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anti-BMP7 antibody :: Rabbit anti-Mouse Bone Morphogenetic Protein 7 (BMP7) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2007652 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Western Blot (WB)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $230 +1 FREE 8GB USB
0.2 mg  /  $345 +1 FREE 8GB USB
1 mg  /  $815 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bone Morphogenetic Protein 7 (BMP7), Polyclonal Antibody

★Popular Item★
 Also Known As   

Biotin-Linked Antibody to Bone Morphogenetic Protein 7 (BMP7)

 Product Gene Name   

anti-BMP7 antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Bone Morphogenetic Protein 7 (BMP7) (MBS2006305)
Biotin Conjugated Antibody: Bone Morphogenetic Protein 7 (BMP7) (MBS2007652)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG S-STGGKQRS Q NRSKTPKNQE ALRMASVAEN SSSDQRQACK KHELYVSFRD LGWQDWIIAP EGYAAYYCEG ECAFPLNSYM NATNHAIVQT LVHFINPDTV
 Chromosome Location    Chromosome: 20; NC_000020.10 (55743809..55841707, complement). Location: 20q13
 OMIM    112267
 3D Structure    ModBase 3D Structure for P18075
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a rabbit polyclonal antibody raised against BMP7 conjugated to biotin. It has been selected for its ability to recognize BMP7 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant BMP7 (Ser292~His430) expressed in E.coli.
 Unconjugated Antibody    The unconjugated antibody version of this item is also available as catalog #MBS2006305
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-BMP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-BMP7 antibody    Biotin Antibody
 Applications Tested/Suitable for anti-BMP7 antibody   

Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)

 Application Notes for anti-BMP7 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-BMP7 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-BMP7 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for BMP7. It may not necessarily be applicable to this product.
 NCBI GI #    4502427
 NCBI GeneID    655
 NCBI Accession #    NP_001710.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001719.2 [Other Products]
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 UniProt Primary Accession #    P18075 [Other Products]
 UniProt Secondary Accession #    Q9H512; Q9NTQ7 [Other Products]
 UniProt Related Accession #    P18075 [Other Products]
 Molecular Weight    49,313 Da
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 NCBI Official Full Name    bone morphogenetic protein 7
 NCBI Official Synonym Full Names    bone morphogenetic protein 7
 NCBI Official Symbol    BMP7 [Similar Products]
 NCBI Official Synonym Symbols   
OP-1
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 7; osteogenic protein 1
 UniProt Protein Name    Bone morphogenetic protein 7
 UniProt Synonym Protein Names   
Osteogenic protein 1
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP7 [Similar Products]
 UniProt Synonym Gene Names    OP1; BMP-7; OP-1 [Similar Products]
 UniProt Entry Name    BMP7_HUMAN
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 NCBI Summary for BMP7    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP7    BMP7: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1. Expressed in the kidney and bladder. Lower levels seen in the brain. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20q13

Cellular Component: extracellular matrix; extracellular space; extracellular region

Molecular Function: heparin binding; protein binding; growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: axon guidance; negative regulation of MAP kinase activity; response to peptide hormone stimulus; extracellular matrix organization and biogenesis; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; negative regulation of NF-kappaB import into nucleus; embryonic pattern specification; response to estradiol stimulus; negative regulation of cell cycle; regulation of apoptosis; BMP signaling pathway; response to vitamin D; epithelial cell differentiation; ureteric bud development; dendrite development; mesonephros development; skeletal development; embryonic limb morphogenesis; ossification; positive regulation of heterotypic cell-cell adhesion; positive regulation of bone mineralization; odontogenesis of dentine-containing teeth; positive regulation of osteoblast differentiation; negative regulation of neuron differentiation; mesenchymal cell differentiation; branching morphogenesis of a tube; mesoderm formation; inhibition of NF-kappaB transcription factor; cartilage development; negative regulation of mitosis; negative regulation of phosphorylation; epithelial to mesenchymal transition; negative regulation of Notch signaling pathway; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; embryonic camera-type eye morphogenesis; negative regulation of transcription, DNA-dependent; metanephros development; neurite morphogenesis; growth
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 Research Articles on BMP7    1. We demonstrate a cross-talk between BMPs and CRYAB and a major effect of this regulatory interaction on resistance to apoptosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BMP7 antibodyPathways associated with anti-BMP7 antibody
 Reference Product  PubMed Publications
 BMPR2 antibody  >116 publications with BMP7 and BMPR2
 BMPR1A antibody  >74 publications with BMP7 and BMPR1A
 SMAD5 antibody  >41 publications with BMP7 and SMAD5
 BMPR1B antibody  >23 publications with BMP7 and BMPR1B
 ACVR1 antibody  >21 publications with BMP7 and ACVR1
 ACVR2A antibody  >5 publications with BMP7 and ACVR2A
 SOSTDC1 antibody  >4 publications with BMP7 and SOSTDC1
 FST antibody  >3 publications with BMP7 and FST
 NOG antibody  >3 publications with BMP7 and NOG
 CHRD antibody  >2 publications with BMP7 and CHRD
 Products by Pathway  Pathway Diagram
 ALK2 Signaling Events Pathway antibodies  ALK2 Signaling Events Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Molecules Associated With Elastic Fibres Pathway antibodies  Molecules Associated With Elastic Fibres Pathway Diagram
Diseases associated with anti-BMP7 antibodyOrgans/Tissues associated with anti-BMP7 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >135 publications with BMP7 and Neoplasms
 Disease Models, Animal Antibodies  >95 publications with BMP7 and Disease Models, Animal
 Kidney Diseases Antibodies  >87 publications with BMP7 and Kidney Diseases
 Nervous System Diseases Antibodies  >53 publications with BMP7 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >44 publications with BMP7 and Cardiovascular Diseases
 Inflammation Antibodies  >43 publications with BMP7 and Inflammation
 Bone Resorption Antibodies  >32 publications with BMP7 and Bone Resorption
 Necrosis Antibodies  >31 publications with BMP7 and Necrosis
 Hypertension Antibodies  >30 publications with BMP7 and Hypertension
 Renal Insufficiency Antibodies  >29 publications with BMP7 and Renal Insufficiency
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1263 publications with BMP7 and Bone
 Kidney Antibodies  >193 publications with BMP7 and Kidney
 Embryonic Tissue Antibodies  >168 publications with BMP7 and Embryonic Tissue
 Connective Tissue Antibodies  >145 publications with BMP7 and Connective Tissue
 Muscle Antibodies  >101 publications with BMP7 and Muscle
 Brain Antibodies  >99 publications with BMP7 and Brain
 Mouth Antibodies  >85 publications with BMP7 and Mouth
 Eye Antibodies  >68 publications with BMP7 and Eye
 Prostate Antibodies  >35 publications with BMP7 and Prostate
 Heart Antibodies  >34 publications with BMP7 and Heart
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