View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-BMP-2 antibody :: Rabbit BMP-2 Polyclonal Antibody Catalog # MBS220690 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name BMP-2, Polyclonal Antibody Full Product Name RABBIT ANTI HUMAN BMP-2 Product Gene Name anti-BMP-2 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Immunogen Sequence Q-A-K-H-K- Q-R-K-R-L- K-S-S-C OMIM 112261 3D Structure ModBase 3D Structure for P12643 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Vertebrates (Expected from Sequence) Specificity This item recognizes human bone morphogenetic protein 2 (BMP-2), a secreted peptide that induces cartilage and bone formation. Form/Format PurifiedPurified IgG - liquid Concentration IgG concentration 5.0 mg/ml (lot specific) Perservative Stabilisers 0.09% Sodium Azide (NaN3)Preparation Immunogen Synthetic peptide corresponding to the amino acids 1 - 14 of human BMP-2 conjugated to Keyhole limpet Haemocyanin.Buffer Solution Target Species Human Preparation and Storage Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.Shelf Life: 18 months from date of despatch. Other Notes Small volumes of anti-BMP-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-BMP-2 antibody MBS220690 recognizes human bone morphogenetic protein 2 (BMP-2), a secreted peptide that induces cartilage and bone formation. Applications Tested/Suitable for anti-BMP-2 antibody ELISA (EIA) TOP NCBI/Uniprot data below describe general gene information for BMP-2. It may not necessarily be applicable to this product. NCBI GI # 4557369 NCBI GeneID 650 NCBI Accession # NP_001191.1 [Other Products] NCBI GenBank Nucleotide # NM_001200.2 [Other Products] UniProt Primary Accession # P12643 [Other Products] UniProt Related Accession # P12643[Other Products] Molecular Weight 44,702 Da TOP NCBI Official Full Name bone morphogenetic protein 2 preproprotein NCBI Official Synonym Full Names bone morphogenetic protein 2 NCBI Official Symbol BMP2 [Similar Products] NCBI Official Synonym Symbols BDA2; BMP2A [Similar Products] NCBI Protein Information bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A UniProt Protein Name Bone morphogenetic protein 2 UniProt Synonym Protein Names Bone morphogenetic protein 2A; BMP-2A Protein Family BMP-2-inducible protein kinase UniProt Gene Name BMP2 [Similar Products] UniProt Synonym Gene Names BMP2A; BMP-2; BMP-2A [Similar Products] UniProt Entry Name BMP2_HUMAN TOP NCBI Summary for BMP-2 The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008] TOP UniProt Comments for BMP-2 Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). Research Articles on BMP-2 1. Coleusin factor represents a new type of BMP-2 inducer that restores differentiation in osteosarcoma cells. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-BMP-2 antibody Reference Product PubMed Publications BMPR2 antibody >207 publications with BMP-2 and BMPR2 BMPR1A antibody >180 publications with BMP-2 and BMPR1A SMAD4 antibody >96 publications with BMP-2 and SMAD4 BMPR1B antibody >60 publications with BMP-2 and BMPR1B SMAD7 antibody >34 publications with BMP-2 and SMAD7 NOG antibody >11 publications with BMP-2 and NOG ACVR2B antibody >9 publications with BMP-2 and ACVR2B GREM2 antibody >8 publications with BMP-2 and GREM2 CHRD antibody >3 publications with BMP-2 and CHRD SOSTDC1 antibody >2 publications with BMP-2 and SOSTDC1 Pathways associated with anti-BMP-2 antibody Products by Pathway Pathway Diagram Adipogenesis Pathway antibodies Adipogenesis Pathway Diagram BDNF Signaling Pathway antibodies BDNF Signaling Pathway Diagram BMP Signaling Pathway antibodies BMP Signaling Pathway Diagram BMP Signaling Pathway antibodies BMP Signaling Pathway Diagram BMP Signalling And Regulation Pathway antibodies BMP Signalling And Regulation Pathway Diagram Basal Cell Carcinoma Pathway antibodies Basal Cell Carcinoma Pathway Diagram Basal Cell Carcinoma Pathway antibodies Basal Cell Carcinoma Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Elastic Fibre Formation Pathway antibodies Elastic Fibre Formation Pathway Diagram Diseases associated with anti-BMP-2 antibody Disease Name Pubmed Publications Bone Diseases Antibodies >571 publications with BMP-2 and Bone Diseases Necrosis Antibodies >113 publications with BMP-2 and Necrosis Inflammation Antibodies >93 publications with BMP-2 and Inflammation Pain Antibodies >46 publications with BMP-2 and Pain Hypertrophy Antibodies >45 publications with BMP-2 and Hypertrophy Hypertension Antibodies >44 publications with BMP-2 and Hypertension Fibrosis Antibodies >34 publications with BMP-2 and Fibrosis Breast Neoplasms Antibodies >33 publications with BMP-2 and Breast Neoplasms Adenocarcinoma Antibodies >32 publications with BMP-2 and Adenocarcinoma Kidney Diseases Antibodies >32 publications with BMP-2 and Kidney Diseases Organs/Tissues associated with anti-BMP-2 antibody Organ/Tissue Name Pubmed Publications Bone Antibodies >4204 publications with BMP-2 and Bone Connective Tissue Antibodies >649 publications with BMP-2 and Connective Tissue Embryonic Tissue Antibodies >456 publications with BMP-2 and Embryonic Tissue Heart Antibodies >192 publications with BMP-2 and Heart Brain Antibodies >163 publications with BMP-2 and Brain Kidney Antibodies >95 publications with BMP-2 and Kidney Lung Antibodies >83 publications with BMP-2 and Lung Liver Antibodies >70 publications with BMP-2 and Liver Eye Antibodies >63 publications with BMP-2 and Eye Uterus Antibodies >30 publications with BMP-2 and Uterus TOP © 2006-24 MyBioSource.com. All rights reserved. Privacy Policy | Terms & Conditions Our Best Sellers Transforming Growth Factor Beta (TGF-beta) ELISA Kit ELMO1 cDNA Clone ISY1 Antibody 14-3-3 sigma-Stratifin (SFN) Antibody complement component 4 binding protein, beta (C4BPB) ELISA Kit Atrial Natriuretic Peptide (ANP) ELISA Kit ARHGDIB Antibody Procalcitonin (PCT) ELISA Kit ELISA Antibodies Secondary Antibodies Antigens Biochemicals cDNA Clones Kits Peptides Rec Proteins Protein Family Request a Quote Please fill out the form below and our representative will get back to you shortly. Catalog # MBS000000 Your E-mail (required) Ship to Country (required) United StatesAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegowinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCote DIvoireCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrance MetropolitanFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuineaGuinea-bissauGuyanaHaitiHeard and Mc Donald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKorea Democratic People Republic ofKorea Republic ofKuwaitKyrgyzstanLao People Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacauMacedonia The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia Federated States ofMoldova Republic ofMonacoMongoliaMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSeychellesSierra LeoneSingaporeSlovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSpainSri LankaSt. HelenaSt. Pierre and MiquelonSudanSurinameSvalbard and Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania United Republic ofThailandTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUnited States Minor Outlying IslandsUruguayUzbekistanVanuatuVatican City State (Holy See)VenezuelaViet NamVirgin Islands (British)Virgin Islands (U.S.)Wallis and Futuna IslandsWestern SaharaYemenYugoslaviaZaireZambiaZimbabwe Postal/Zip Code (required) Your Name Your Telephone Your Inquiries, Comments or Full Shipping Address (required) Contact Us Please fill out the form below and our representative will get back to you shortly. Inquiry for # MBS000000 Your Name Your Telephone Your E-mail (required) Your Inquiries or Comments