NP_001316999.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,877 Da
NCBI Official Full Name
C-type lectin domain family 10 member A isoform 3
NCBI Official Synonym Full Names
C-type lectin domain family 10 member A
NCBI Official Synonym Symbols
HML; MGL; HML2; CD301; CLECSF13; CLECSF14 [Similar Products]
NCBI Protein Information
C-type lectin domain family 10 member A
UniProt Protein Name
C-type lectin domain family 10 member A
UniProt Synonym Protein Names
C-type lectin superfamily member 14; Macrophage lectin 2; CD_antigen: CD301
UniProt Synonym Gene Names
NCBI Summary for CLEC10A
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for CLEC10A
CLEC10A: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: plasma membrane
Research Articles on CLEC10A
Precautions
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Pathways associated with anti-CLEC10A antibody
Diseases associated with anti-CLEC10A antibody
Organs/Tissues associated with anti-CLEC10A antibody
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