NP_001070908.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 106 kD Predicted: 107 kDa
NCBI Official Full Name
bcl-2-associated transcription factor 1 isoform 2
NCBI Official Synonym Full Names
BCL2 associated transcription factor 1
NCBI Protein Information
bcl-2-associated transcription factor 1
UniProt Protein Name
Bcl-2-associated transcription factor 1
UniProt Synonym Protein Names
BCLAF1 and THRAP3 family member 1
UniProt Synonym Gene Names
NCBI Summary for BCLAF1
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for BCLAF1
Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Research Articles on BCLAF1
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Products associated with anti-BCLAF1 antibody
Diseases associated with anti-BCLAF1 antibody
Organs/Tissues associated with anti-BCLAF1 antibody
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