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anti-Angptl8 antibody :: Rabbit anti-Mouse Betatrophin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1490128 anti-Angptl8 antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Betatrophin (Angptl8), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-mouse Betatrophin polyclonal Antibody, HRP conjugated

 Product Synonym Names    Angiopoietin-like protein 8; Lipasin; Refeeding-induced fat and liver protein; Gm6484; Angptl8; Rifl
 Product Gene Name   

anti-Angptl8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q8R1L8
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    HRP
 Immunogen    Recombinant mouse Betatrophin protein
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-Angptl8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Angptl8 antibody

   Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage.
 Applications Tested/Suitable for anti-Angptl8 antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for Angptl8. It may not necessarily be applicable to this product.
 NCBI GI #    124301204
 NCBI GeneID    624219
 NCBI Accession #    NP_001074409.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001080940.1 [Other Products]
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 UniProt Primary Accession #    Q8R1L8 [Other Products]
 UniProt Related Accession #    Q8R1L8 [Other Products]
 Molecular Weight    22,063 Da [Similar Products]
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 NCBI Official Full Name    angiopoietin-like protein 8
 NCBI Official Synonym Full Names    angiopoietin-like 8
 NCBI Official Symbol    Angptl8 [Similar Products]
 NCBI Official Synonym Symbols   
Rifl; Gm6484; EG624219
[Similar Products]
 NCBI Protein Information    angiopoietin-like protein 8
 UniProt Protein Name    Angiopoietin-like protein 8
 UniProt Synonym Protein Names   
Betatrophin
 Protein Family    Angiopoietin-like protein
 UniProt Gene Name    Gm6484 [Similar Products]
 UniProt Entry Name    BETAT_MOUSE
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 UniProt Comments for Angptl8    EG624219: Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. In response to food intake. Interacts with ANGPTL3

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: cell maturation; cellular lipid metabolic process; fat cell differentiation; glucose metabolic process; lipid metabolic process; negative regulation of lipoprotein lipase activity; regulation of lipid metabolic process; regulation of lipoprotein metabolic process
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 Research Articles on Angptl8    1. A monoclonal antibody against Angptl8, a feeding-induced hepatokine, lowers serum triglyceride levels when injected into mice. Angptl8 inhibits the activity of lipoprotein lipase in cardiac and skeletal muscle, but not in white adipose tissue. Therefore, Angptl8 acts, at least in part, in an endocrine manner, and its inhibition has therapeutical potential in treating hypertriglyceridemia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Angptl8 antibodyOrgans/Tissues associated with anti-Angptl8 antibody
 Reference Product  PubMed Publications
 Angptl4 antibody  >5 publications with Angptl8 and Angptl4
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >11 publications with Angptl8 and Liver
 Heart Antibodies  >4 publications with Angptl8 and Heart
 Thyroid Antibodies  >1 publications with Angptl8 and Thyroid
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