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anti-BMP2 antibody :: Rabbit anti-Human BMP2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS241002
Immunohistochemistry (IHC)
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP2, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit Polyclonal to Human BMP2

 Product Synonym Names    Anti-BMP2 Antibody (aa86-102) IHC-plus; BMP2; BDA2; BMP-2; BMP-2A; BMP2A; Bone morphogenetic protein 2; Bone morphogenetic protein 2A; Human BMP2
 Product Gene Name   

anti-BMP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    112261
 3D Structure    ModBase 3D Structure for P12643
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Amino acids 86 to 102 of human BMP2
 Purity/Purification    Protein G Purified
 Form/Format    PBS, 0.09% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human BMP2.
 Immunogen Type    Synthetic peptide
 Immunogen    BMP2 antibody was raised against synthetic peptide from human BMP2.
 Antigen Modification    aa86-102
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 Preparation and Storage    Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
 Other Notes    Small volumes of anti-BMP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BMP2 antibody

   BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein induces bone formation. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva.
 Product Categories/Family for anti-BMP2 antibody    Family: TGF beta
 Applications Tested/Suitable for anti-BMP2 antibody   

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

 Application Notes for anti-BMP2 antibody    ELISA (1:000 - 1:1000), IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
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 Immunohistochemistry (IHC) of anti-BMP2 antibody    Anti-BMP2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-BMP2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for BMP2. It may not necessarily be applicable to this product.
 NCBI GI #    4557369
 NCBI GeneID    650
 NCBI Accession #    NP_001191.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001200.2 [Other Products]
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 UniProt Primary Accession #    P12643 [Other Products]
 UniProt Related Accession #    P12643 [Other Products]
 Molecular Weight    44,702 Da
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 NCBI Official Full Name    bone morphogenetic protein 2 preproprotein
 NCBI Official Synonym Full Names    bone morphogenetic protein 2
 NCBI Official Symbol    BMP2 [Similar Products]
 NCBI Official Synonym Symbols   
BDA2; BMP2A
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A
 UniProt Protein Name    Bone morphogenetic protein 2
 UniProt Synonym Protein Names   
Bone morphogenetic protein 2A; BMP-2A
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP2 [Similar Products]
 UniProt Synonym Gene Names    BMP2A; BMP-2; BMP-2A [Similar Products]
 UniProt Entry Name    BMP2_HUMAN
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 NCBI Summary for BMP2    The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP2    Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
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 Research Articles on BMP2    1. BMP-2 silencing can significantly inhibit non-small lung cancer cell proliferation and migration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BMP2 antibodyPathways associated with anti-BMP2 antibody
 Reference Product  PubMed Publications
 BMPR2 antibody  >206 publications with BMP2 and BMPR2
 BMPR1A antibody  >179 publications with BMP2 and BMPR1A
 SMAD4 antibody  >95 publications with BMP2 and SMAD4
 BMPR1B antibody  >58 publications with BMP2 and BMPR1B
 SMAD7 antibody  >33 publications with BMP2 and SMAD7
 NOG antibody  >11 publications with BMP2 and NOG
 ACVR2B antibody  >9 publications with BMP2 and ACVR2B
 GREM2 antibody  >8 publications with BMP2 and GREM2
 CHRD antibody  >3 publications with BMP2 and CHRD
 SOSTDC1 antibody  >2 publications with BMP2 and SOSTDC1
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signalling And Regulation Pathway antibodies  BMP Signalling And Regulation Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
Diseases associated with anti-BMP2 antibodyOrgans/Tissues associated with anti-BMP2 antibody
 Disease Name  Pubmed Publications
 Bone Diseases Antibodies  >564 publications with BMP2 and Bone Diseases
 Necrosis Antibodies  >111 publications with BMP2 and Necrosis
 Inflammation Antibodies  >93 publications with BMP2 and Inflammation
 Pain Antibodies  >46 publications with BMP2 and Pain
 Hypertrophy Antibodies  >45 publications with BMP2 and Hypertrophy
 Hypertension Antibodies  >44 publications with BMP2 and Hypertension
 Fibrosis Antibodies  >34 publications with BMP2 and Fibrosis
 Breast Neoplasms Antibodies  >32 publications with BMP2 and Breast Neoplasms
 Kidney Diseases Antibodies  >31 publications with BMP2 and Kidney Diseases
 Lung Neoplasms Antibodies  >21 publications with BMP2 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4167 publications with BMP2 and Bone
 Connective Tissue Antibodies  >645 publications with BMP2 and Connective Tissue
 Embryonic Tissue Antibodies  >454 publications with BMP2 and Embryonic Tissue
 Heart Antibodies  >192 publications with BMP2 and Heart
 Brain Antibodies  >161 publications with BMP2 and Brain
 Kidney Antibodies  >94 publications with BMP2 and Kidney
 Lung Antibodies  >82 publications with BMP2 and Lung
 Liver Antibodies  >70 publications with BMP2 and Liver
 Eye Antibodies  >63 publications with BMP2 and Eye
 Uterus Antibodies  >29 publications with BMP2 and Uterus
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