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anti-C9 antibody :: anti-Human, Mouse C9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9125401
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C9, Polyclonal Antibody

★Popular Item★
 Also Known As   

C9

 Product Synonym Names    ARMD15, C9D
 Product Gene Name   

anti-C9 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    phenotype 615591
 3D Structure    ModBase 3D Structure for P02748
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 Clonality    Polyclonal
 Isotype    IgG
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity purification
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 Source    Rabbit
 Immunogen    Recombinant funsion protein containing a sequence corresponding to amino acids 22-265 of human C9 (NP_001728.1)
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
 Calculated MW    63 kDa
 Observed MW    70 kDa
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 Preparation and Storage    Store at -20C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-C9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-C9 antibody

   This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
 Product Categories/Family for anti-C9 antibody    Polyclonal
 Applications Tested/Suitable for anti-C9 antibody   

Western Blot (WB)

 Application Notes for anti-C9 antibody    1:500- 1:2000
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 Western Blot (WB) of anti-C9 antibody    Western blot analysis of extracts of mouse liver, using C9 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-C9 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for C9. It may not necessarily be applicable to this product.
 NCBI GI #    1352108
 NCBI GeneID    735
 NCBI Accession #    P02748.2 [Other Products]
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 UniProt Primary Accession #    P02748 [Other Products]
 UniProt Related Accession #    P02748 [Other Products]
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 NCBI Official Full Name    Complement component C9
 NCBI Official Synonym Full Names    complement component 9
 NCBI Official Symbol    C9 [Similar Products]
 NCBI Official Synonym Symbols   
C9D; ARMD15
[Similar Products]
 NCBI Protein Information    complement component C9
 UniProt Protein Name    Complement component C9
 Protein Family    Complement component
 UniProt Gene Name    C9 [Similar Products]
 UniProt Entry Name    CO9_HUMAN
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 NCBI Summary for C9    This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
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 UniProt Comments for C9    C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Extracellular matrix; Membrane protein, multi-pass; Membrane protein, integral; Apoptosis

Chromosomal Location of Human Ortholog: 5p14-p12

Cellular Component: membrane attack complex; integral to plasma membrane; cytoplasm; plasma membrane; extracellular region

Biological Process: complement activation, alternative pathway; regulation of complement activation; innate immune response; hemolysis by symbiont of host red blood cells; complement activation, classical pathway

Disease: Macular Degeneration, Age-related, 15; Complement Component 9 Deficiency
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 Research Articles on C9    1. Data indicate that complement C9 binds to the ATPase domain of mortalin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-C9 antibodyPathways associated with anti-C9 antibody
 Reference Product  PubMed Publications
 CD59 antibody  >152 publications with C9 and CD59
 C8G antibody  >11 publications with C9 and C8G
 C8A antibody  >7 publications with C9 and C8A
 C8B antibody  >6 publications with C9 and C8B
 SERPINC1 antibody  >4 publications with C9 and SERPINC1
 FGG antibody  >2 publications with C9 and FGG
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Complement Activation, Classical Pathway antibodies  Complement Activation, Classical Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
Diseases associated with anti-C9 antibodyOrgans/Tissues associated with anti-C9 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >140 publications with C9 and Inflammation
 Kidney Diseases Antibodies  >130 publications with C9 and Kidney Diseases
 Necrosis Antibodies  >86 publications with C9 and Necrosis
 Brain Diseases Antibodies  >77 publications with C9 and Brain Diseases
 Fatty Liver Antibodies  >63 publications with C9 and Fatty Liver
 Liver Diseases Antibodies  >50 publications with C9 and Liver Diseases
 Heart Diseases Antibodies  >46 publications with C9 and Heart Diseases
 Weight Loss Antibodies  >34 publications with C9 and Weight Loss
 Immunologic Deficiency Syndromes Antibodies  >30 publications with C9 and Immunologic Deficiency Syndromes
 Liver Neoplasms Antibodies  >23 publications with C9 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >253 publications with C9 and Liver
 Muscle Antibodies  >177 publications with C9 and Muscle
 Kidney Antibodies  >174 publications with C9 and Kidney
 Placenta Antibodies  >12 publications with C9 and Placenta
 Pancreas Antibodies  >12 publications with C9 and Pancreas
 Uncharacterized Tissue Antibodies  >1 publications with C9 and Uncharacterized Tissue
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