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anti-BMP5 antibody :: Rabbit anti-Human, Mouse BMP5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9601335
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP5, Polyclonal Antibody

★Popular Item★
 Also Known As   

BMP5 Antibody

 Product Synonym Names    BMP 5; BMP-5; Bmp5; BMP5_HUMAN; Bone morphogenetic protein 5; MGC34244
 Product Gene Name   

anti-BMP5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P22003
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    BMP5 antibody detects endogenous levels of total BMP5
 Purity/Purification    The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
 Form/Format    Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1mg/ml (lot specific)
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 Immunogen    A synthesized peptide derived from human BMP5
 Subcellular Location    Secreted.
 Tissue Specificity    Expressed in the lung and liver.
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-BMP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BMP5 antibody

   Function: Induces cartilage and bone formation.
Subunit Structure: Homodimer; disulfide-linked.
Similarity: Belongs to the TGF-beta family.
 Applications Tested/Suitable for anti-BMP5 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-BMP5 antibody    WB: 1:500-1:2000
IHC: 1:50-1:200
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 Immunohistochemistry (IHC) of anti-BMP5 antibody    MBS9601335 at 1/100 staining human liver tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-BMP5 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-BMP5 antibody    Western blot analysis of BMP5 expression in HUVEC cells, The lane on the left is treated with the antigen-specific peptide.
anti-BMP5 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for BMP5. It may not necessarily be applicable to this product.
 NCBI GI #    1047600467
 NCBI GeneID    653
 NCBI Accession #    NP_001316683.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001329754.1 [Other Products]
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 UniProt Primary Accession #    P22003 [Other Products]
 UniProt Secondary Accession #    Q9H547; Q9NTM5; B4E0Y4 [Other Products]
 UniProt Related Accession #    P22003 [Other Products]
 Molecular Weight    Observed: 51 kDa
Predicted: 52 kDa
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 NCBI Official Full Name    bone morphogenetic protein 5 isoform 2
 NCBI Official Synonym Full Names    bone morphogenetic protein 5
 NCBI Official Symbol    BMP5 [Similar Products]
 NCBI Protein Information    bone morphogenetic protein 5
 UniProt Protein Name    Bone morphogenetic protein 5
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP5 [Similar Products]
 UniProt Synonym Gene Names    BMP-5 [Similar Products]
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 NCBI Summary for BMP5    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016]
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 UniProt Comments for BMP5    Induces cartilage and bone formation.
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 Research Articles on BMP5    1. findings suggested that BMP5 might be a potential prognostic biomarker or therapeutic target for patients with NSCLC
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BMP5 antibodyPathways associated with anti-BMP5 antibody
 Reference Product  PubMed Publications
 BMP2 antibody  >51 publications with BMP5 and BMP2
 BMP4 antibody  >38 publications with BMP5 and BMP4
 BMPR1A antibody  >7 publications with BMP5 and BMPR1A
 BMPR2 antibody  >5 publications with BMP5 and BMPR2
 BMPR1B antibody  >4 publications with BMP5 and BMPR1B
 NKX2-5 antibody  >2 publications with BMP5 and NKX2-5
 SOST antibody  >1 publications with BMP5 and SOST
 NOG antibody  >1 publications with BMP5 and NOG
 Products by Pathway  Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
Diseases associated with anti-BMP5 antibodyOrgans/Tissues associated with anti-BMP5 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >7 publications with BMP5 and Inflammation
 Carcinoma Antibodies  >6 publications with BMP5 and Carcinoma
 Nervous System Diseases Antibodies  >5 publications with BMP5 and Nervous System Diseases
 Fibrosis Antibodies  >5 publications with BMP5 and Fibrosis
 Necrosis Antibodies  >3 publications with BMP5 and Necrosis
 Breast Neoplasms Antibodies  >2 publications with BMP5 and Breast Neoplasms
 Kidney Diseases Antibodies  >2 publications with BMP5 and Kidney Diseases
 Adenocarcinoma Antibodies  >2 publications with BMP5 and Adenocarcinoma
 Hypertrophy Antibodies  >2 publications with BMP5 and Hypertrophy
 Cell Transformation, Neoplastic Antibodies  >2 publications with BMP5 and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >24 publications with BMP5 and Embryonic Tissue
 Connective Tissue Antibodies  >17 publications with BMP5 and Connective Tissue
 Muscle Antibodies  >15 publications with BMP5 and Muscle
 Brain Antibodies  >9 publications with BMP5 and Brain
 Heart Antibodies  >8 publications with BMP5 and Heart
 Lung Antibodies  >6 publications with BMP5 and Lung
 Eye Antibodies  >5 publications with BMP5 and Eye
 Prostate Antibodies  >5 publications with BMP5 and Prostate
 Liver Antibodies  >4 publications with BMP5 and Liver
 Pancreas Antibodies  >3 publications with BMP5 and Pancreas
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