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anti-BCAP31 antibody :: Goat BCAP31/BAP31 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420668
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BCAP31/BAP31, Polyclonal Antibody

 Also Known As   

Goat anti-BCAP31/BAP31 Antibody

 Product Synonym Names    BCAP31; BAP31; DXS1357E; accessory protein BAP31; CDM; 6C6-AG; B-cell receptor-associated protein 31; CDM; 6C6 antigen; BCR-associated protein Bap31; OTTHUMP00000025978; p28 Bap31; BCAP31 antibody; BAP31 antibody; DXS1357E antibody; accessory protein BAP31 antibody; CDM antibody; 6C6-AG antibody; B-cell receptor-associated protein 31 antibody; CDM antibody; 6C6 antigen antibody; BCR-associated protein Bap31 antibody; OTTHUMP00000025978 antibody; p28 Bap31 antibody; BCAP31 / BAP31
 Product Gene Name   

anti-BCAP31 antibody

[Similar Products]
 Product Synonym Gene Name    BAP31 [Similar Products]
 Antibody/Peptide Pairs    BCAP31 / BAP31 peptide (MBS425294) is used for blocking the activity of BCAP31/BAP31 antibody (MBS420668)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    QAAVDGPMDK KEE
 OMIM    300398
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Dog, Pig, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-QAAVDGPMDKKEE, from the C Terminus of the protein sequence according to NP_001132929.1; NP_005736.3.
 Epitope    C Terminus
 Note    This antibody is expected to recognise isoform a (NP_001132929.1) and isoform b (NP_005736.3; NP_001132913.1).
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-BCAP31 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-BCAP31 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-BCAP31 antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 30kDa band observed in Human Placenta and Brain lysate (predicted MW of 28kDa according to NP_005736). Recommended for use at 1-3ug/ml.
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 Western Blot (WB) of anti-BCAP31 antibody    (0.1ug/ml) staining of Human Breast lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. chemiluminescence.
anti-BCAP31 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for BCAP31. It may not necessarily be applicable to this product.
 NCBI GI #    213511508
 NCBI GeneID    10134
 NCBI Accession #    NP_001132929.1 [Other Products]
 NCBI Related Accession #    NP_005736.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_001139457.2 [Other Products]
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 UniProt Secondary Accession #    Q13836; Q96CF0; B3KQ79; D3DWV5 [Other Products]
 UniProt Related Accession #    P51572 [Other Products]
 Molecular Weight    34,752 Da
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 NCBI Official Full Name    B-cell receptor-associated protein 31 isoform a
 NCBI Official Synonym Full Names    B-cell receptor-associated protein 31
 NCBI Official Symbol    BCAP31 [Similar Products]
 NCBI Official Synonym Symbols   
CDM; DDCH; BAP31; 6C6-AG; DXS1357E
[Similar Products]
 NCBI Protein Information    B-cell receptor-associated protein 31
 UniProt Protein Name    B-cell receptor-associated protein 31
 UniProt Synonym Protein Names   
6C6-AG tumor-associated antigen; Protein CDM; p28
 Protein Family    B-cell receptor-associated protein
 UniProt Gene Name    BCAP31 [Similar Products]
 UniProt Synonym Gene Names    BAP31; DXS1357E; BCR-associated protein 31; Bap31 [Similar Products]
 UniProt Entry Name    BAP31_HUMAN
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 NCBI Summary for BCAP31    This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]
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 UniProt Comments for BCAP31    BCAP31 iso2: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis. Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB. Ubiquitous. Belongs to the BCAP29/BCAP31 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; lipid particle; membrane; translocon complex

Molecular Function: protein binding

Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cell structure disassembly during apoptosis; elevation of cytosolic calcium ion concentration; elevation of mitochondrial calcium ion concentration; ER to Golgi vesicle-mediated transport; positive regulation of caspase activity; reduction of endoplasmic reticulum calcium ion concentration

Disease: Deafness, Dystonia, And Cerebral Hypomyelination
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 Research Articles on BCAP31    1. The C-terminal domain of BAP31 is exposed on the cell surface of human embryonic stem cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BCAP31 antibodyPathways associated with anti-BCAP31 antibody
 Reference Product  PubMed Publications
 CASP8 antibody  >24 publications with BCAP31 and CASP8
 BCL2 antibody  >1 publications with BCAP31 and BCL2
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Programmed Cell Death Pathway antibodies  Programmed Cell Death Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
Diseases associated with anti-BCAP31 antibodyOrgans/Tissues associated with anti-BCAP31 antibody
 Disease Name  Pubmed Publications
 Death Antibodies  >29 publications with BCAP31 and Death
 Nervous System Diseases Antibodies  >6 publications with BCAP31 and Nervous System Diseases
 Necrosis Antibodies  >5 publications with BCAP31 and Necrosis
 Liver Diseases Antibodies  >3 publications with BCAP31 and Liver Diseases
 Mental Disorders Antibodies  >2 publications with BCAP31 and Mental Disorders
 Carcinoma Antibodies  >2 publications with BCAP31 and Carcinoma
 Adenocarcinoma Antibodies  >2 publications with BCAP31 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >2 publications with BCAP31 and Cardiovascular Diseases
 Inflammation Antibodies  >2 publications with BCAP31 and Inflammation
 Lung Diseases Antibodies  >1 publications with BCAP31 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >12 publications with BCAP31 and Blood
 Brain Antibodies  >7 publications with BCAP31 and Brain
 Liver Antibodies  >6 publications with BCAP31 and Liver
 Testis Antibodies  >4 publications with BCAP31 and Testis
 Muscle Antibodies  >4 publications with BCAP31 and Muscle
 Nerve Antibodies  >4 publications with BCAP31 and Nerve
 Kidney Antibodies  >3 publications with BCAP31 and Kidney
 Lung Antibodies  >3 publications with BCAP31 and Lung
 Thymus Antibodies  >3 publications with BCAP31 and Thymus
 Spleen Antibodies  >2 publications with BCAP31 and Spleen
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