NP_976065.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
C-X-C motif chemokine 3
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 3
NCBI Protein Information
C-X-C motif chemokine 3
UniProt Protein Name
C-X-C motif chemokine 3
UniProt Synonym Protein Names
Dendritic cell inflammatory protein 1
UniProt Entry Name
CXCL3_MOUSE
NCBI Summary for Cxcl3
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. [provided by RefSeq, May 2013]
UniProt Comments for Cxcl3
CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted
Cellular Component: cytosol; extracellular region; extracellular space
Molecular Function: chemokine activity; CXCR chemokine receptor binding; cytokine activity; protein binding
Biological Process: chemotaxis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; neutrophil chemotaxis; regulation of cell proliferation; response to lipopolysaccharide
Research Articles on Cxcl3
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Products associated with anti-Cxcl3 antibody
Pathways associated with anti-Cxcl3 antibody
Diseases associated with anti-Cxcl3 antibody
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