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anti-MYBL2 antibody :: Goat BMYB/MYBL2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421249
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMYB/MYBL2, Polyclonal Antibody

 Also Known As   

Goat anti-BMYB/MYBL2 Antibody

 Product Synonym Names    MYBL2; BMYB; v-myb myeloblastosis viral oncogene homolog (avian)-like 2; HGNC: 7548; MGC15600; MYB-related protein B; v-myb avian myeloblastosis viral oncogene homolog-like 2; B-MYB; MYBL2 antibody; BMYB antibody; v-myb myeloblastosis viral oncogene homolog (avian)-like 2 antibody; HGNC: 7548 antibody; MGC15600 antibody; MYB-related protein B antibody; v-myb avian myeloblastosis viral oncogene homolog-like 2 antibody; B-MYB antibody; BMYB / MYBL2
 Product Gene Name   

anti-MYBL2 antibody

[Similar Products]
 Product Synonym Gene Name    BMYB [Similar Products]
 Antibody/Peptide Pairs    BMYB / MYBL2 peptide (MBS425725) is used for blocking the activity of BMYB/MYBL2 antibody (MBS421249)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    QEKARQLLGR LKPSH
 OMIM    601415
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Rat; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-QEKARQLLGRLKPSH, from the C Terminus of the protein sequence according to NP_002457.1.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-MYBL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MYBL2 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-MYBL2 antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 100kDa band observed in rat stomach lysates (calculated MW of 78.8kDa according to Human NP_002457.1). Recommended concentration: 0.1-0.3ug/ml.
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 Western Blot (WB) of anti-MYBL2 antibody    (0.1ug/ml) staining of rat stomach lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-MYBL2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for MYBL2. It may not necessarily be applicable to this product.
 NCBI GI #    4505293
 NCBI GeneID    4605
 NCBI Accession #    NP_002457.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002466.3 [Other Products]
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 UniProt Secondary Accession #    Q53F07; B2RBS5; B7Z8D9; F8W6N6 [Other Products]
 UniProt Related Accession #    P10244 [Other Products]
 Molecular Weight    75,865 Da
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 NCBI Official Full Name    myb-related protein B isoform 1
 NCBI Official Synonym Full Names    MYB proto-oncogene like 2
 NCBI Official Symbol    MYBL2 [Similar Products]
 NCBI Official Synonym Symbols   
BMYB; B-MYB
[Similar Products]
 NCBI Protein Information    myb-related protein B
 UniProt Protein Name    Myb-related protein B
 UniProt Synonym Protein Names   
Myb-like protein 2
 Protein Family    Myb-related protein
 UniProt Gene Name    MYBL2 [Similar Products]
 UniProt Synonym Gene Names    BMYB; B-Myb [Similar Products]
 UniProt Entry Name    MYBB_HUMAN
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 NCBI Summary for MYBL2    The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
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 UniProt Comments for MYBL2    B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

Protein type: Motility/polarity/chemotaxis; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 20q13.1

Cellular Component: nucleoplasm

Molecular Function: protein binding; transcription factor activity

Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; transcription from RNA polymerase II promoter
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 Research Articles on MYBL2    1. We found that B-Myb upregulated expression of the key epithelial-to-mesenchymal transition regulator snail and that it mediated epithelial-to-mesenchymal transition activation and cell invasion by B-Myb.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MYBL2 antibodyPathways associated with anti-MYBL2 antibody
 Reference Product  PubMed Publications
 CDK2 antibody  >18 publications with MYBL2 and CDK2
 CCNB1 antibody  >14 publications with MYBL2 and CCNB1
 E2F4 antibody  >13 publications with MYBL2 and E2F4
 RBL1 antibody  >12 publications with MYBL2 and RBL1
 LIN9 antibody  >8 publications with MYBL2 and LIN9
 CCNB2 antibody  >3 publications with MYBL2 and CCNB2
 CDK1 antibody  >3 publications with MYBL2 and CDK1
 CREBBP antibody  >1 publications with MYBL2 and CREBBP
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 E2F Transcription Factor Network Pathway antibodies  E2F Transcription Factor Network Pathway Diagram
 G0 And Early G1 Pathway antibodies  G0 And Early G1 Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Gastric Cancer Network 1 Pathway antibodies  Gastric Cancer Network 1 Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Mitotic G1-G1/S Phases Pathway antibodies  Mitotic G1-G1/S Phases Pathway Diagram
 Mitotic G2-G2/M Phases Pathway antibodies  Mitotic G2-G2/M Phases Pathway Diagram
Diseases associated with anti-MYBL2 antibodyOrgans/Tissues associated with anti-MYBL2 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >27 publications with MYBL2 and Breast Neoplasms
 Adenocarcinoma Antibodies  >19 publications with MYBL2 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >8 publications with MYBL2 and Carcinoma, Hepatocellular
 Uterine Neoplasms Antibodies  >8 publications with MYBL2 and Uterine Neoplasms
 Neoplasms, Experimental Antibodies  >6 publications with MYBL2 and Neoplasms, Experimental
 Liver Diseases Antibodies  >5 publications with MYBL2 and Liver Diseases
 Liver Neoplasms Antibodies  >5 publications with MYBL2 and Liver Neoplasms
 Prostatic Neoplasms Antibodies  >5 publications with MYBL2 and Prostatic Neoplasms
 Fibrosis Antibodies  >3 publications with MYBL2 and Fibrosis
 Inflammation Antibodies  >3 publications with MYBL2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >18 publications with MYBL2 and Blood
 Liver Antibodies  >12 publications with MYBL2 and Liver
 Muscle Antibodies  >12 publications with MYBL2 and Muscle
 Bone Antibodies  >10 publications with MYBL2 and Bone
 Vascular Antibodies  >9 publications with MYBL2 and Vascular
 Prostate Antibodies  >7 publications with MYBL2 and Prostate
 Lung Antibodies  >7 publications with MYBL2 and Lung
 Bone Marrow Antibodies  >6 publications with MYBL2 and Bone Marrow
 Testis Antibodies  >6 publications with MYBL2 and Testis
 Embryonic Tissue Antibodies  >5 publications with MYBL2 and Embryonic Tissue
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