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anti-CRP antibody :: Goat C-REACTIVE PROTEIN Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS224050 anti-CRP antibody
Unit / Price
1 mL  /  $175 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-REACTIVE PROTEIN (CRP), Polyclonal Antibody

 Also Known As   

GOAT ANTI HUMAN C-REACTIVE PROTEIN

 Product Gene Name   

anti-CRP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123260
 3D Structure    ModBase 3D Structure for P02741
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Goat
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 Specificity    This item recognizes human C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation.

Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease (CVD).

This reagent is available in bulk quantities and may be made available in other formats. Please enquire for further details.
 Form/Format    Serum
Serum - liquid
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
 Immunogen    Purified human C-Reactive Protein
Buffer Solution
 Antiserum Preparation    Antisera to Human C-Reactive Protein were raised by repeated immunisation of goats with highly purified antigen
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CRP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CRP antibody

   MBS224050 recognizes human C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver, in response to cytokine stimulation. Levels of plasma CRP are significantly increased during the acute phase response, tissue injury and infection and can be used diagnostically as a marker of inflammation, disease progress and risk assessment of cardiovascular disease (CVD). This reagent is available in bulk quantities and may be made available in other formats. Please enquire for further details.
 Applications Tested/Suitable for anti-CRP antibody   

Turbidimetry (TB)

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NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
 NCBI GI #    55770842
 NCBI GeneID    1401
 NCBI Accession #    NP_000558.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000567.2 [Other Products]
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 UniProt Primary Accession #    P02741 [Other Products]
 UniProt Secondary Accession #    Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0 [Other Products]
 UniProt Related Accession #    P02741 [Other Products]
 Molecular Weight    10,415 Da [Similar Products]
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 NCBI Official Full Name    C-reactive protein
 NCBI Official Synonym Full Names    C-reactive protein, pentraxin-related
 NCBI Official Symbol    CRP [Similar Products]
 NCBI Official Synonym Symbols   
PTX1
[Similar Products]
 NCBI Protein Information    C-reactive protein; pentraxin 1
 UniProt Protein Name    C-reactive protein
 Protein Family    Cryparin
 UniProt Gene Name    CRP [Similar Products]
 UniProt Synonym Gene Names    PTX1 [Similar Products]
 UniProt Entry Name    CRP_HUMAN
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 NCBI Summary for CRP    The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
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 UniProt Comments for CRP    CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; virion binding; low-density lipoprotein binding; cholesterol binding; calcium ion binding

Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; wound healing; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; acute-phase response; response to hypoxia; opsonization; inflammatory response; complement activation, classical pathway; aging
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 Research Articles on CRP    1. half- and full-marathon wheelchair races increased plasma IL-6, but not TNF-alpha and high-sensitivity C-reactive protein
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRP antibodyPathways associated with anti-CRP antibody
 Reference Product  PubMed Publications
 ICAM1 antibody  >497 publications with CRP and ICAM1
 IL6 antibody  >483 publications with CRP and IL6
 SERPINE1 antibody  >321 publications with CRP and SERPINE1
 STAT3 antibody  >36 publications with CRP and STAT3
 CFH antibody  >23 publications with CRP and CFH
 LEP antibody  >9 publications with CRP and LEP
 FCGR2A antibody  >7 publications with CRP and FCGR2A
 FN1 antibody  >2 publications with CRP and FN1
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with anti-CRP antibodyOrgans/Tissues associated with anti-CRP antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11675 publications with CRP and Inflammation
 Cardiovascular Diseases Antibodies  >8544 publications with CRP and Cardiovascular Diseases
 Infection Antibodies  >4623 publications with CRP and Infection
 Heart Diseases Antibodies  >4088 publications with CRP and Heart Diseases
 Metabolic Diseases Antibodies  >3851 publications with CRP and Metabolic Diseases
 Myocardial Ischemia Antibodies  >3275 publications with CRP and Myocardial Ischemia
 Necrosis Antibodies  >3268 publications with CRP and Necrosis
 Atherosclerosis Antibodies  >2906 publications with CRP and Atherosclerosis
 Arthritis, Rheumatoid Antibodies  >2041 publications with CRP and Arthritis, Rheumatoid
 Pain Antibodies  >2030 publications with CRP and Pain
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1439 publications with CRP and Liver
 Pancreas Antibodies  >151 publications with CRP and Pancreas
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