Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow C8B rightarrow Polyclonal C8B  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Kisspeptin 1 (KISS1) ELISA Kit
 • COMP ELISA Kit
 • 10 kDa heat shock protein, mitochondrial (Hspe1) Recombinant Protein
 • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase,... ELISA Kit
 • DIAPH3 Antibody
 • ADAM metallopeptidase domain 8 (ADAM8) ELISA Kit
 • chimerin (chimaerin) 2 (CHN2) Antibody
 • serpin peptidase inhibitor, clade B (ovalbumin) , member 4 (... ELISA Kit
 • H5 (H5N1) (A-Japanese white-eye-Hong Kong-1038-2006) Recombinant Protein
 • Phospho-IRS2 (Y978) Antibody
 • Flt3 Ligand (FLT3LG) ELISA Kit
 • Endotoxin - Gram Negative Antibody
 • BMP7 Recombinant Protein
 • DDX39 (DDX39A) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-C8B antibody :: Rabbit anti-Human, Mouse C8B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044419
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C8B, Polyclonal Antibody

★Popular Item★
 Also Known As   

C8B Antibody

 Product Synonym Names    Complement component C8 beta chain; Complement component 8 subunit beta; C8B
 Product Gene Name   

anti-C8B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    120960
 3D Structure    ModBase 3D Structure for P07358
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
Section Bar
 Species    Human
 Immunogen    Recombinant human Complement component C8 beta chain protein (55-350AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130999
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-C8B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-C8B antibody

   Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
 Applications Tested/Suitable for anti-C8B antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Section Bar
 Western Blot (WB) of anti-C8B antibody    Western blot
All lanes: C8B antibody at 1.28 ug/ml
Lane 1: Hela whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: HepG-2 whole cell lysate
Lane 4: Raji whole cell lysate
Lane 5: Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 67 kDa
Observed band size: 67,50 kDa

anti-C8B antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-C8B antibody    Immunohistochemistry of paraffin-embedded human liver cancer using MBS7044419 at dilution of 1:100
anti-C8B antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-C8B antibody    Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7044419 at dilution of 1:100
anti-C8B antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for C8B. It may not necessarily be applicable to this product.
 NCBI GI #    514239916
 NCBI GeneID    732
 NCBI Accession #    NP_000057.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000066.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P07358 [Other Products]
 UniProt Secondary Accession #    A1L4K7 [Other Products]
 UniProt Related Accession #    P07358 [Other Products]
 Molecular Weight    67,047 Da
Table BarTOPTable Bar
 NCBI Official Full Name    complement component C8 beta chain isoform 1 preproprotein
 NCBI Official Synonym Full Names    complement C8 beta chain
 NCBI Official Symbol    C8B [Similar Products]
 NCBI Official Synonym Symbols   
C82
[Similar Products]
 NCBI Protein Information    complement component C8 beta chain
 UniProt Protein Name    Complement component C8 beta chain
 UniProt Synonym Protein Names   
Complement component 8 subunit beta
 Protein Family    Complement component
 UniProt Gene Name    C8B [Similar Products]
 UniProt Entry Name    CO8B_HUMAN
Section Bar
 NCBI Summary for C8B    This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Section Bar
 UniProt Comments for C8B    C8B: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Defects in C8B are a cause of complement component 8 deficiency type 2 (C8D2). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p32.2

Cellular Component: extracellular region; membrane

Biological Process: complement activation; immune response; regulation of complement activation

Disease: Complement Component 8 Deficiency, Type Ii
Table BarTOPTable Bar
 Research Articles on C8B    1. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-C8B antibodyDiseases associated with anti-C8B antibody
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Complement Activation, Classical Pathway antibodies  Complement Activation, Classical Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with C8B and Inflammation
 Neisseriaceae Infections Antibodies  >4 publications with C8B and Neisseriaceae Infections
 Meningitis Antibodies  >4 publications with C8B and Meningitis
 Necrosis Antibodies  >2 publications with C8B and Necrosis
 Cell Transformation, Neoplastic Antibodies  >1 publications with C8B and Cell Transformation, Neoplastic
Organs/Tissues associated with anti-C8B antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with C8B and Liver
 Lung Antibodies  >2 publications with C8B and Lung
 Brain Antibodies  >1 publications with C8B and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions