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anti-MGARP antibody :: Rabbit anti-Human C4orf49 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6008598 anti-MGARP antibody
Unit / Price
0.2 mL  /  $550 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C4orf49 (MGARP), Polyclonal Antibody

 Also Known As   

C4orf49, CT (MGARP, C4orf49, CESP1, HUMMR, OSAP, Protein MGARP, Corneal endothelium-specific protein 1, Hypoxia up-regulated mitochondrial movement regulator protein, Mitochondria-localized glutamic acid-rich protein, Ovary-specific acidic protein)

 Product Synonym Names    Anti -C4orf49, CT (MGARP, C4orf49, CESP1, HUMMR, OSAP, Protein MGARP, Corneal endothelium-specific protein 1, Hypoxia up-regulated mitochondrial movement regulator protein, Mitochondria-localized glutamic acid-rich protein, Ovary-specific acidic protein)
 Product Gene Name   

anti-MGARP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 4; NC_000004.11 (140187317..140201492, complement). Location: 4q31.1
 3D Structure    ModBase 3D Structure for Q8TDB4
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Human
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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 Immunogen    C4orf49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the C-terminal region of human C4orf49.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-MGARP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-MGARP antibody

   The function of this protein remains unknown.
 Product Categories/Family for anti-MGARP antibody    Antibodies; Abs to Mitochondrial Proteins
 Applications Tested/Suitable for anti-MGARP antibody   

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-MGARP antibody    Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
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NCBI/Uniprot data below describe general gene information for MGARP. It may not necessarily be applicable to this product.
 NCBI GI #    74355769
 NCBI GeneID    84709
 NCBI Accession #    AAI04174.1 [Other Products]
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 UniProt Primary Accession #    Q8TDB4 [Other Products]
 UniProt Secondary Accession #    Q9BZC3 [Other Products]
 UniProt Related Accession #    Q8TDB4 [Other Products]
 Molecular Weight    25,390 Da [Similar Products]
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 NCBI Official Full Name    Chromosome 4 open reading frame 49
 NCBI Official Synonym Full Names    mitochondria-localized glutamic acid-rich protein
 NCBI Official Symbol    MGARP [Similar Products]
 NCBI Official Synonym Symbols   
OSAP; HUMMR; CESP-1; C4orf49
[Similar Products]
 NCBI Protein Information    protein MGARP; ovary-specific acidic protein; corneal endothelium-specific protein 1; hypoxia up-regulated mitochondrial movement regulator protein
 UniProt Protein Name    Protein MGARP
 UniProt Synonym Protein Names   
Corneal endothelium-specific protein 1; CESP-1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein
 Protein Family    Protein
 UniProt Gene Name    MGARP [Similar Products]
 UniProt Synonym Gene Names    C4orf49; CESP1; HUMMR; OSAP; CESP-1 [Similar Products]
 UniProt Entry Name    HUMMR_HUMAN
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 UniProt Comments for MGARP    OSAP: Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31.1

Cellular Component: mitochondrion; integral to mitochondrial outer membrane

Molecular Function: protein binding

Biological Process: axon transport of mitochondrion; anterograde axon cargo transport; retrograde axon cargo transport; protein targeting to mitochondrion
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 Research Articles on MGARP    1. The present study identified a proximal core sequence in the MGARP promoter that is composed of two enriched Sp1 binding motifs and established Sp1 as one major MGARP transactivator.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-MGARP antibody
 Organ/Tissue Name  Pubmed Publications
 Adrenal Gland Antibodies  >1 publications with MGARP and Adrenal Gland
 Brain Antibodies  >1 publications with MGARP and Brain
 Eye Antibodies  >1 publications with MGARP and Eye
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