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Rabbit Brain Natriuretic Peptide (BNP) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS315608 anti-Brain Natriuretic Peptide (BNP) antibody
Unit / Price
0.1 mL  /  $490 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Brain Natriuretic Peptide (BNP), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti BNP

 Product Synonym Names    Rabbit Antibody to Brain Natriuretic Peptide (BNP)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Host    Rabbit
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 Specificity    Brain Natriuretic Peptide (BNP)
Specific for human and rat Brain Natriuretic Peptide (BNP).
Crossreactivity: Brain Natriuretic Peptide - 100%
Human Atrial Natriuretic Peptide - 0%
ACTH (human, 1-39) - 0%
Calcitonin (human) - 0%
Vasoactivive Intestinal Peptide: 0%.
 Form/Format    Neat, Lyophilized
Reconstitute with 0.1ml PBS containing 10mg/ml BSA or with additional buffer for more dilute antibody.
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 Immunogen    Synthetic human Brain Natriuretic Polypeptide covalently attached to a carrier protein (bovine thyroglobulin)
 Buffer    Not applicable
 Preservative    No
 Lyophilized    Yes
 Important Note    Centrifuge before opening to ensure complete recovery of vial contents.
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 Preparation and Storage    Lyophilized: Store at 2 to 8 degree C (preferably in a dessicator).
Reconstituted: Aliquot and store at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-Brain Natriuretic Peptide (BNP) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-Brain Natriuretic Peptide (BNP) antibody    Polyclonal Antibodies to Cardiac Markers
 Applications Tested/Suitable for anti-Brain Natriuretic Peptide (BNP) antibody   

EIA/ELISA, Immunohistochemistry, Radioimmunoassay

 Application Notes for anti-Brain Natriuretic Peptide (BNP) antibody    The antiserum has been characterized by RIA, ELISA and cell staining techniques. Suitable for immunohistochemical techniques. Has been found to stain 3% buffered paraformaldehyde fixed rat brain sections using indirect immunofluorescent procedure at a dilution of 1:1000.
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NCBI/Uniprot data below describe general gene information for Brain Natriuretic Peptide (BNP). It may not necessarily be applicable to this product.
 NCBI GI #    4433127
 NCBI Accession #    BAA04067.1 [Other Products]
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 NCBI Official Full Name    brain natriuretic peptide
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 NCBI Summary for Brain Natriuretic Peptide (BNP)    This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
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 UniProt Comments for Brain Natriuretic Peptide (BNP)    NPPB: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Belongs to the natriuretic peptide family.

Protein type: Hormone; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p36.2

Cellular Component: extracellular space; protein complex; extracellular region

Molecular Function: diuretic hormone activity; hormone activity; receptor binding

Biological Process: cGMP biosynthetic process; negative regulation of angiogenesis; cell surface receptor linked signal transduction; regulation of vasodilation; regulation of blood pressure; receptor guanylyl cyclase signaling pathway; negative regulation of cell growth; regulation of vascular permeability; body fluid secretion; regulation of blood vessel size
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Brain Natriuretic Peptide (BNP) antibodyPathways associated with anti-Brain Natriuretic Peptide (BNP) antibody
 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with Brain Natriuretic Peptide (BNP) and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with anti-Brain Natriuretic Peptide (BNP) antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Brain Natriuretic Peptide (BNP) and Bone
 Connective Tissue Antibodies  >4 publications with Brain Natriuretic Peptide (BNP) and Connective Tissue
 Heart Antibodies  >3 publications with Brain Natriuretic Peptide (BNP) and Heart
 Muscle Antibodies  >3 publications with Brain Natriuretic Peptide (BNP) and Muscle
 Brain Antibodies  >3 publications with Brain Natriuretic Peptide (BNP) and Brain
 Vascular Antibodies  >2 publications with Brain Natriuretic Peptide (BNP) and Vascular
 Embryonic Tissue Antibodies  >2 publications with Brain Natriuretic Peptide (BNP) and Embryonic Tissue
 Ear Antibodies  >1 publications with Brain Natriuretic Peptide (BNP) and Ear
 Kidney Antibodies  >1 publications with Brain Natriuretic Peptide (BNP) and Kidney
 Umbilical Cord Antibodies  >1 publications with Brain Natriuretic Peptide (BNP) and Umbilical Cord
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