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anti-BMP2 antibody :: Rabbit anti-Human BMP2 BMP2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS534101 anti-BMP2 antibody
Unit / Price
0.1 mg  /  $535 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP2, Polyclonal Antibody

 Also Known As   

BMP2 antibody

 Product Synonym Names    Polyclonal BMP2; Anti-BMP2; BMP-2; BMP 2; BMP2; Bone Morphogenetic; BMP-2A; 2
 Product Gene Name   

anti-BMP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P49001
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human BMP2
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 Form/Format    Lyophilized from PBS, pH 7.2. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/ml.
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 Biological Significance    BMPs (Bone Morphogenetic Proteins) belong to the TGF beta superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond.
 Immunogen    BMP2 antibody was raised in rabbit using highly pure human recombinant human BMP-2 as the immunogen.
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 Preparation and Storage    Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-BMP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BMP2 antibody

   Affinity purified Rabbit polyclonal BMP2 antibody
 Product Categories/Family for anti-BMP2 antibody    Differentiation & Development ; Purified Polyclonal Antibodies
 Applications Tested/Suitable for anti-BMP2 antibody   

ELISA (EIA), Inhibition, Western Blot (WB)

 Application Notes for anti-BMP2 antibody    ELISA: 0.5-2 ug/ml
Inhibition: 1.3-1.9 ug/ml
WB: 0.1-0.2 ug/ml
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NCBI/Uniprot data below describe general gene information for BMP2. It may not necessarily be applicable to this product.
 NCBI GI #    8392990
 NCBI GeneID    29373
 NCBI Accession #    NP_058874 [Other Products]
 NCBI GenBank Nucleotide #    NM_017178.1 [Other Products]
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 UniProt Primary Accession #    P49001 [Other Products]
 UniProt Related Accession #    P49001 [Other Products]
 Molecular Weight    26 kDa (predicted detection band MW)
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 NCBI Official Full Name    bone morphogenetic protein 2
 NCBI Official Synonym Full Names    bone morphogenetic protein 2
 NCBI Official Symbol    Bmp2 [Similar Products]
 NCBI Protein Information    bone morphogenetic protein 2
 UniProt Protein Name    Bone morphogenetic protein 2
 UniProt Synonym Protein Names   
Bone morphogenetic protein 2A; BMP-2A
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    Bmp2 [Similar Products]
 UniProt Synonym Gene Names    Bmp-2; BMP-2; BMP-2A [Similar Products]
 UniProt Entry Name    BMP2_RAT
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 NCBI Summary for BMP2    involved in cellular signaling during limb development; induces bone formation [RGD, Feb 2006]
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 UniProt Comments for BMP2    BMP2: Induces cartilage and bone formation. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Cellular Component: extracellular space; protein complex; cell surface; cytoplasm; extracellular region

Molecular Function: protein domain specific binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity; phosphatase activator activity; cytokine activity; SMAD binding; transforming growth factor beta receptor binding; retinol dehydrogenase activity; receptor binding

Biological Process: activation of MAPK activity; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; heart development; adrenocorticotropin hormone secreting cell differentiation; telencephalon regionalization; protein amino acid phosphorylation; cardiac muscle cell differentiation; BMP signaling pathway; regulation of apoptosis; ovulation cycle; chondrocyte differentiation; inner ear development; regulation of odontogenesis of dentine-containing teeth; positive regulation of astrocyte differentiation; pericardium development; positive regulation of neurogenesis; cell fate commitment; organ morphogenesis; mesenchymal cell differentiation; response to mechanical stimulus; regulation of MAPKKK cascade; positive regulation of osteoblast proliferation; positive regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of endothelial cell proliferation; positive regulation of cell differentiation; negative regulation of transcription, DNA-dependent; negative regulation of calcium-independent cell-cell adhesion; positive regulation of odontogenesis; proteoglycan metabolic process; embryonic heart tube anterior/posterior pattern formation; negative regulation of insulin-like growth factor receptor signaling pathway; thyroid stimulating hormone secreting cell differentiation; negative regulation of transcription from RNA polymerase II promoter; bone mineralization; negative regulation of cell cycle; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; positive regulation of MAPKKK cascade; negative regulation of aldosterone biosynthetic process; cardiac muscle morphogensis; inflammatory response; positive regulation of Wnt receptor signaling pathway; cardiac cell differentiation; ossification; Notch signaling pathway; response to retinoic acid; protein destabilization; in utero embryonic development; positive regulation of bone mineralization; positive regulation of ossification; odontogenesis of dentine-containing teeth; osteoblast differentiation; positive regulation of osteoblast differentiation; telencephalon development; ureteric bud branching; cartilage development; response to hypoxia; epithelial to mesenchymal transition; positive regulation of protein amino acid phosphorylation; positive regulation of neuron differentiation; positive regulation of cell migration; growth
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 Research Articles on BMP2    1. BMP2 is a potential regulator of nigrostriatal pathway development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BMP2 antibodyPathways associated with anti-BMP2 antibody
 Reference Product  PubMed Publications
 Smad1 antibody  >338 publications with BMP2 and Smad1
 Bmpr2 antibody  >214 publications with BMP2 and Bmpr2
 Smad5 antibody  >108 publications with BMP2 and Smad5
 Bmpr1a antibody  >92 publications with BMP2 and Bmpr1a
 Smad6 antibody  >60 publications with BMP2 and Smad6
 Smad7 antibody  >34 publications with BMP2 and Smad7
 Smad9 antibody  >13 publications with BMP2 and Smad9
 Nog antibody  >12 publications with BMP2 and Nog
 Acvr2b antibody  >9 publications with BMP2 and Acvr2b
 Chrd antibody  >3 publications with BMP2 and Chrd
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
Diseases associated with anti-BMP2 antibodyOrgans/Tissues associated with anti-BMP2 antibody
 Disease Name  Pubmed Publications
 Bone Diseases Antibodies  >591 publications with BMP2 and Bone Diseases
 Necrosis Antibodies  >120 publications with BMP2 and Necrosis
 Inflammation Antibodies  >103 publications with BMP2 and Inflammation
 Lung Diseases Antibodies  >52 publications with BMP2 and Lung Diseases
 Pain Antibodies  >49 publications with BMP2 and Pain
 Hypertension Antibodies  >47 publications with BMP2 and Hypertension
 Hypertrophy Antibodies  >46 publications with BMP2 and Hypertrophy
 Fibrosis Antibodies  >37 publications with BMP2 and Fibrosis
 Kidney Diseases Antibodies  >35 publications with BMP2 and Kidney Diseases
 Breast Neoplasms Antibodies  >34 publications with BMP2 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >64 publications with BMP2 and Eye
 Pancreas Antibodies  >13 publications with BMP2 and Pancreas
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