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anti-BAMBI antibody :: BMP and activin membrane-bound inhibitor homolog Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS719289 anti-BAMBI antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP and activin membrane-bound inhibitor homolog (BAMBI), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) polyclonal Antibody

 Product Gene Name   

anti-BAMBI antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604444
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 Clonality    Polyclonal
 Isotype    IgG
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human BAMBI
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-BAMBI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-BAMBI antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for BAMBI. It may not necessarily be applicable to this product.
 NCBI GI #    6912534
 NCBI GeneID    25805
 NCBI Accession #    NP_036474.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012342.2 [Other Products]
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 UniProt Related Accession #    Q13145 [Other Products]
 Molecular Weight    29,108 Da [Similar Products]
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 NCBI Official Full Name    BMP and activin membrane-bound inhibitor homolog
 NCBI Official Synonym Full Names    BMP and activin membrane-bound inhibitor
 NCBI Official Symbol    BAMBI [Similar Products]
 NCBI Official Synonym Symbols   
NMA
[Similar Products]
 NCBI Protein Information    BMP and activin membrane-bound inhibitor homolog; non-metastatic gene A protein; putative transmembrane protein NMA
 UniProt Protein Name    BMP and activin membrane-bound inhibitor homolog
 UniProt Synonym Protein Names   
Non-metastatic gene A protein; Putative transmembrane protein NMA
 Protein Family    BMP and activin membrane-bound inhibitor
 UniProt Gene Name    BAMBI [Similar Products]
 UniProt Synonym Gene Names    NMA [Similar Products]
 UniProt Entry Name    BAMBI_HUMAN
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 NCBI Summary for BAMBI    This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BAMBI    BAMBI: Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.

Protein type: Membrane protein, integral; Inhibitor

Chromosomal Location of Human Ortholog: 10p12.3-p11.2

Cellular Component: cytoplasm; integral to membrane; plasma membrane

Molecular Function: frizzled binding; punt binding

Biological Process: regulation of cell shape; cell migration; positive regulation of protein binding; transforming growth factor beta receptor signaling pathway; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway
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 Research Articles on BAMBI    1. BAMBI alone or in combination with Smad7 was significantly associated with the OS and DFS. These findings suggest that BAMBI and Smad7 may cooperatively inhibit the TGF-beta signaling, and thus promote the progression of gastric cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BAMBI antibodyPathways associated with anti-BAMBI antibody
 Reference Product  PubMed Publications
 BMP4 antibody  >14 publications with BAMBI and BMP4
 BMP2 antibody  >9 publications with BAMBI and BMP2
 BMP7 antibody  >7 publications with BAMBI and BMP7
 BMPR2 antibody  >6 publications with BAMBI and BMPR2
 BMPR1A antibody  >2 publications with BAMBI and BMPR1A
 CHRD antibody  >1 publications with BAMBI and CHRD
 Products by Pathway  Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downregulation Of TGF-beta Receptor Signaling Pathway antibodies  Downregulation Of TGF-beta Receptor Signaling Pathway Diagram
 Loss Of Function Of SMAD2/3 In Cancer Pathway antibodies  Loss Of Function Of SMAD2/3 In Cancer Pathway Diagram
 Loss Of Function Of SMAD4 In Cancer Pathway antibodies  Loss Of Function Of SMAD4 In Cancer Pathway Diagram
 Loss Of Function Of TGFBR1 In Cancer Pathway antibodies  Loss Of Function Of TGFBR1 In Cancer Pathway Diagram
 Loss Of Function Of TGFBR2 In Cancer Pathway antibodies  Loss Of Function Of TGFBR2 In Cancer Pathway Diagram
 SMAD2/3 MH2 Domain Mutants In Cancer Pathway antibodies  SMAD2/3 MH2 Domain Mutants In Cancer Pathway Diagram
 SMAD2/3 Phosphorylation Motif Mutants In Cancer Pathway antibodies  SMAD2/3 Phosphorylation Motif Mutants In Cancer Pathway Diagram
 SMAD4 MH2 Domain Mutants In Cancer Pathway antibodies  SMAD4 MH2 Domain Mutants In Cancer Pathway Diagram
Diseases associated with anti-BAMBI antibodyOrgans/Tissues associated with anti-BAMBI antibody
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >20 publications with BAMBI and Fibrosis
 Liver Diseases Antibodies  >15 publications with BAMBI and Liver Diseases
 Carcinoma Antibodies  >15 publications with BAMBI and Carcinoma
 Inflammation Antibodies  >12 publications with BAMBI and Inflammation
 Adenocarcinoma Antibodies  >10 publications with BAMBI and Adenocarcinoma
 Disease Models, Animal Antibodies  >9 publications with BAMBI and Disease Models, Animal
 Nervous System Diseases Antibodies  >9 publications with BAMBI and Nervous System Diseases
 Pain Antibodies  >6 publications with BAMBI and Pain
 Neoplasm Metastasis Antibodies  >6 publications with BAMBI and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >6 publications with BAMBI and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >63 publications with BAMBI and Bone
 Liver Antibodies  >21 publications with BAMBI and Liver
 Vascular Antibodies  >16 publications with BAMBI and Vascular
 Embryonic Tissue Antibodies  >13 publications with BAMBI and Embryonic Tissue
 Brain Antibodies  >8 publications with BAMBI and Brain
 Connective Tissue Antibodies  >7 publications with BAMBI and Connective Tissue
 Kidney Antibodies  >7 publications with BAMBI and Kidney
 Eye Antibodies  >7 publications with BAMBI and Eye
 Heart Antibodies  >7 publications with BAMBI and Heart
 Lung Antibodies  >6 publications with BAMBI and Lung
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