AAH10648.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
NCBI Official Synonym Full Names
BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
NCBI Protein Information
transcription factor IIIB 50 kDa subunit; BRF-2; hBRFU; hTFIIIB50; B-related factor 2; transcription factor IIB- related factor, TFIIIB50; RNA polymerase III transcription initiation factor BRFU; BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
UniProt Protein Name
Transcription factor IIIB 50 kDa subunit
UniProt Synonym Protein Names
B-related factor 2; BRF-2; hBRFU
UniProt Synonym Gene Names
UniProt Entry Name
BRF2_HUMAN
NCBI Summary for BRF2
This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein. [provided by RefSeq, Jul 2008]
UniProt Comments for BRF2
TFIIIB50: General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Belongs to the TFIIB family.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 8p11.23
Cellular Component: nucleoplasm
Molecular Function: zinc ion binding
Biological Process: transcription from RNA polymerase III promoter; regulation of transcription, DNA-dependent; transcription initiation; gene expression
Research Articles on BRF2
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Products associated with anti-BRF2 antibody
Pathways associated with anti-BRF2 antibody
Diseases associated with anti-BRF2 antibody
Organs/Tissues associated with anti-BRF2 antibody
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