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anti-C4.4A antibody :: Rabbit C4.4A / LYPD3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS241518
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C4.4A / LYPD3, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human C4.4A / LYPD3

 Product Synonym Names    Anti-C4.4A / LYPD3 Antibody (C-Terminus) IHC-plus; LYPD3; C4.4A; MIG-C4; LY6/PLAUR domain containing 3; Human C4.4A; LYPD3
 Product Gene Name   

anti-C4.4A antibody

[Similar Products]
 Product Synonym Gene Name    LYPD3 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609484
 3D Structure    ModBase 3D Structure for O95274
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Gibbon, Gorilla, Human
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 Specificity    Human LYPD3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.1% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic 13 amino acid peptide from C-terminus of human LYPD3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Panda (92%); Mouse, Rat, Horse (85%).
 Immunogen Type    Synthetic peptide
 Immunogen    C4.4A / LYPD3 antibody was raised against synthetic 13 amino acid peptide from C-terminus of human LYPD3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Panda (92%); Mouse, Rat, Horse (85%).
 Antigen Modification    C-Terminus
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 Preparation and Storage    Long term: -70 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-C4.4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-C4.4A antibody

   C4.4A is a structural homolog of the urokinase-type plasminogen activator receptor (uPAR). It was originally identified as a metastasis-associated membrane protein in malignant urothelium. In literature IHC studies, staining has been observed in suprabasal keratinocytes of chronic wounds and the amniotic membrane of placenta. ISH analysis demonstrated expression in urothelium of the ureter.
 Applications Tested/Suitable for anti-C4.4A antibody   

Immunohistochemistry (IHC - Paraffin)

 Application Notes for anti-C4.4A antibody    IHC-P (15 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-C4.4A antibody    Anti-LYPD3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-C4.4A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-C4.4A antibody    Anti-LYPD3 antibody IHC of human skin, hair follicle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-C4.4A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for C4.4A. It may not necessarily be applicable to this product.
 NCBI GI #    93004088
 NCBI GeneID    27076
 NCBI Accession #    NP_055215.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_014400.2 [Other Products]
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 UniProt Primary Accession #    O95274 [Other Products]
 UniProt Secondary Accession #    Q9UJ74 [Other Products]
 UniProt Related Accession #    O95274 [Other Products]
 Molecular Weight    35,971 Da
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 NCBI Official Full Name    ly6/PLAUR domain-containing protein 3
 NCBI Official Synonym Full Names    LY6/PLAUR domain containing 3
 NCBI Official Symbol    LYPD3 [Similar Products]
 NCBI Official Synonym Symbols   
C4.4A
[Similar Products]
 NCBI Protein Information    ly6/PLAUR domain-containing protein 3; MIG-C4; 2310061G07Rik; matrigel-induced gene C4 protein; GPI-anchored metastasis-associated protein homolog; GPI-anchored metastasis-associated protein C4.4A homolog
 UniProt Protein Name    Ly6/PLAUR domain-containing protein 3
 UniProt Synonym Protein Names   
GPI-anchored metastasis-associated protein C4.4A homolog; Matrigel-induced gene C4 protein; MIG-C4
 UniProt Gene Name    LYPD3 [Similar Products]
 UniProt Synonym Gene Names    C4.4A; MIG-C4 [Similar Products]
 UniProt Entry Name    LYPD3_HUMAN
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 UniProt Comments for C4.4A    LYPD3: Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.

Protein type: Membrane protein, GPI anchor; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: extracellular space; anchored to plasma membrane; integral to membrane

Molecular Function: laminin binding

Biological Process: cell-matrix adhesion
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 Research Articles on C4.4A    1. Tenascin-C expression was significantly associated with C4.4A expression in clinical esophageal squamous carcinoma samples suggesting that there may be a functional role for the C4.4A to induceTenascin-C in vivo.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-C4.4A antibodyDiseases associated with anti-C4.4A antibody
 Reference Product  PubMed Publications
 EGFR antibody  >1 publications with C4.4A and EGFR
 DAG1 antibody  >1 publications with C4.4A and DAG1
 AGR3 antibody  >1 publications with C4.4A and AGR3
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >7 publications with C4.4A and Adenocarcinoma
 Liver Neoplasms Antibodies  >3 publications with C4.4A and Liver Neoplasms
 Hyperplasia Antibodies  >3 publications with C4.4A and Hyperplasia
 Neoplasms, Experimental Antibodies  >2 publications with C4.4A and Neoplasms, Experimental
 Necrosis Antibodies  >1 publications with C4.4A and Necrosis
 Precancerous Conditions Antibodies  >1 publications with C4.4A and Precancerous Conditions
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with C4.4A and Prenatal Exposure Delayed Effects
Organs/Tissues associated with anti-C4.4A antibody
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >8 publications with C4.4A and Lung
 Liver Antibodies  >4 publications with C4.4A and Liver
 Embryonic Tissue Antibodies  >3 publications with C4.4A and Embryonic Tissue
 Esophagus Antibodies  >3 publications with C4.4A and Esophagus
 Skin Antibodies  >3 publications with C4.4A and Skin
 Stomach Antibodies  >2 publications with C4.4A and Stomach
 Uterus Antibodies  >1 publications with C4.4A and Uterus
 Mouth Antibodies  >1 publications with C4.4A and Mouth
 Mammary Gland Antibodies  >1 publications with C4.4A and Mammary Gland
 Placenta Antibodies  >1 publications with C4.4A and Placenta
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