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anti-BMPR1A antibody :: Rabbit BMPR1A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS855162
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMPR1A, Polyclonal Antibody

★Popular Item★
 Also Known As   

BMPR1A Antibody

 Product Gene Name   

anti-BMPR1A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    174900
 3D Structure    ModBase 3D Structure for P36894
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Predicted: Mouse, Rat
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 Form/Format    Purified by protein affinity column containing 0.02% NaN3
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-BMPR1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BMPR1A antibody

   Rabbit polyclonal BMPR1A (1) antibody was raised against a recombinate human BMPR1A protein 219-453aa (BC028383).
 Product Categories/Family for anti-BMPR1A antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-BMPR1A antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-BMPR1A antibody    ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
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 Testing Data of anti-BMPR1A antibody    anti-BMPR1A antibody Testing Data image
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 Testing Data of anti-BMPR1A antibody    anti-BMPR1A antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for BMPR1A. It may not necessarily be applicable to this product.
 NCBI GI #    41349437
 NCBI GeneID    657
 NCBI Accession #    NP_004320.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004329.2 [Other Products]
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 UniProt Primary Accession #    P36894 [Other Products]
 UniProt Secondary Accession #    Q8NEN8; A8K6U9 [Other Products]
 UniProt Related Accession #    P36894 [Other Products]
 Molecular Weight    60,198 Da
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 NCBI Official Full Name    bone morphogenetic protein receptor type-1A
 NCBI Official Synonym Full Names    bone morphogenetic protein receptor type 1A
 NCBI Official Symbol    BMPR1A [Similar Products]
 NCBI Official Synonym Symbols   
ALK3; SKR5; CD292; ACVRLK3; 10q23del
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein receptor type-1A
 UniProt Protein Name    Bone morphogenetic protein receptor type-1A
 UniProt Synonym Protein Names   
Activin receptor-like kinase 3; ALK-3; Serine/threonine-protein kinase receptor R5; SKR5; CD_antigen: CD292
 Protein Family    Bone morphogenetic protein receptor
 UniProt Gene Name    BMPR1A [Similar Products]
 UniProt Synonym Gene Names    ACVRLK3; ALK3; BMP type-1A receptor; BMPR-1A; ALK-3; SKR5 [Similar Products]
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 NCBI Summary for BMPR1A    The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMPR1A    On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
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Product References and Citations for anti-BMPR1A antibody

   (1) Giambra, V., Cianci, R., Lolli, S., et al. Allele *1 of HS1.2 enhancer associates with selective IgA deficiency and IgM concentration. J. Immunol. 183 (12), 8280-8285 (2009).
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 Research Articles on BMPR1A    1. both bone morphogenetic protein 2 (BMP2) and BMP6 are proangiogenic in vitro and ex vivo and that the BMP type I receptors, activin receptor-like kinase 3 (ALK3) and ALK2, play crucial and distinct roles in this process.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BMPR1A antibodyPathways associated with anti-BMPR1A antibody
 Reference Product  PubMed Publications
 BMPR2 antibody  >262 publications with BMPR1A and BMPR2
 BMP2 antibody  >164 publications with BMPR1A and BMP2
 BMP4 antibody  >134 publications with BMPR1A and BMP4
 SMAD4 antibody  >91 publications with BMPR1A and SMAD4
 BMP7 antibody  >69 publications with BMPR1A and BMP7
 GDF5 antibody  >31 publications with BMPR1A and GDF5
 BMP6 antibody  >30 publications with BMPR1A and BMP6
 SMAD7 antibody  >12 publications with BMPR1A and SMAD7
 ACVR2B antibody  >8 publications with BMPR1A and ACVR2B
 Products by Pathway  Pathway Diagram
 BMP Signalling And Regulation Pathway antibodies  BMP Signalling And Regulation Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Heart Development Pathway antibodies  Heart Development Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By BMP Pathway antibodies  Signaling By BMP Pathway Diagram
Diseases associated with anti-BMPR1A antibodyOrgans/Tissues associated with anti-BMPR1A antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >131 publications with BMPR1A and Neoplasms
 Congenital Abnormalities Antibodies  >53 publications with BMPR1A and Congenital Abnormalities
 Juvenile polyposis syndrome Antibodies  >38 publications with BMPR1A and Juvenile polyposis syndrome
 Adenoma Antibodies  >36 publications with BMPR1A and Adenoma
 Inflammation Antibodies  >17 publications with BMPR1A and Inflammation
 Female Urogenital Diseases Antibodies  >17 publications with BMPR1A and Female Urogenital Diseases
 Breast Neoplasms Antibodies  >14 publications with BMPR1A and Breast Neoplasms
 Embryo Loss Antibodies  >13 publications with BMPR1A and Embryo Loss
 Heart Defects, Congenital Antibodies  >13 publications with BMPR1A and Heart Defects, Congenital
 Hyperplasia Antibodies  >12 publications with BMPR1A and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >106 publications with BMPR1A and Embryonic Tissue
 Muscle Antibodies  >70 publications with BMPR1A and Muscle
 Connective Tissue Antibodies  >50 publications with BMPR1A and Connective Tissue
 Heart Antibodies  >48 publications with BMPR1A and Heart
 Brain Antibodies  >46 publications with BMPR1A and Brain
 Vascular Antibodies  >45 publications with BMPR1A and Vascular
 Ovary Antibodies  >43 publications with BMPR1A and Ovary
 Lung Antibodies  >23 publications with BMPR1A and Lung
 Mouth Antibodies  >23 publications with BMPR1A and Mouth
 Intestine Antibodies  >23 publications with BMPR1A and Intestine
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