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anti-CACNB1 antibody :: Rabbit anti-Human CACNB1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7043848
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CACNB1, Polyclonal Antibody

★Popular Item★
 Also Known As   

CACNB1 Antibody

 Product Synonym Names    Voltage-dependent L-type calcium channel subunit beta-1; CAB1; Calcium channel voltage-dependent subunit beta 1; CACNB1; CACNLB1
 Product Gene Name   

anti-CACNB1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    114207
 3D Structure    ModBase 3D Structure for Q02641
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Voltage-dependent L-type calcium channel subunit beta-1 protein (C-170AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32080 / sc-32081 / sc-32079 / sc-32077 / sc-25689
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CACNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CACNB1 antibody

   The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
 Applications Tested/Suitable for anti-CACNB1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-CACNB1 antibody    Western blot
All lanes: CACNB1 antibody at 6.68 ug/ml
+ HepG-2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 66,58,54 kDa
Observed band size: 66 kDa

anti-CACNB1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CACNB1 antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7043848 at dilution 1:100
anti-CACNB1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CACNB1 antibody    Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7043848 at dilution 1:100
anti-CACNB1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CACNB1. It may not necessarily be applicable to this product.
 NCBI GI #    40804468
 NCBI GeneID    782
 NCBI Accession #    NP_000714.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000723.4 [Other Products]
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 UniProt Primary Accession #    Q02641 [Other Products]
 UniProt Secondary Accession #    O15331; Q02639; Q02640; Q8N3X9; Q9C085; Q9UD79; A8K114 [Other Products]
 UniProt Related Accession #    Q02641 [Other Products]
 Molecular Weight    53,006 Da
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 NCBI Official Full Name    voltage-dependent L-type calcium channel subunit beta-1 isoform 1
 NCBI Official Synonym Full Names    calcium voltage-gated channel auxiliary subunit beta 1
 NCBI Official Symbol    CACNB1 [Similar Products]
 NCBI Official Synonym Symbols   
CAB1; CCHLB1; CACNLB1
[Similar Products]
 NCBI Protein Information    voltage-dependent L-type calcium channel subunit beta-1
 UniProt Protein Name    Voltage-dependent L-type calcium channel subunit beta-1
 UniProt Synonym Protein Names   
Calcium channel voltage-dependent subunit beta 1
 Protein Family    Voltage-dependent L-type calcium channel
 UniProt Gene Name    CACNB1 [Similar Products]
 UniProt Synonym Gene Names    CACNLB1; CAB1 [Similar Products]
 UniProt Entry Name    CACB1_HUMAN
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 NCBI Summary for CACNB1    The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CACNB1    CACNB1: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Belongs to the calcium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, calcium

Chromosomal Location of Human Ortholog: 17q21-q22

Cellular Component: plasma membrane

Molecular Function: high voltage-gated calcium channel activity; voltage-gated calcium channel activity

Biological Process: neuromuscular junction development; synaptic transmission; transport
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 Research Articles on CACNB1    1. CACNB1, encoding cardiac L-type calcium channel beta 1 subunit, is a potential target for microRNA-328 in transgenic mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CACNB1 antibodyPathways associated with anti-CACNB1 antibody
 Reference Product  PubMed Publications
 CACNA1C antibody  >3 publications with CACNB1 and CACNA1C
 CACNA1S antibody  >3 publications with CACNB1 and CACNA1S
 CACNA2D1 antibody  >3 publications with CACNB1 and CACNA2D1
 CACNA1H antibody  >2 publications with CACNB1 and CACNA1H
 CACNA1G antibody  >2 publications with CACNB1 and CACNA1G
 CACNA1A antibody  >1 publications with CACNB1 and CACNA1A
 CACNG1 antibody  >1 publications with CACNB1 and CACNG1
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cardiac Conduction Pathway antibodies  Cardiac Conduction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
Diseases associated with anti-CACNB1 antibodyOrgans/Tissues associated with anti-CACNB1 antibody
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >4 publications with CACNB1 and Disease Models, Animal
 Diabetes Mellitus, Type 2 Antibodies  >2 publications with CACNB1 and Diabetes Mellitus, Type 2
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with CACNB1 and Brain
 Heart Antibodies  >3 publications with CACNB1 and Heart
 Nerve Antibodies  >2 publications with CACNB1 and Nerve
 Embryonic Tissue Antibodies  >1 publications with CACNB1 and Embryonic Tissue
 Bone Antibodies  >1 publications with CACNB1 and Bone
 Intestine Antibodies  >1 publications with CACNB1 and Intestine
 Prostate Antibodies  >1 publications with CACNB1 and Prostate
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