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anti-DRAXIN antibody :: Rabbit C1orf187 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS540543 anti-DRAXIN antibody
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C1orf187 (DRAXIN), Polyclonal Antibody

 Also Known As   

C1orf187 Antibody

 Product Synonym Names    AGPA3119; Chromosome 1 open reading frame 187; Dorsal inhibitory axon guidance protein; Dorsal repulsive axon guidance protein; FLJ34999; MGC117222; Neucrin; UNQ3119 antibody
 Product Gene Name   

anti-DRAXIN antibody

[Similar Products]
 Matching Pairs    Antibody: C1orf187 (MBS540543)
Positive Control: C1orf187 (MBS542711)
 Antibody/Peptide Pairs    C1orf187 peptide (MBS543601) is used for blocking the activity of C1orf187 antibody (MBS540543)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612682
 3D Structure    ModBase 3D Structure for Q8NBI3
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Mouse, Rat, Chicken
Predicted: Bovine, Human, Monkey
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 Form/Format    Affinity Purified
 Concentration    0.64 ug/ul in antibody stabilization buffer (lot specific)
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 Immunogen    Synthetic peptide taken within amino acid region 300-330 on C terminal region of Human Draxin protein.
 Molecular Function    Wnt signaling pathway
 Structure    Interacts with LRP6
 Subcellular Location    Secreted
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-DRAXIN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DRAXIN antibody

   Affinity Purified Draxin Antibody
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures.
 Product Categories/Family for anti-DRAXIN antibody    Primary Antibodies; Neuroscience; Neurogenesis & Plasticity; C1orf187 Antibody
 Applications Tested/Suitable for anti-DRAXIN antibody   

ELISA (EIA), Immunocytochemistry (ICC), Western Blot (WB)

 Application Notes for anti-DRAXIN antibody    Dot Blot: 1:20,000-1:50,000
ELISA: 1:20,000-1:50,000
Immunocytochemistry: 1:100
Western Blot: 1:500-1:1,000
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NCBI/Uniprot data below describe general gene information for DRAXIN. It may not necessarily be applicable to this product.
 NCBI GI #    86990448
 NCBI GeneID    374946
 NCBI Accession #    NP_940947.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_198545.3 [Other Products]
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 UniProt Primary Accession #    Q8NBI3 [Other Products]
 UniProt Secondary Accession #    Q5SNX0; Q6UWK8; B6EV15 [Other Products]
 UniProt Related Accession #    Q8NBI3 [Other Products]
 Molecular Weight    38,650 Da [Similar Products]
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 NCBI Official Full Name    draxin
 NCBI Official Synonym Full Names    dorsal inhibitory axon guidance protein
 NCBI Official Symbol    DRAXIN [Similar Products]
 NCBI Official Synonym Symbols   
UNQ3119; neucrin; AGPA3119; C1orf187
[Similar Products]
 NCBI Protein Information    draxin
 UniProt Protein Name    Draxin
 UniProt Synonym Protein Names   
Dorsal inhibitory axon guidance protein
 Protein Family    Draxin
 UniProt Gene Name    DRAXIN [Similar Products]
 UniProt Entry Name    DRAXI_HUMAN
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 UniProt Comments for DRAXIN    DRAXIN: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. Belongs to the draxin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: extracellular region

Molecular Function: protein binding

Biological Process: axon guidance; commissural neuron differentiation in the spinal cord; dorsal spinal cord development; forebrain development; negative regulation of axon extension; negative regulation of neuron apoptosis; Wnt receptor signaling pathway
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 Research Articles on DRAXIN    1. results suggest that draxin functions as a repulsive guidance cue for PCN migration. However, we observed no significant differences in PCN distribution between draxin(-/-) and wild type embryos.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-DRAXIN antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >10 publications with DRAXIN and Brain
 Embryonic Tissue Antibodies  >4 publications with DRAXIN and Embryonic Tissue
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