Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow Bip rightarrow Polyclonal Bip  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • hnRNP Q Antibody
 • Intercellular Adhesion Molecule 1 (ICAM-1) ELISA Kit
 • Glycerin ELISA Kit
 • Alpha Synuclein (SNCA) ELISA Kit
 • Hydroxylysyl Pyridinoline (HP) ELISA Kit
 • Amylin ELISA Kit
 • Crystal Proteins beta (CRYbeta) ELISA Kit
 • Macrophage Chemotactic Factor (MCF) ELISA Kit
 • Glyceraldehyde 3 Phosphate Dehydrogenase (GAPDH) ELISA Kit
 • Crystal Proteins alpha (CRY alpha) ELISA Kit
 • Testosterone ELISA Kit
 • Epiligrin ELISA Kit
 • Lipoprotein A (LP-A) ELISA Kit
 • Axis Inhibition Protein (AXIN) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-Bip antibody :: Rabbit Bip Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS857422
Testing Data
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bip, Polyclonal Antibody

 Also Known As   

Bip Antibody

 Product Gene Name   

anti-Bip antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    138120
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Form/Format    Each vial at least contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.1% sodium azide.
 Concentration    100ug/100ul (lot specific)
Section Bar
 Immunogen    affinity purification
 Species    Rabbit
Section Bar
 Preparation and Storage    Store at 4 degree C or -20 degree C (with 50% glycerol); Minimize freeze-thaw cycles; Non-hazardous.
 Other Notes    Small volumes of anti-Bip antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-Bip antibody

   Background: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
 Product Categories/Family for anti-Bip antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-Bip antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-Bip antibody    WB: 1:500, IHC: 1:50-200
Section Bar
 Testing Data of anti-Bip antibody    anti-Bip antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for Bip. It may not necessarily be applicable to this product.
 NCBI GI #    16507237
 NCBI GeneID    3309
 NCBI Accession #    NP_005338.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005347.4 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q2EF78; Q9NPF1; Q9UK02; B0QZ61 [Other Products]
 UniProt Related Accession #    P11021 [Other Products]
 Molecular Weight    72,333 Da
Table BarTOPTable Bar
 NCBI Official Full Name    78 kDa glucose-regulated protein
 NCBI Official Synonym Full Names    heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
 NCBI Official Symbol    HSPA5 [Similar Products]
 NCBI Official Synonym Symbols   
BIP; MIF2; GRP78; HEL-S-89n
[Similar Products]
 NCBI Protein Information    78 kDa glucose-regulated protein; immunoglobulin heavy chain-binding protein; epididymis secretory sperm binding protein Li 89n; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78
 UniProt Protein Name    78 kDa glucose-regulated protein
 UniProt Synonym Protein Names   
Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP
 Protein Family    Biphenyl dioxygenase
 UniProt Gene Name    HSPA5 [Similar Products]
 UniProt Synonym Gene Names    GRP78; GRP-78; BiP [Similar Products]
 UniProt Entry Name    GRP78_HUMAN
Section Bar
 NCBI Summary for Bip    The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010]
Section Bar
 UniProt Comments for Bip    GRP78: a member of the HSP family of molecular chaperones required for endoplasmic reticulum integrity and stress-induced autophagy. Plays a central role in regulating the unfolded protein response (UPR), and is an obligatory component of autophagy in mammalian cells. May play an important role in cellular adaptation and oncogenic survival. One of the client proteins of GRP78 is protein double-stranded RNA-activated protein-like endoplasmic reticulum kinase (PERK). Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.

Protein type: Heat shock protein; Chaperone

Chromosomal Location of Human Ortholog: 9q33.3

Cellular Component: signalosome; endoplasmic reticulum membrane; focal adhesion; cell surface; smooth endoplasmic reticulum; mitochondrion; endoplasmic reticulum; endoplasmic reticulum lumen; ER-Golgi intermediate compartment; membrane; melanosome; plasma membrane; integral to endoplasmic reticulum membrane; midbody; nucleus

Molecular Function: protein domain specific binding; protein binding; enzyme binding; ubiquitin protein ligase binding; chaperone binding; unfolded protein binding; ATPase activity; ribosome binding; misfolded protein binding; calcium ion binding; glycoprotein binding; ATP binding

Biological Process: platelet activation; ER-associated protein catabolic process; cerebellum structural organization; unfolded protein response; cerebellar Purkinje cell layer development; cellular response to glucose starvation; cellular protein metabolic process; substantia nigra development; unfolded protein response, activation of signaling protein activity; platelet degranulation; positive regulation of protein ubiquitination; negative regulation of transforming growth factor beta receptor signaling pathway; blood coagulation; ER overload response; positive regulation of cell migration; negative regulation of apoptosis
Table BarTOPTable Bar
 Research Articles on Bip    1. JNK contributes to the tumorigenic potential of human cholangiocarcinoma cells through the mTOR pathway regulated GRP78 induction.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-Bip antibodyPathways associated with anti-Bip antibody
 Reference Product  PubMed Publications
 ATF6 antibody  >29 publications with Bip and ATF6
 ATF4 antibody  >26 publications with Bip and ATF4
 ERN1 antibody  >8 publications with Bip and ERN1
 HYOU1 antibody  >7 publications with Bip and HYOU1
 SIL1 antibody  >5 publications with Bip and SIL1
 EIF2AK3 antibody  >2 publications with Bip and EIF2AK3
 Products by Pathway  Pathway Diagram
 ATF6-alpha Activates Chaperone Genes Pathway antibodies  ATF6-alpha Activates Chaperone Genes Pathway Diagram
 ATF6-alpha Activates Chaperones Pathway antibodies  ATF6-alpha Activates Chaperones Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies  Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 IRE1alpha Activates Chaperones Pathway antibodies  IRE1alpha Activates Chaperones Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
Diseases associated with anti-Bip antibodyOrgans/Tissues associated with anti-Bip antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >60 publications with Bip and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >58 publications with Bip and Disease Models, Animal
 Nervous System Diseases Antibodies  >57 publications with Bip and Nervous System Diseases
 Inflammation Antibodies  >33 publications with Bip and Inflammation
 Heart Diseases Antibodies  >21 publications with Bip and Heart Diseases
 Liver Diseases Antibodies  >21 publications with Bip and Liver Diseases
 Necrosis Antibodies  >19 publications with Bip and Necrosis
 Kidney Diseases Antibodies  >13 publications with Bip and Kidney Diseases
 Fatty Liver Antibodies  >10 publications with Bip and Fatty Liver
 Lung Diseases Antibodies  >10 publications with Bip and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >78 publications with Bip and Brain
 Muscle Antibodies  >49 publications with Bip and Muscle
 Blood Antibodies  >46 publications with Bip and Blood
 Heart Antibodies  >38 publications with Bip and Heart
 Liver Antibodies  >38 publications with Bip and Liver
 Kidney Antibodies  >31 publications with Bip and Kidney
 Vascular Antibodies  >22 publications with Bip and Vascular
 Nerve Antibodies  >20 publications with Bip and Nerve
 Pancreas Antibodies  >16 publications with Bip and Pancreas
 Lung Antibodies  >14 publications with Bip and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions