pathway Diagram
 L-carnitine Biosynthesis Pathway antibodies  L-carnitine Biosynthesis Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
Diseases associated with anti-BBOX1 antibodyOrgans/Tissues associated with anti-BBOX1 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >4 publications with BBOX1 and Fatty Liver
 Muscular Diseases Antibodies  >1 publications with BBOX1 and Muscular Diseases
 Nervous System Diseases Antibodies  >1 publications with BBOX1 and Nervous System Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with BBOX1 and Neurobehavioral Manifestations
 Lung Diseases Antibodies  >1 publications with BBOX1 and Lung Diseases
 Inflammation Antibodies  >1 publications with BBOX1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with BBOX1 and Liver
 Kidney Antibodies  >2 publications with BBOX1 and Kidney
 Lung Antibodies  >1 publications with BBOX1 and Lung
 Ear Antibodies  >1 publications with BBOX1 and Ear
 Brain Antibodies  >1 publications with BBOX1 and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions