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anti-C4BPa antibody :: Rabbit anti-Mouse C4 Binding Protein Alpha (C4BPa) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2013516 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $330 +1 FREE 8GB USB
1 mg  /  $785 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C4 Binding Protein Alpha (C4BPa), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa)

 Product Gene Name   

anti-C4BPa antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    The target protein is fused with N-terminal His-Tag and its sequence is listed below.
 3D Structure    ModBase 3D Structure for P08607
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is aRabbit polyclonalantibody raised againstC4BPa. It has been selected for its ability to recognizeC4BPa in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    0.35 mg/mL (lot specific)
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 Immunogen    Recombinant C4BPa (Leu358~His469) expressed in E.coli.
 Traits    Liquid
 Organism species    Mus musculus (Mouse)
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2057180
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use
Aliquot and store at -20C for 12 months.

Stability Test: The thermal stability is described by the loss rate.The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropiate storage condition.
 Other Notes    Small volumes of anti-C4BPa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-C4BPa antibody   


 Application Notes for anti-C4BPa antibody    Western blotting: 0.5-2 ug/mL; 1: 170-700
Immunohistochemistry : 5-20 ug/mL; 1: 17-70
Immunocytochemistry : 5-20 ug/mL ; 1:17-70

Optimal working dilutions must be determined by end user.
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 Western Blot (WB) of anti-C4BPa antibody    (Figure. Western Blot; Sample: Recombinant C4BPa, Mouse.)
anti-C4BPa antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-C4BPa antibody    (Figure.DAB staining on IHC-P. Samples: Mouse Tissue)
anti-C4BPa antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for C4BPa. It may not necessarily be applicable to this product.
 NCBI GI #    115430101
 NCBI GeneID    12269
 NCBI Accession #    NP_031602.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_007576.3 [Other Products]
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 UniProt Primary Accession #    P08607 [Other Products]
 UniProt Secondary Accession #    Q91X48 [Other Products]
 UniProt Related Accession #    P08607 [Other Products]
 Molecular Weight    51,524 Da
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 NCBI Official Full Name    C4b-binding protein
 NCBI Official Synonym Full Names    complement component 4 binding protein
 NCBI Official Symbol    C4bp [Similar Products]
 NCBI Official Synonym Symbols   
C4bpa; AI195242
[Similar Products]
 NCBI Protein Information    C4b-binding protein
 UniProt Protein Name    C4b-binding protein
 Protein Family    C4b-binding protein
 UniProt Gene Name    C4bpa [Similar Products]
 UniProt Synonym Gene Names    C4bp; C4bp [Similar Products]
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 UniProt Comments for C4BPa    C4bp:

Chromosomal Location of Human Ortholog: 1 E4|1 56.89 cM

Cellular Component: extracellular region

Molecular Function: protein binding

Biological Process: complement activation, classical pathway; immune system process; innate immune response
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 Research Articles on C4BPa    1. Data suggest that C4bp prevents interaction between Tlr4/MD-2 and its ligand; C4bp does not appear to interact with Tlr3; C4bp binds to macrophage surface Tlr4 and inhibits Tlr/Tlr ligand interaction, thereby inhibiting Tlr4 activation. (C4bp = complement component 4 binding protein; Tlr = toll-like receptor; MD-2 = myeloid differentiation protein-2)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-C4BPa antibodyDiseases associated with anti-C4BPa antibody
 Products by Pathway  Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Pertussis Pathway antibodies  Pertussis Pathway Diagram
 Pertussis Pathway antibodies  Pertussis Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >33 publications with C4BPa and Inflammation
 Cardiovascular Diseases Antibodies  >33 publications with C4BPa and Cardiovascular Diseases
 Immune System Diseases Antibodies  >33 publications with C4BPa and Immune System Diseases
 Blood Coagulation Disorders Antibodies  >18 publications with C4BPa and Blood Coagulation Disorders
 Kidney Diseases Antibodies  >16 publications with C4BPa and Kidney Diseases
 Neoplasms Antibodies  >15 publications with C4BPa and Neoplasms
 Liver Diseases Antibodies  >11 publications with C4BPa and Liver Diseases
 Necrosis Antibodies  >9 publications with C4BPa and Necrosis
 Brain Diseases Antibodies  >7 publications with C4BPa and Brain Diseases
 Death Antibodies  >7 publications with C4BPa and Death
Organs/Tissues associated with anti-C4BPa antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >34 publications with C4BPa and Liver
 Kidney Antibodies  >17 publications with C4BPa and Kidney
 Epididymis Antibodies  >2 publications with C4BPa and Epididymis
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